Abstract is: Steven Henikoff is a scientist at the Fred Hutchinson Cancer Research Center, and an HHMI Investigator. His field of study is chromatin-related transcriptional regulation. He earned his BS in chemistry at the University of Chicago. He earned his PhD in biochemistry and molecular biology from Harvard University in the lab of Matt Meselson in 1977. He did a postdoctoral fellowship at the University of Washington. His research has been funded by the National Science Foundation, National Institutes of Health, and HHMI. In 1992, Steven Henikoff, together with his wife Jorja Henikoff, introduced the BLOSUM substitution matrices. The BLOSUM matrices are widely used for sequence alignment of proteins. In 2005, Henikoff was elected to the National Academy of Sciences.
human | Q5 |
P2381 | Academic Tree ID | 14226 |
P2456 | DBLP author ID | 65/5756 |
P6178 | Dimensions author ID | 01110332674.32 |
P2671 | Google Knowledge Graph ID | /g/11c2kh81qf |
P244 | Library of Congress authority ID | n2015180265 |
P5380 | National Academy of Sciences member ID | 20010000 |
P8189 | National Library of Israel J9U ID | 987007343248105171 |
P496 | ORCID iD | 0000-0002-7621-8685 |
P10861 | Springer Nature person ID | 01110332674.32 |
P214 | VIAF ID | 313491528 |
P10832 | WorldCat Entities ID | E39PBJtGVQy9YdGtxRBCfjcF8C |
P512 | academic degree | Doctor of Philosophy | Q752297 |
P166 | award received | Genetics Society of America Medal | Q980337 |
Fellow of the American Association for the Advancement of Science | Q5442484 | ||
Fellow of the American Academy of Arts and Sciences | Q52382875 | ||
P27 | country of citizenship | United States of America | Q30 |
P1343 | described by source | Profile of Steven Henikoff | Q34725011 |
P69 | educated at | Harvard University | Q13371 |
University of Chicago | Q131252 | ||
P108 | employer | Fred Hutchinson Cancer Research Center | Q1452369 |
Howard Hughes Medical Institute | Q1512226 | ||
P101 | field of work | biochemistry | Q7094 |
P735 | given name | Steven | Q17501985 |
Steven | Q17501985 | ||
P463 | member of | National Academy of Sciences | Q270794 |
P106 | occupation | researcher | Q1650915 |
biochemist | Q2919046 | ||
P21 | sex or gender | male | Q6581097 |
Q42561272 | "Point" centromeres of Saccharomyces harbor single centromere-specific nucleosomes |
Q33525010 | A comprehensive map of insulator elements for the Drosophila genome |
Q33700093 | A native chromatin purification system for epigenomic profiling in Caenorhabditis elegans |
Q34000729 | A simple method for gene expression and chromatin profiling of individual cell types within a tissue |
Q30426389 | A unified phylogeny-based nomenclature for histone variants |
Q35540372 | A unique chromatin complex occupies young α-satellite arrays of human centromeres |
Q24794896 | Adaptive evolution of centromere proteins in plants and animals |
Q37643706 | An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites |
Q36280301 | Assembly of variant histones into chromatin |
Q112287732 | Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia |
Q24804292 | Automated band mapping in electrophoretic gel images using background information |
Q60938025 | Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs |
Q104573966 | Biparental contributions of the H2A.B histone variant control embryonic development in mice |
Q47190846 | CENP-A octamers do not confer a reduction in nucleosome height by AFM. |
Q35207595 | CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primer) PCR primer design |
Q64081920 | CUT&Tag for efficient epigenomic profiling of small samples and single cells |
Q30238731 | Capitalizing on disaster: Establishing chromatin specificity behind the replication fork |
Q35864744 | Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling. |
Q33540995 | Centromeres convert but don't cross |
Q48301632 | Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. |
Q34153617 | Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis |
Q92533688 | Chromatin Bottlenecks in Cancer |
Q24813673 | Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis |
Q34617267 | Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres |
Q34459733 | Chromatin roadblocks to reprogramming 50 years on. |
Q47875520 | Chromatin-based transcriptional punctuation |
Q34318835 | Chromatin: packaging without nucleosomes |
Q45236570 | DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes |
Q33281829 | Discovery of chemically induced mutations in rice by TILLING. |
Q24800006 | Discovery of induced point mutations in maize genes by TILLING |
Q33589879 | Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location |
Q34039414 | Doxorubicin, DNA torsion, and chromatin dynamics |
Q102064474 | Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation |
Q34296952 | Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. |
Q99350094 | Efficient low-cost chromatin profiling with CUT&Tag |
Q38242551 | Environmental responses mediated by histone variants |
Q34157982 | Epigenetic consequences of nucleosome dynamics |
Q34057123 | Epigenome characterization at single base-pair resolution. |
Q123557184 | Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag |
Q90316153 | EvoChromo: towards a synthesis of chromatin biology and evolution |
Q89877161 | Evolution: Heterochromatin Diversity in Early-Branching Land Plants |
Q33394752 | Fly-TILL: reverse genetics using a living point mutation resource |
Q52660778 | Genome-scale profiling of histone H3.3 replacement patterns. |
Q38343707 | Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones |
Q77486342 | Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3 |
Q37142037 | Genome-wide profiling of salt fractions maps physical properties of chromatin |
Q34000004 | Genomic analysis of parent-of-origin allelic expression in Arabidopsis thaliana seeds |
Q112647397 | Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations |
Q34637938 | H2A.Z nucleosomes enriched over active genes are homotypic |
Q39208908 | High-resolution mapping defines the cooperative architecture of Polycomb response elements |
Q37593221 | High-resolution mapping of transcription factor binding sites on native chromatin |
Q53620190 | High-throughput TILLING for Arabidopsis. |
Q44591078 | High-throughput TILLING for functional genomics. |
Q33371693 | Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks |
Q34444033 | Histone H3 variants specify modes of chromatin assembly |
Q33196967 | Histone H3.3 is enriched in covalent modifications associated with active chromatin |
Q27315564 | Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans |
Q99236140 | Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones |
Q33936701 | Histone modifications: combinatorial complexity or cumulative simplicity? |
Q38303903 | Histone replacement marks the boundaries of cis-regulatory domains |
Q30301007 | Histone variants and epigenetics |
Q34347268 | Histone variants in pluripotency and disease |
Q39031041 | Histone variants on the move: substrates for chromatin dynamics |
Q35818464 | Histone variants, nucleosome assembly and epigenetic inheritance |
Q28274796 | Histone variants--ancient wrap artists of the epigenome |
Q33588109 | Histone variants: dynamic punctuation in transcription |
Q34414322 | Holocentromeres are dispersed point centromeres localized at transcription factor hotspots |
Q27931272 | ISWI and CHD chromatin remodelers bind promoters but act in gene bodies |
Q83232258 | Improved CUT&RUN chromatin profiling tools |
Q36132266 | Inner Kinetochore Protein Interactions with Regional Centromeres of Fission Yeast |
Q28301622 | Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project |
Q33391509 | Intergenic locations of rice centromeric chromatin |
Q34999257 | Large-scale discovery of induced point mutations with high-throughput TILLING. |
Q35145809 | Maintenance of chromatin states: an open-and-shut case |
Q76371022 | Maize centromeres: organization and functional adaptation in the genetic background of oat |
Q35541535 | Mapping regulatory factors by immunoprecipitation from native chromatin |
Q34396847 | Measuring genome-wide nucleosome turnover using CATCH-IT. |
Q34327561 | Mismatch cleavage by single-strand specific nucleases |
Q91823317 | No strand left behind |
Q90068390 | Nucleosomes remember where they were |
Q92461157 | Old cogs, new tricks: the evolution of gene expression in a chromatin context |
Q91835818 | Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling |
Q47958040 | Phylogeny as the basis for naming histones |
Q72643969 | Position-effect variegation and chromosome structure of a heat shock puff in Drosophila |
Q24811626 | Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila |
Q24814659 | Positive selection of Iris, a retroviral envelope-derived host gene in Drosophila melanogaster |
Q49538593 | Precise genome-wide mapping of single nucleosomes and linkers in vivo. |
Q28250660 | Predicting the effects of amino acid substitutions on protein function |
Q95607891 | Profiling the epigenome at home |
Q90098516 | Quantitative MNase-seq accurately maps nucleosome occupancy levels |
Q30453733 | Reconstitution of hemisomes on budding yeast centromeric DNA. |
Q34009740 | Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone |
Q28286686 | Regulation of nucleosome dynamics by histone modifications |
Q49354936 | Remarkable Evolutionary Plasticity of Centromeric Chromatin. |
Q36873820 | Retention of induced mutations in a Drosophila reverse-genetic resource |
Q34106253 | Salt fractionation of nucleosomes for genome-wide profiling |
Q24540226 | Self-perpetuating structural states in biology, disease, and genetics |
Q40490218 | Sequence of aDrosophilaDNA segment that functions inSaccharomyces Cerevisiaeand its regulation by a yeast promoter |
Q34289102 | Sequencing of a rice centromere uncovers active genes |
Q112299179 | Short H2A histone variants are expressed in cancer |
Q24791068 | Silencing of transposons in plant genomes: kick them when they're down |
Q47228653 | Simple and Complex Centromeric Satellites in Drosophila Sibling Species |
Q52714951 | Simultaneous Discovery of Cell-Free DNA and the Nucleosome Ladder. |
Q112719574 | Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression |
Q34617887 | Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. |
Q34567039 | Spreading of silent chromatin: inaction at a distance |
Q33316413 | TILLING to detect induced mutations in soybean. |
Q52719687 | Targeted in situ genome-wide profiling with high efficiency for low cell numbers. |
Q30752290 | Tech.Sight. Phage display. Affinity selection from biological libraries |
Q28469268 | Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells |
Q37395247 | The CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres |
Q112644559 | The H3.3K27M oncohistone antagonizes reprogramming in Drosophila |
Q37698353 | The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo |
Q29617486 | The epigenetic progenitor origin of human cancer |
Q112580053 | The structure of a virus-encoded nucleosome |
Q26865376 | The unconventional structure of centromeric nucleosomes |
Q103028179 | Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome |
Q88999598 | Transcribing Centromeres: Noncoding RNAs and Kinetochore Assembly |
Q47335256 | Transcription and Remodeling Produce Asymmetrically Unwrapped Nucleosomal Intermediates. |
Q53650265 | Transcription and histone modifications in the recombination-free region spanning a rice centromere. |
Q41327335 | Transcription at two heat shock loci in Drosophila |
Q52518924 | Transcription terminates in yeast distal to a control sequence |
Q35657537 | Tripartite organization of centromeric chromatin in budding yeast |
Q48131224 | Unexpected conformational variations of the human centromeric chromatin complex |
Q27860941 | Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing |
Q33745487 | Unlocking the secrets of the genome |
Q51869167 | Using the blocks database to recognize functional domains. |
Q89610613 | What makes a centromere? |
Steven Henikoff | wikipedia | |
Хеникофф, Стивен | wikipedia | |
史蒂文·赫尼科夫 | wikipedia |
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