scholarly article | Q13442814 |
P2093 | author name string | B C Furie | |
B Furie | |||
D A Potter | |||
I M Herman | |||
R Flaumenhaft | |||
K Croce | |||
M Rivers | |||
P2860 | cites work | A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments | Q24309448 |
Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons | Q24682526 | ||
Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets | Q28235484 | ||
Purification and characterization of an alpha 1 beta 2 isoform of CapZ from human erythrocytes: cytosolic location and inability to bind to Mg2+ ghosts suggest that erythrocyte actin filaments are capped by adducin | Q28253307 | ||
Inhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin gene | Q28254525 | ||
Calpain Cleavage of the Cytoplasmic Domain of the Integrin β2 Subunit | Q28291851 | ||
Beta cap73: a novel beta actin-specific binding protein | Q28296489 | ||
Regulation of cell migration by the calcium-dependent protease calpain | Q29391186 | ||
The endogenous lectin of human platelets is an alpha-granule component | Q70788259 | ||
Involvement of calpain in integrin-mediated signal transduction | Q71097810 | ||
A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets | Q71430992 | ||
Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin alphaIIbbeta3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots | Q71984999 | ||
Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets | Q72033892 | ||
pp60src is an endogenous substrate for calpain in human blood platelets | Q72083293 | ||
Mechanism of shape change in chilled human platelets | Q72126140 | ||
Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1 | Q72175900 | ||
Membrane binding properties of the factor IX gamma-carboxyglutamic acid-rich domain prepared by chemical synthesis | Q72724316 | ||
Domain structure of calpain: mapping the binding site for calpastatin | Q72773438 | ||
Proteolysis of synaptobrevin, syntaxin, and SNAP-25 in alveolar epithelial type II cells | Q73347983 | ||
An antisense oligodeoxyribonucleotide to m-calpain mRNA inhibits secretion from alveolar epithelial type II cells | Q74239800 | ||
Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4 | Q77801139 | ||
Calpain-catalyzed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets. | Q34070941 | ||
Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts | Q34301673 | ||
Biphasic activation of PKBalpha/Akt in platelets. Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced via a novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate | Q34466007 | ||
Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion | Q35875535 | ||
The cleaved peptide of the thrombin receptor is a strong platelet agonist | Q35979576 | ||
Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa | Q36233149 | ||
Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides | Q36237502 | ||
Calmodulin-binding domain of recombinant erythrocyte beta-adducin | Q36242358 | ||
Calpain regulates actin remodeling during cell spreading | Q36255313 | ||
Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3 | Q36256128 | ||
Role of calpain in skeletal-muscle protein degradation | Q36517553 | ||
Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence | Q36707669 | ||
Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potential | Q36792198 | ||
Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs | Q37270758 | ||
Calcium-activated neutral protease (calpain) system: structure, function, and regulation | Q37767409 | ||
Inhibition of secretion from isolated rat alveolar epithelial type II cells by the cell permeant calpain inhibitor II (N-acetyl-leucyl-leucyl-methioninal) | Q41671897 | ||
Inhibition of protein degradation in isolated rat hepatocytes | Q41980490 | ||
Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity | Q42053540 | ||
Investigation of the role of calpain as a stimulus-response mediator in human platelets using new synthetic inhibitors | Q42153402 | ||
Affinity labelling of the Ca(2+)-activated neutral proteinase (calpain) in intact human platelets | Q42796434 | ||
Role of the nuclear localization sequence in fibroblast growth factor-1-stimulated mitogenic pathways | Q42815473 | ||
LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain | Q42837762 | ||
Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain | Q42983314 | ||
Identification of two protease inhibitors from bovine cardiac muscle | Q44178959 | ||
Spectrin is associated with membrane-bound actin filaments in platelets and is hydrolyzed by the Ca2+-dependent protease during platelet activation | Q44227887 | ||
The occurrence of an inhibitor of Ca2+-dependent neutral protease in rat liver | Q45215140 | ||
Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin | Q46081423 | ||
Intracellular Ca2+-dependent protease (CALPAIN) and its high-molecular-weight endogenous inhibitor (CALPASTATIN) | Q47301366 | ||
A high molecular weight inhibitor of Ca2+-dependent neutral protease in rat brain | Q47305358 | ||
Adducin preferentially recruits spectrin to the fast growing ends of actin filaments in a complex requiring the MARCKS-related domain and a newly defined oligomerization domain. | Q47827809 | ||
Calpain: a protease in search of a function? | Q47923112 | ||
Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases | Q49133536 | ||
Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain. | Q54106494 | ||
Identification and characterization of inhibitory sequences in four repeating domains of the endogenous inhibitor for calcium-dependent protease. | Q54726844 | ||
Ionophore a 23187: some effects on platelet aggregation and clot retraction | Q67498837 | ||
Secretagogue-induced proteolysis of lung spectrin in alveolar epithelial type II cells | Q67571148 | ||
Ca2+-dependent protease in human platelets. Specific cleavage of platelet polypeptides in the presence of added Ca2+ | Q67600371 | ||
Membrane expression of platelet calpain | Q68723158 | ||
Rapid effects of phorbol ester on platelet shape change, cytoskeleton and calcium transient | Q69617612 | ||
Analysis of structure-function relationship of pig calpastatin by expression of mutated cDNAs in Escherichia coli | Q69831958 | ||
Calcium-dependent proteolysis occurs during platelet aggregation | Q70158655 | ||
Human platelet calmodulin-binding proteins: identification and Ca2+-dependent proteolysis upon platelet activation | Q70348098 | ||
In situ capture of mu-calpain activation in platelets | Q70636074 | ||
pH-dependent nonlysosomal proteolysis contributes to lethal anoxic injury of rat hepatocytes | Q70666379 | ||
P433 | issue | 51 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 7 | |
P304 | page(s) | 36321-36327 | |
P577 | publication date | 1999-12-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Inhibition of calpain blocks platelet secretion, aggregation, and spreading | |
P478 | volume | 274 |
Q24603193 | Actin dynamics in platelets |
Q37990195 | All cut up! The consequences of calpain activation on platelet function |
Q36785451 | Association between type 2 diabetes mellitus, biochemical factors and UCSNP-43 polymorphisms of CALPIN-10 gene in patients with atherosclerosis of coronary artery disease in Southern Iran population |
Q35079180 | Calpain activator dibucaine induces platelet apoptosis |
Q44140863 | Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells. |
Q38979394 | Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli |
Q36242090 | Calpain proteases in cell adhesion and motility |
Q33657916 | Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness |
Q38161548 | Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future? |
Q36783478 | Calpain-mediated regulation of platelet signaling pathways |
Q40652159 | Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: enhancing cell permeability by conjugation with penetratin. |
Q42668393 | Calpastatin subdomains A and C are activators of calpain |
Q30550030 | Ca²⁺ and calpain control membrane expansion during the rapid cell spreading of neutrophils. |
Q41616336 | Comparison of the protein expression of calpain-1, calpain-2, calpastatin and calmodulin between gastric cancer and normal gastric mucosa |
Q47947432 | Contribution of calpain to myoglobin efflux from cardiomyocytes during ischaemia and after reperfusion in anaesthetized rats |
Q45868733 | Coordinated control of both insulin secretion and insulin action through calpain-10-mediated regulation of exocytosis? |
Q36323239 | Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling |
Q34537620 | Cutting to the chase: calpain proteases in cell motility |
Q33967742 | Disruption of the mouse mu-calpain gene reveals an essential role in platelet function |
Q35950307 | Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets |
Q36342597 | Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active |
Q43830350 | Genetic variation of the platelet- surface integrin GPIIb-IIIa (PIA1/A2-SNP) shows a high association with Type 2 diabetes mellitus |
Q34997206 | Global analysis of the rat and human platelet proteome - the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution. |
Q40576080 | Human platelet 20S proteasome: inhibition of its chymotrypsin-like activity and identification of the proteasome activator PA28. A preliminary report |
Q41970355 | Inhibit the calpain to climb the mountain |
Q46398330 | Inhibition of calpain blocks pancreatic beta-cell spreading and insulin secretion |
Q22001543 | Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum |
Q64056707 | Intercellular Vesicular Transfer by Exosomes, Microparticles and Oncosomes - Implications for Cancer Biology and Treatments |
Q30300686 | Involvement of calpains in adult neurogenesis: implications for stroke |
Q36890791 | Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging |
Q91595903 | Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome |
Q44055431 | Melatonin elevates intracellular free calcium in human platelets by inositol 1,4,5-trisphosphate independent mechanism |
Q73372406 | Molecular Basis of Platelet Granule Secretion |
Q47071712 | Molecular cloning and RNA expression of a novel Drosophila calpain, Calpain C. |
Q40599716 | Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization. |
Q90484536 | Procoagulant Phosphatidylserine-Exposing Platelets in vitro and in vivo |
Q27693902 | Protein degradation systems in platelets |
Q34168003 | Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion |
Q46427353 | Proteolysis leads to the appearance of the long form of beta3-endonexin in human platelets |
Q40603207 | Receptor/transporter-independent targeting of functional peptides across the plasma membrane |
Q37279026 | Replication of calpain-10 genetic association with carotid intima-media thickness |
Q35989495 | SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane |
Q30711945 | SNAP-23 is a target for calpain cleavage in activated platelets. |
Q51313041 | Sitagliptin: anti-platelet effect in diabetes and healthy volunteers. |
Q37641872 | Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading |
Q37798968 | The role of calpain in diabetes-associated platelet hyperactivation. |
Q42518733 | Thiosulfinates modulate platelet activation by reaction with surface free sulfhydryls and internal thiol-containing proteins. |
Q44272977 | Thrombotic microangiopathy in blood and marrow transplant patients receiving tacrolimus or cyclosporine A. |
Q36074745 | Two-wavelength near-infrared fluorescence for the quantitation of drug antiplatelet effects in large animal model systems |
Q44965408 | Vinculin is proteolyzed by calpain during platelet aggregation: 95 kDa cleavage fragment associates with the platelet cytoskeleton. |
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