Holocentromeres are dispersed point centromeres localized at transcription factor hotspots

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Holocentromeres are dispersed point centromeres localized at transcription factor hotspots is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.02025
P932PMC publication ID3975580
P698PubMed publication ID24714495

P50authorFlorian A SteinerQ56489551
Steven HenikoffQ28033746
P2860cites workInduced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomesQ24300684
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tensionQ24304199
Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeresQ24654940
Functional analysis of kinetochore assembly in Caenorhabditis elegans.Q24679016
Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatinQ24683353
The unconventional structure of centromeric nucleosomesQ26865376
Histone H3.3 variant dynamics in the germline of Caenorhabditis elegansQ27315564
A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-CQ27678426
Genome sequence of the nematode C. elegans: a platform for investigating biologyQ27860527
Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequencesQ27860707
Chromatin particle spectrum analysis: a method for comparative chromatin structure analysis using paired-end mode next-generation DNA sequencing.Q27935311
Cse4 is part of an octameric nucleosome in budding yeastQ27939957
HCP-4, a CENP-C-like protein in Caenorhabditis elegans, is required for resolution of sister centromeresQ36364884
An inverse relationship to germline transcription defines centromeric chromatin in C. elegansQ36511978
The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assemblyQ36525667
The chromatin structure of centromeres from fission yeast: differentiation of the central core that correlates with functionQ36529127
In vivo genomic footprint of a yeast centromereQ36679998
The landscape of RNA polymerase II transcription initiation in C. elegans reveals promoter and enhancer architecturesQ37061192
The CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeresQ37395247
Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis.Q38024240
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histonesQ38343707
Mislocalization of the centromeric histone variant CenH3/CENP-A in human cells depends on the chaperone DAXX.Q39023712
A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromereQ40241250
MyoD and myogenesis in C. elegans.Q40524034
Extrachromosomal DNA transformation of Caenorhabditis elegansQ40676581
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signatureQ41766976
HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytesQ41963250
"Point" centromeres of Saccharomyces harbor single centromere-specific nucleosomesQ42561272
A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networksQ43251350
A histone-H3-like protein in C. elegansQ47068912
Major evolutionary transitions in centromere complexity.Q51613870
Genome-scale profiling of histone H3.3 replacement patterns.Q52660778
CENP-C is a structural platform for kinetochore assembly.Q52716239
CENP-A-containing nucleosomes: easier disassembly versus exclusive centromeric localization.Q53550799
The kinetochores of Caenorhabditis elegansQ70598101
Distinct factors control histone variant H3.3 localization at specific genomic regionsQ28275277
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE projectQ28301622
Tetrameric structure of centromeric nucleosomes in interphase Drosophila cellsQ28469268
MEME SUITE: tools for motif discovery and searchingQ29547204
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assemblyQ29618256
Efficient yeast ChIP-Seq using multiplex short-read DNA sequencingQ33401685
Partitioning the C. elegans genome by nucleosome modification, occupancy, and positioningQ33587754
A native chromatin purification system for epigenomic profiling in Caenorhabditis elegansQ33700093
Perinuclear P granules are the principal sites of mRNA export in adult C. elegans germ cellsQ33761242
Dual recognition of CENP-A nucleosomes is required for centromere assemblyQ33950286
Epigenome characterization at single base-pair resolution.Q34057123
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres.Q34333350
The octamer is the major form of CENP-A nucleosomes at human centromeresQ34342975
Overlapping Regulation of CenH3 Localization and Histone H3 Turnover by CAF-1 and HIR Proteins in Saccharomyces cerevisiaeQ34477448
Broad chromosomal domains of histone modification patterns in C. elegansQ34548272
Centromere-like regions in the budding yeast genomeQ34561899
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegansQ34625961
Isolation of a yeast centromere and construction of functional small circular chromosomesQ34714350
Neocentromeres: new insights into centromere structure, disease development, and karyotype evolutionQ34746589
Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA bindingQ34807363
Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres.Q34989114
Hotspots of transcription factor colocalization in the genome of Drosophila melanogasterQ35033165
Heat shock reduces stalled RNA polymerase II and nucleosome turnover genome-wideQ35569664
Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryosQ35645091
Tripartite organization of centromeric chromatin in budding yeastQ35657537
Nucleosome stability mediated by histone variants H3.3 and H2A.Z.Q35840889
Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling.Q35864744
Centromere identity is specified by a single centromeric nucleosome in budding yeastQ35990276
Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegansQ36324773
P407language of work or nameEnglishQ1860
P304page(s)e02025
P577publication date2014-01-01
P1433published ineLifeQ2000008
P1476titleHolocentromeres are dispersed point centromeres localized at transcription factor hotspots
P478volume3

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cites work (P2860)
Q90720382"Lessons from the extremes: Epigenetic and genetic regulation in point monocentromere and holocentromere establishment on artificial chromosomes"
Q38765635A Molecular View of Kinetochore Assembly and Function
Q35540372A unique chromatin complex occupies young α-satellite arrays of human centromeres
Q26866535Atypical centromeres in plants-what they can tell us
Q48364377CENP-A and topoisomerase-II antagonistically affect chromosome length.
Q35186792CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells
Q41338613CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers
Q39042190Cell Biology of the Caenorhabditis elegans Nucleus
Q56866576Centromere and Kinetochore: Essential Components for Chromosome Segregation
Q60938313Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health
Q64957535Chromatin Compaction by Small RNAs and the Nuclear RNAi Machinery in C. elegans.
Q26799305Chromatin Dynamics in Vivo: A Game of Musical Chairs
Q39110341Chromatin dynamics during the cell cycle at centromeres
Q36627878DNA deletion as a mechanism for developmentally programmed centromere loss.
Q58115527Determinants of promoter and enhancer transcription directionality in metazoans
Q39469348Differential Chromosomal Localization of Centromeric Histone CENP-A Contributes to Nematode Programmed DNA Elimination
Q55264064Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response in Caenorhabditis elegans.
Q99614893Epigenetic Mechanisms of Learning and Memory: Implications for Aging
Q37022622Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?
Q26767470GIP Contributions to the Regulation of Centromere at the Interface Between the Nuclear Envelope and the Nucleoplasm
Q64923274H3.3K27M-induced chromatin changes drive ectopic replication through misregulation of the JNK pathway in C. elegans.
Q36676559H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans
Q35799797High evolutionary turnover of satellite families in Caenorhabditis.
Q52589500Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-AHCP-3 Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes.
Q38928957Holocentromere identity: from the typical mitotic linear structure to the great plasticity of meiotic holocentromeres.
Q36268643Holocentromeres in Rhynchospora are associated with genome-wide centromere-specific repeat arrays interspersed among euchromatin.
Q36132266Inner Kinetochore Protein Interactions with Regional Centromeres of Fission Yeast
Q26775369Insights into epigenetic landscape of recombination-free regions
Q90226328Isolation of a Pericentromeric Satellite DNA Family in Chnootriba argus (Henosepilachna argus) with an Unusual Short Repeat Unit (TTAAAA) for Beetles
Q90159956Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages
Q47192170Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis.
Q38355891Recent advances in plant centromere biology
Q35176510Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects
Q33364777Regulation of Plant Cellular and Organismal Development by SUMO.
Q41673553Satellite DNA: An Evolving Topic
Q34465647Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin.
Q36071249Stable Patterns of CENH3 Occupancy Through Maize Lineages Containing Genetically Similar Centromeres
Q34526452The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes
Q35882309The Genetic Map Enters Its Second Century
Q34160736The centromere: chromatin foundation for the kinetochore machinery
Q53477429The ultrastructure of mono- and holocentric plant centromeres: an immunological investigation by structured illumination microscopy and scanning electron microscopy.
Q90374454Understanding eukaryotic chromosome segregation from a comparative biology perspective
Q89610613What makes a centromere?

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