review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Athar H Chishti | Q89175184 |
P2093 | author name string | Shafi M Kuchay | |
P2860 | cites work | PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation | Q24301041 |
PTP-1B is an essential positive regulator of platelet integrin signaling | Q24317102 | ||
The calpain system | Q28185062 | ||
Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets | Q28235484 | ||
Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion | Q28280504 | ||
Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation | Q28286323 | ||
Calpain Cleavage of the Cytoplasmic Domain of the Integrin β2 Subunit | Q28291851 | ||
Regulation of cell migration by the calcium-dependent protease calpain | Q29391186 | ||
SNAP-23 is a target for calpain cleavage in activated platelets. | Q30711945 | ||
Disruption of the mouse mu-calpain gene reveals an essential role in platelet function | Q33967742 | ||
Thrombopoietin and thrombin induce tyrosine phosphorylation of Vav in human blood platelets. | Q34064456 | ||
Calpain-catalyzed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets. | Q34070941 | ||
Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain | Q34118592 | ||
The properties of the protein tyrosine phosphatase PTPMEG. | Q34406752 | ||
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction | Q35545284 | ||
Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane | Q36223464 | ||
Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa | Q36233149 | ||
Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active | Q36342597 | ||
Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets | Q36532167 | ||
Inhibition of calpain blocks platelet secretion, aggregation, and spreading | Q37307187 | ||
Calpain cleaves RhoA generating a dominant-negative form that inhibits integrin-induced actin filament assembly and cell spreading | Q38290020 | ||
UVA inactivates protein tyrosine phosphatases by calpain-mediated degradation | Q40103872 | ||
Calpain mediates integrin-induced signaling at a point upstream of Rho family members | Q40941467 | ||
Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function | Q41700251 | ||
Microvesicle release is associated with extensive protein tyrosine dephosphorylation in platelets stimulated by A23187 or a mixture of thrombin and collagen | Q41975625 | ||
The relative role of PLCbeta and PI3Kgamma in platelet activation | Q42116882 | ||
Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases | Q42816004 | ||
Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain | Q42983314 | ||
Regulation of protein-tyrosine phosphatases alpha and epsilon by calpain-mediated proteolytic cleavage | Q43655712 | ||
Activation of a calmodulin-dependent phosphatase by a Ca2+-dependent protease | Q43775807 | ||
Spectrin is associated with membrane-bound actin filaments in platelets and is hydrolyzed by the Ca2+-dependent protease during platelet activation | Q44227887 | ||
Vinculin is proteolyzed by calpain during platelet aggregation: 95 kDa cleavage fragment associates with the platelet cytoskeleton. | Q44965408 | ||
Cleavage of platelet endothelial cell adhesion molecule-1 (PECAM-1) in platelets exposed to high shear stress. | Q45154427 | ||
The role of calpain in stimulus-response coupling: evidence that calpain mediates agonist-induced expression of procoagulant activity in platelets | Q46045536 | ||
Dystrophin-related protein in the platelet membrane skeleton. Integrin-induced change in detergent-insolubility and cleavage by calpain in aggregating platelets | Q46311565 | ||
Proteolysis leads to the appearance of the long form of beta3-endonexin in human platelets | Q46427353 | ||
A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation. | Q46728083 | ||
Purification and characterization of a Ca(2+)-activated thiol protease from Drosophila melanogaster | Q48432508 | ||
Plasma membrane Ca2+-ATPase isoform 4b is phosphorylated on tyrosine 1176 in activated human platelets. | Q50318700 | ||
Contribution of PAR-1, PAR-4 and GPIbalpha in intracellular signaling leading to the cleavage of the beta3 cytoplasmic domain during thrombin-induced platelet aggregation. | Q50955441 | ||
Identification and characterization of two novel calpain large subunit genes. | Q52128241 | ||
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain. | Q53602922 | ||
Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix | Q62665022 | ||
Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets | Q69952539 | ||
The Ca2+ -activated protease (calpain) modulates Ca2+/calmodulin dependent activity of smooth muscle myosin light chain kinase | Q70185820 | ||
Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide | Q71466799 | ||
Antibodies specific for proteolyzed forms of protein kinase C alpha | Q71578021 | ||
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors | Q71623372 | ||
Association of the protein tyrosine phosphatase PTP1C with the protein tyrosine kinase c-Src in human platelets | Q71793268 | ||
Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin alphaIIbbeta3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots | Q71984999 | ||
pp60src is an endogenous substrate for calpain in human blood platelets | Q72083293 | ||
Calpain-induced down-regulation of protein kinase C inhibits dense-granule secretion in human platelets. Inhibition of platelet aggregation or calpain activity preserves protein kinase C and restores full secretion | Q72364986 | ||
Endogenous cleavage of phospholipase C-beta 3 by agonist-induced activation of calpain in human platelets | Q72591866 | ||
Proteolysis of platelet cortactin by calpain | Q73541817 | ||
Calpain regulation of cytoskeletal signaling complexes in von Willebrand factor-stimulated platelets. Distinct roles for glycoprotein Ib-V-IX and glycoprotein IIb-IIIa (integrin alphaIIbbeta3) in von Willebrand factor-induced signal transduction | Q73617879 | ||
Cytoskeletal proteins and platelet signaling | Q74314920 | ||
Tyrosine unphosphorylated platelet SHP-1 is a substrate for calpain | Q77545456 | ||
SNARE protein degradation upon platelet activation: calpain cleaves SNAP-23 | Q78696375 | ||
A role for the intracellular protease calpain in the activation of store-operated calcium entry in human platelets | Q80049431 | ||
Phosphatidylinositol 4,5-bisphosphate regulates activation-induced platelet microparticle formation | Q81659598 | ||
P433 | issue | 3 | |
P304 | page(s) | 249-254 | |
P577 | publication date | 2007-05-01 | |
P1433 | published in | Current Opinion in Hematology | Q15757961 |
P1476 | title | Calpain-mediated regulation of platelet signaling pathways | |
P478 | volume | 14 |
Q37981642 | Abundance- and Activity-Based Proteomics in Platelet Biology |
Q41880057 | Activation of calpains mediates early lung neutrophilic inflammation in ventilator-induced lung injury |
Q37990195 | All cut up! The consequences of calpain activation on platelet function |
Q34213253 | Calpain 1 knockdown improves tissue sparing and functional outcomes after spinal cord injury in rats |
Q35939817 | Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma |
Q35157505 | Calpain chronicle--an enzyme family under multidisciplinary characterization |
Q61810933 | Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets |
Q37857282 | Calpain inhibitors: a survey of compounds reported in the patent and scientific literature |
Q47666229 | Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease. |
Q47947432 | Contribution of calpain to myoglobin efflux from cardiomyocytes during ischaemia and after reperfusion in anaesthetized rats |
Q33991611 | Differences in the expression of chromosome 1 genes between lung telocytes and other cells: mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells and lymphocytes |
Q36832592 | Dual mechanism of integrin αIIbβ3 closure in procoagulant platelets |
Q36139930 | Gα13 Switch Region 2 Binds to the Talin Head Domain and Activates αIIbβ3 Integrin in Human Platelets |
Q41951212 | Insulin, insulin resistance, and platelet signaling in diabetes |
Q34675826 | Mechanism of down-regulation of RNA polymerase III-transcribed non-coding RNA genes in macrophages by Leishmania |
Q34785837 | Permissive and repulsive cues and signalling pathways of axonal outgrowth and regeneration |
Q28546748 | Platelet mechanosensing of collagen matrices |
Q39893258 | TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration |
Q37798968 | The role of calpain in diabetes-associated platelet hyperactivation. |
Q49830459 | Vesicle-based secretion in schistosomes: Analysis of protein and microRNA (miRNA) content of exosome-like vesicles derived from Schistosoma mansoni |
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