Unlocking the secrets of the genome

scientific article

Unlocking the secrets of the genome is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1043448162
P356DOI10.1038/459927A
P932PMC publication ID2843545
P698PubMed publication ID19536255
P5875ResearchGate publication ID26301182

P50authorLincoln SteinQ6551037
Mark Bender GersteinQ6766711
Steven RussellQ42277880
Eric C LaiQ52431492
Susan E. CelnikerQ64871649
Gary H. KarpenQ64871727
Jason D LiebQ109084133
Steven HenikoffQ28033746
Manolis KellisQ28050827
Michael P. SnyderQ28924918
Gos MicklemQ30347699
P2093author name stringKevin P White
David M MacAlpine
Fabio Piano
Robert H Waterston
Kristin C Gunsalus
Laura A L Dillon
modENCODE Consortium
P2860cites workIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomicsQ21092840
Evolution of genes and genomes on the Drosophila phylogenyQ22122220
Genome-wide detection and characterization of positive selection in human populationsQ23000444
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genesQ34645019
Discovery of functional elements in 12 Drosophila genomes using evolutionary signaturesQ34712340
Global analysis of patterns of gene expression during Drosophila embryogenesisQ36570645
Drosophila melanogaster neurobiology, neuropharmacology, and how the fly can inform central nervous system drug discoveryQ36578581
Exploring genetic interactions and networks with yeastQ36825599
A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networksQ43251350
Tissue-specific gene expression and ecdysone-regulated genomic networks in DrosophilaQ44507969
Biological function of unannotated transcription during the early development of Drosophila melanogasterQ46858945
Genome-wide germline-enriched and sex-biased expression profiles in Caenorhabditis elegansQ47327774
Whole-genome sequencing and variant discovery in C. elegans.Q47595683
A gene expression map for Caenorhabditis elegans.Q48342750
A gene expression map for the euchromatic genome of Drosophila melanogaster.Q51985912
Gene expression during the life cycle of Drosophila melanogaster.Q52031678
Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome.Q52110050
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesQ24647928
The generic genome browser: a building block for a model organism system databaseQ24682395
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAsQ24684603
Systematic determination of patterns of gene expression during Drosophila embryogenesisQ24803813
Systematic functional analysis of the Caenorhabditis elegans genome using RNAiQ27860839
Large-scale analysis of the yeast genome by transposon tagging and gene disruptionQ27929503
A genome-wide transgenic RNAi library for conditional gene inactivation in DrosophilaQ28236209
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi libraryQ28770084
The ENCODE (ENCyclopedia Of DNA Elements) ProjectQ29547219
A gene-coexpression network for global discovery of conserved genetic modulesQ29614451
Using FlyAtlas to identify better Drosophila melanogaster models of human diseaseQ29615721
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegansQ29616062
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegansQ29618013
Identification of putative noncoding polyadenylated transcripts in Drosophila melanogasterQ33935782
The Drosophila melanogaster genomeQ33972954
Genome-wide RNAi analysis of growth and viability in Drosophila cellsQ34295039
Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegansQ34591276
P433issue7249
P407language of work or nameEnglishQ1860
P304page(s)927-930
P577publication date2009-06-01
P1433published inNatureQ180445
P1476titleUnlocking the secrets of the genome
P478volume459

Reverse relations

cites work (P2860)
Q89578330"What You Need, Baby, I Got It": Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila
Q90318376*-DCC: A platform to collect, annotate, and explore a large variety of sequencing experiments
Q587013854C-seq characterization of Drosophila BEAF binding regions provides evidence for highly variable long-distance interactions between active chromatin
Q33675100A Drosophila model for developmental nicotine exposure
Q55027027A Fly's Eye View of Natural and Drug Reward.
Q47412025A Moving Source of Matrix Components Is Essential for De Novo Basement Membrane Formation
Q37629287A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans
Q27323959A conserved upstream motif orchestrates autonomous, germline-enriched expression of Caenorhabditis elegans piRNAs
Q35749763A convex formulation for joint RNA isoform detection and quantification from multiple RNA-seq samples
Q38655263A genome-scale resource for in vivo tag-based protein function exploration in C. elegans
Q34548280A global analysis of C. elegans trans-splicing
Q110950126A machine learning framework for the prediction of chromatin folding in using epigenetic features
Q52716890A modENCODE snapshot.
Q33879802A novel dataset for identifying sex-biased genes in Drosophila
Q35975052A novel statistical method for quantitative comparison of multiple ChIP-seq datasets
Q37345828A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans.
Q30486696A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Q34078493A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunits
Q90911003A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing
Q64246947A splice-site variant in the lncRNA gene cosegregates in the large Volkmann cataract family
Q28305422A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets
Q41791001A synthetic biology approach to the development of transcriptional regulatory models and custom enhancer design
Q45979863A user-friendly chromatographic method to purify small regulatory RNAs.
Q34249593A view through a chromatin loop: insights into the ecdysone activation of early genes in Drosophila
Q33829467ACT: aggregation and correlation toolbox for analyses of genome tracks.
Q31115851AGOUTI: improving genome assembly and annotation using transcriptome data
Q64074763ATAC-seq reveals regional differences in enhancer accessibility during the establishment of spatial coordinates in the blastoderm
Q36069619ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation
Q35998452Abnormal Osmotic Avoidance Behavior in C. elegans Is Associated with Increased Hypertonic Stress Resistance and Improved Proteostasis
Q47652803Accounting for GC-content bias reduces systematic errors and batch effects in ChIP-seq data
Q27321750Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains
Q92227197Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei
Q33934389Adaptive impact of the chimeric gene Quetzalcoatl in Drosophila melanogaster
Q34187034Akirin links twist-regulated transcription with the Brahma chromatin remodeling complex during embryogenesis
Q37747079Alcohol-Induced Neuroadaptation Is Orchestrated by the Histone Acetyltransferase CBP
Q28536909Alcohol-induced histone acetylation reveals a gene network involved in alcohol tolerance
Q37789529Allele-specific and heritable chromatin signatures in humans
Q58084814Allele-specific expression elucidates cis-regulatory logic
Q34276467Altering the sex determination pathway in Drosophila fat body modifies sex-specific stress responses
Q37485704An RNAi Screen To Identify Protein Phosphatases That Function Within the Drosophila Circadian Clock.
Q36951875An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1.
Q34472347An assessment of histone-modification antibody quality
Q35603451An automated method for efficient, accurate and reproducible construction of RNA-seq libraries
Q34981252An epigenetic signature for monoallelic olfactory receptor expression
Q36106993Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq
Q37948799Analysis of primary structure of chromatin with next-generation sequencing
Q37623113Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals
Q34023095Annotating non-coding regions of the genome
Q64110537Applications of ENCODE data to Systematic Analyses via Data Integration
Q41901963ArchAlign: coordinate-free chromatin alignment reveals novel architectures
Q37228819Architectural proteins Pita, Zw5,and ZIPIC contain homodimerization domain and support specific long-range interactions in Drosophila
Q33769725Assessing computational methods of cis-regulatory module prediction
Q34633686Association mapping across numerous traits reveals patterns of functional variation in maize
Q64076214Association of Human Promoter Variants with the Occurrence of Knee-Osteoarthritis in a Case Control Association Study
Q38887794Atrophin controls developmental signaling pathways via interactions with Trithorax-like
Q41056167BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer
Q34671949Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence
Q35171653Base-resolution methylation patterns accurately predict transcription factor bindings in vivo
Q30000081Bayesian Correlation Analysis for Sequence Count Data
Q109443298BioHackathon series in 2013 and 2014: improvements of semantic interoperability in life science data and services
Q37069699Bioinformatic analyses of sense and antisense expression from terminal inverted repeat transposons in Drosophila somatic cells
Q47071403Blocking promiscuous activation at cryptic promoters directs cell type-specific gene expression
Q35809678CCDC-55 is required for larval development and distal tip cell migration in Caenorhabditis elegans
Q57902784CHRAC/ACF contribute to the repressive ground state of chromatin
Q37234055CardioTF, a database of deconstructing transcriptional circuits in the heart system
Q28271574Cell fate specification in the C. elegans embryo
Q33718807ChIP-Seq using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites
Q33831056ChIP-chip versus ChIP-seq: lessons for experimental design and data analysis.
Q31132639ChIP-seq Data Processing for PcG Proteins and Associated Histone Modifications.
Q28274448ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
Q29615336ChIP-seq: advantages and challenges of a maturing technology
Q39350879Challenges and progress in interpretation of non-coding genetic variants associated with human disease
Q47547405Chinmo prevents transformer alternative splicing to maintain male sex identity.
Q36051843Chromatin Heterogeneity and Distribution of Regulatory Elements in the Late-Replicating Intercalary Heterochromatin Domains of Drosophila melanogaster Chromosomes
Q21092435Chromatin Landscape Dictates HSF Binding to Target DNA Elements
Q38114411Chromatin and epigenetic features of long-range gene regulation
Q28071827Chromatin boundary elements organize genomic architecture and developmental gene regulation in Drosophila Hox clusters
Q57046190Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila
Q34548240Chromatin signatures of the Drosophila replication program
Q39346590Classification of Promoters Based on the Combination of Core Promoter Elements Exhibits Different Histone Modification Patterns.
Q34605602Clcn4-2 genomic structure differs between the X locus in Mus spretus and the autosomal locus in Mus musculus: AT motif enrichment on the X.
Q49595295Cloud computing for genomic data analysis and collaboration
Q28687107Cloud-based uniform ChIP-Seq processing tools for modENCODE and ENCODE
Q38708191Cohesin selectively binds and regulates genes with paused RNA polymerase
Q34791301Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans
Q37184686Combinatorial Gene Regulatory Functions Underlie Ultraconserved Elements in Drosophila
Q35017822Combinatorial chromatin modification patterns in the human genome revealed by subspace clustering.
Q39030399Combinatorial modeling of chromatin features quantitatively predicts DNA replication timing in Drosophila
Q48744343Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder.
Q37090555Comparative Expression Dynamics of Intergenic Long Noncoding RNAs in the Genus Drosophila
Q61531269Comparative Transcriptomics in Two Extreme Neopterans Reveals General Trends in the Evolution of Modern Insects
Q42375055Comparative analysis of miRNA expression during the development of insects of different metamorphosis modes and germ-band types
Q30834511Comparative validation of the D. melanogaster modENCODE transcriptome annotation.
Q33839404Comparison of D. melanogaster and C. elegans developmental stages, tissues, and cells by modENCODE RNA-seq data
Q41870191Competition within Introns: Splicing Wins over Polyadenylation via a General Mechanism
Q33797835Composite effects of polymorphisms near multiple regulatory elements create a major-effect QTL
Q35239284Comprehensive RNA-Seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats
Q34548301Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
Q28535025Computational identification of diverse mechanisms underlying transcription factor-DNA occupancy
Q35589989Condensin II Regulates Interphase Chromatin Organization Through the Mrg-Binding Motif of Cap-H2.
Q28652295Conservation of transcription factor binding specificities across 600 million years of bilateria evolution
Q34485051Conserved Catalytic and C-Terminal Regulatory Domains of the C-Terminal Binding Protein Corepressor Fine-Tune the Transcriptional Response in Development
Q35914970Conserved Motifs and Prediction of Regulatory Modules in Caenorhabditis elegans
Q35840926Considerations for creating and annotating the budding yeast Genome Map at SGD: a progress report
Q34085568Construction and analysis of an integrated regulatory network derived from high-throughput sequencing data
Q90665256Construction of a human cell landscape at single-cell level
Q42730926Coordinated expression of cell death genes regulates neuroblast apoptosis
Q27319972Coordination of cell proliferation and cell fate determination by CES-1 snail
Q39455041Copy number variation at 6q13 functions as a long-range regulator and is associated with pancreatic cancer risk
Q91975751Correlations Between LC-MS/MS-Detected Glycomics and NMR-Detected Metabolomics in Caenorhabditis elegans Development
Q36311097Correspondence of D. melanogaster and C. elegans developmental stages revealed by alternative splicing characteristics of conserved exons
Q36019786Coupling polymerase pausing and chromatin landscapes for precise regulation of transcription.
Q39525696CpG deamination creates transcription factor-binding sites with high efficiency
Q34803391CpG islands under selective pressure are enriched with H3K4me3, H3K27ac and H3K36me3 histone modifications
Q33988776CpG islands undermethylation in human genomic regions under selective pressure
Q36105392Cross-species Conservation of context-specific networks.
Q31098863DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data
Q43239268DNA methylation: Bidding the CpG island goodbye
Q92147261DNA sequence models of genome-wide Drosophila melanogaster Polycomb binding sites improve generalization to independent Polycomb Response Elements
Q36500344DNMT3L enables accumulation and inheritance of epimutations in transgenic Drosophila
Q28655601Data integration in the era of omics: current and future challenges
Q34695037De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets
Q37731441Deciphering the genome's regulatory code: the many languages of DNA.
Q28223334DeepChrome: deep-learning for predicting gene expression from histone modifications
Q48365068Deleterious Consequences of UDP-Galactopyranose Mutase Inhibition for Nematodes
Q27322323Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy
Q33938584Determinants of antigenicity and specificity in immune response for protein sequences
Q58115527Determinants of promoter and enhancer transcription directionality in metazoans
Q41578627Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster
Q29614411Discovery and characterization of chromatin states for systematic annotation of the human genome
Q37271106Discovery of cell-type specific regulatory elements in the human genome using differential chromatin modification analysis
Q34057105Distinct epigenomic features in end-stage failing human hearts
Q34625961Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans
Q36782151Don't pull the plug! the Drosophila mating plug preserves fertility
Q24613669DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila
Q36354873Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains
Q93072309Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenesis and wiring of neural circuits
Q61445262Drosophila ML-DmD17-c3 cells respond robustly to Dpp and exhibit complex transcriptional feedback on BMP signaling components
Q27320161Drosophila Ninjurin A induces nonapoptotic cell death
Q33618928Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading
Q40338111Drosophila RB proteins repress differentiation-specific genes via two different mechanisms
Q37900773Drosophila RNAi screening in a postgenomic world
Q28082964Drosophila sodium channel mutations: Contributions to seizure-susceptibility
Q34216750Drosophila, genetic screens, and cardiac function
Q47844892Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity.
Q33577722Dynamic regulation of genetic pathways and targets during aging in Caenorhabditis elegans
Q50933686EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila.
Q33516102ENCODE whole-genome data in the UCSC Genome Browser
Q24616384ENCODE whole-genome data in the UCSC genome browser (2011 update)
Q49980715Early experiences mediate distinct adult gene expression and reproductive programs in Caenorhabditis elegans
Q36781108Early-late genes of the ecdysone cascade as models for transcriptional studies.
Q34342135Ecdysone induced gene expression is associated with acetylation of histone H3 lysine 23 in Drosophila melanogaster
Q36574548Effects of DNA Methylation and Chromatin State on Rates of Molecular Evolution in Insects
Q34980545Efficient alignment of RNA secondary structures using sparse dynamic programming
Q37763940Elucidating gene regulatory mechanisms for sperm function through the integration of classical and systems approaches in C. elegans
Q35996008Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired
Q45712489Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.
Q37013090Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin
Q34683257Enrichment of mRNA-like noncoding RNAs in the divergence of Drosophila males.
Q58580316Epidermal Remodeling in Dauers Requires the Nidogen Domain Protein DEX-1
Q37961801Epigenetic control of inducible gene expression in the immune system.
Q34210736Epigenetic features are significantly associated with alternative splicing
Q34618183Epigenomic plasticity within populations: its evolutionary significance and potential.
Q58580309Epithelial Shaping by Diverse Apical Extracellular Matrices Requires the Nidogen Domain Protein DEX-1 in
Q41809122Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis.
Q33618555Estimating enrichment of repetitive elements from high-throughput sequence data
Q49859624Evidence for a hierarchical transcriptional circuit in Drosophila male germline involving testis-specific TAF and two gene-specific transcription factors, Mod and Acj6.
Q34443568Evidence for deep regulatory similarities in early developmental programs across highly diverged insects
Q39575714Evolution of a tissue-specific splicing network
Q37661352Evolution of an epigenetic gene ensemble within the genus Anopheles
Q34386956Evolution of the Drosophila Feminizing Switch Gene Sex-lethal
Q46917962Evolution under monogamy feminizes gene expression in Drosophila melanogaster
Q29615083Expansion of the eukaryotic proteome by alternative splicing
Q47648708Extracellular NME proteins: a player or a bystander?
Q36474425Fife, a Drosophila Piccolo-RIM homolog, promotes active zone organization and neurotransmitter release
Q50487328Fine-tuning of chromatin composition and Polycomb recruitment by two Mi2 homologues during C. elegans early embryonic development
Q35253618FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations
Q38699363FlyExpress 7: An Integrated Discovery Platform To Study Coexpressed Genes Using in Situ Hybridization Images in Drosophila
Q33600745FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
Q36088216Formation of a Polycomb-Domain in the Absence of Strong Polycomb Response Elements
Q52744369From sequence to function: the impact of the genome sequence on Drosophila biology.
Q41786627Functional genetics in the post-genomics era: building a better roadmap in Drosophila
Q42582850Functional genetics in the post-genomics era: building a better roadmap in Drosophila
Q34390078Functional genomics in Drosophila models of human disease
Q34075046Functional specialization among members of Knickkopf family of proteins in insect cuticle organization.
Q27499410FusionSeq: a modular framework for finding gene fusions by analyzing Paired-End RNA-Sequencing data
Q26749187GATA transcription factors as tissue-specific master regulators for induced responses
Q57987145GDAP2 mutations implicate susceptibility to cellular stress in a new form of cerebellar ataxia
Q27334952GEI-8, a homologue of vertebrate nuclear receptor corepressor NCoR/SMRT, regulates gonad development and neuronal functions in Caenorhabditis elegans
Q30376033Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data
Q34193241Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors
Q33503883Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function
Q30580583Gene set control analysis predicts hematopoietic control mechanisms from genome-wide transcription factor binding data
Q45960693Generalized correlation measure using count statistics for gene expression data with ordered samples.
Q36291409Genetics on the Fly: A Primer on the Drosophila Model System
Q35075548Genome Surveyor 2.0: cis-regulatory analysis in Drosophila
Q35890165Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster
Q91935046Genome-Wide Association Analysis of Anoxia Tolerance in Drosophila melanogaster
Q59297586Genome-Wide Epigenetic Studies in Chicken: A Review
Q37962581Genome-wide DNA methylation in human heart failure.
Q34548248Genome-wide analysis of promoter architecture in Drosophila melanogaster.
Q33635461Genome-wide analysis of regulation of gene expression and H3K9me2 distribution by JIL-1 kinase mediated histone H3S10 phosphorylation in Drosophila
Q35581559Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster
Q35825573Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing
Q36684862Genome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila
Q34477506Genomic Differentiation Between Temperate and Tropical Australian Populations ofDrosophila melanogaster
Q37163051Genomic and Transcriptomic Associations Identify a New Insecticide Resistance Phenotype for the Selective Sweep at the Cyp6g1 Locus of Drosophila melanogaster
Q24626537Genomic screening with RNAi: results and challenges
Q38740865Genomic signatures of local adaptation in the Drosophila immune response
Q35047581Genomics of ecological adaptation in cactophilic Drosophila.
Q50638193Genomics: Hiding in plain sight.
Q30647183Global Mapping of Transcription Factor Binding Sites by Sequencing Chromatin Surrogates: a Perspective on Experimental Design, Data Analysis, and Open Problems
Q35248894Global analysis of transcription factor-binding sites in yeast using ChIP-Seq.
Q36676559H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans
Q100526363H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage
Q36571971HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency.
Q34043275HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans.
Q92203183HOT or not: examining the basis of high-occupancy target regions
Q34481889HP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Q31112464Heat*seq: an interactive web tool for high-throughput sequencing experiment comparison with public data
Q64234636Heme peroxidase HPX-2 protects Caenorhabditis elegans from pathogens
Q39521875Heterochromatin boundaries are hotspots for de novo kinetochore formation
Q90637890Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling
Q48240056High-resolution TADs reveal DNA sequences underlying genome organization in flies.
Q34022627High-resolution mapping studies of chromatin and gene regulatory elements
Q36035868High-resolution profiling of Drosophila replication start sites reveals a DNA shape and chromatin signature of metazoan origins
Q39942911Histone H3 lysine 4 methylation revisited
Q36835735Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription
Q34125015IQSeq: integrated isoform quantification analysis based on next-generation sequencing
Q34055841Identical functional organization of nonpolytene and polytene chromosomes in Drosophila melanogaster
Q37140463Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation
Q29617551Identification of functional elements and regulatory circuits by Drosophila modENCODE
Q34482526Identification of genetic suppressors of the Sin3A knockdown wing phenotype
Q30663573Identification of transcription factor binding sites from ChIP-seq data at high resolution
Q91743420Identifying loci with breeding potential across temperate and tropical adaptation via EigenGWAS and EnvGWAS
Q31032416Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins
Q37594577Implications of chimaeric non-co-linear transcripts
Q34472763In silico pooling of ChIP-seq control experiments
Q35875832In vivo characterization of the Drosophila mRNA 3' end processing core cleavage complex
Q36451325In vivo regulation of E2F1 by Polycomb group genes in Drosophila
Q93089768Inferring Interaction Networks From Multi-Omics Data
Q39162129Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome
Q99721395Insulin and Leptin/Upd2 Exert Opposing Influences on Synapse Number in Fat-Sensing Neurons
Q37585122Insulin/IGF1 signaling inhibits age-dependent axon regeneration
Q33794308Integrated analysis and transcript abundance modelling of H3K4me3 and H3K27me3 in developing secondary xylem.
Q39474443Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes
Q51415958Integrating ChIP-seq with other functional genomics data.
Q60960978Integrating Selection Mapping With Genetic Mapping and Functional Genomics
Q36354909Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes
Q28301622Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
Q34727273Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver
Q30571380InterMine: a flexible data warehouse system for the integration and analysis of heterogeneous biological data
Q92875181Interplay between small RNA pathways shapes chromatin landscapes in C. elegans
Q98461175Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration
Q35502599Introduction to bioinformatics: sequencing technology
Q34055996Intronic L1 retrotransposons and nested genes cause transcriptional interference by inducing intron retention, exonization and cryptic polyadenylation
Q34405062Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation
Q35305993JAK/Stat signaling regulates heart precursor diversification in Drosophila
Q47847250Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
Q35669166LCGbase: A Comprehensive Database for Lineage-Based Co-regulated Genes
Q34802135LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans
Q36143067LMethyR-SVM: Predict Human Enhancers Using Low Methylated Regions based on Weighted Support Vector Machines
Q37461570LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans
Q89916726Lamina-Dependent Stretching and Unconventional Chromosome Compartments in Early C. elegans Embryos
Q41938134Learning the transcriptional regulatory code
Q34149240Lineage programming: navigating through transient regulatory states via binary decisions
Q46304748Lineage-specific chromatin signatures reveal a regulator of lipid metabolism in microalgae
Q28602218Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions
Q34256386Linking the epigenome to the genome: correlation of different features to DNA methylation of CpG islands
Q64064302Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction
Q21184004MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets
Q34974745MITIE: Simultaneous RNA-Seq-based transcript identification and quantification in multiple samples
Q33809896MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data
Q92330174ManiNetCluster: a novel manifold learning approach to reveal the functional links between gene networks
Q46558029Mapping genome-wide transcription-factor binding sites using DAP-seq.
Q41018120Mapping the complexity of transcription control in higher eukaryotes
Q91866548Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans
Q38029323Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.
Q34412274Meiosis: making a break for it
Q52846361Meiotic recombination is suppressed near the histone-defined border of euchromatin and heterochromatin on chromosome 2L of Drosophila melanogaster.
Q89810573Meta-analysis of honey bee neurogenomic response links Deformed wing virus type A to precocious behavioral maturation
Q34182683Methods and strategies for gene structure curation in WormBase
Q34055387MicroRNA expression and regulation in human, chimpanzee, and macaque brains
Q35636600MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells
Q21245309Microarrays, deep sequencing and the true measure of the transcriptome
Q92052901Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
Q34794970Modeling exon expression using histone modifications
Q43984796Molecular biology: A fly in the face of genomics
Q46891558More Drosophila enteroendocrine peptides: Orcokinin B and the CCHamides 1 and 2.
Q21090180Most "dark matter" transcripts are associated with known genes
Q39628462Multidimensional regulation of gene expression in the C. elegans embryo
Q36545027Multiple cis-elements and trans-acting factors regulate dynamic spatio-temporal transcription of let-7 in Caenorhabditis elegans
Q34803562Multiplexed Illumina sequencing libraries from picogram quantities of DNA
Q24611784NCBI Epigenomics: a new public resource for exploring epigenomic data sets
Q34495215NCBI Epigenomics: what's new for 2013.
Q35910335NEAT: a framework for building fully automated NGS pipelines and analyses
Q30779594Navigating and mining modENCODE data
Q37628791Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila
Q38743808Nerve-racking - Apoptotic and non-apoptotic roles of caspases in the nervous system of Drosophila
Q37001113Neurodegeneration in drop-dead mutant drosophila melanogaster is associated with the respiratory system but not with Hypoxia
Q28730711Next-generation genomics: an integrative approach
Q30872605Non-referenced genome assembly from epigenomic short-read data
Q34590386Nuclear hormone receptors in nematodes: evolution and function
Q37029720Nuclear organization and genome function
Q34024543Observing copepods through a genomic lens
Q34140621P-element homing is facilitated by engrailed polycomb-group response elements in Drosophila melanogaster.
Q30370477Parallel functional changes in independent testis-specific duplicates of Aldehyde dehydrogenase in Drosophila
Q35746809Partitioning transcript variation in Drosophila: abundance, isoforms, and alleles
Q36754746Patterning and regulatory associations of DNA methylation are mirrored by histone modifications in insects
Q39334887Patterning of sexually dimorphic neurogenesis in the caenorhabditis elegans ventral cord by Hox and TALE homeodomain transcription factors
Q90567152Patterns and Constraints in the Evolution of Sperm Individualization Genes in Insects, with an Emphasis on Beetles
Q33893293PeakRanger: a cloud-enabled peak caller for ChIP-seq data
Q33887832Phased diploid genome assembly with single-molecule real-time sequencing.
Q37075101Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase
Q34062109Phylogenetic analyses and characterization of RNase X25 from Drosophila melanogaster suggest a conserved housekeeping role and additional functions for RNase T2 enzymes in protostomes
Q51164367Piercing the dark matter: bioinformatics of long-range sequencing and mapping.
Q34548233Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin
Q28534759Pleiohomeotic interacts with the core transcription elongation factor Spt5 to regulate gene expression in Drosophila
Q36245121Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of C. elegans
Q35114443PolyaPeak: detecting transcription factor binding sites from ChIP-seq using peak shape information
Q34472112Polycomb group proteins bind an engrailed PRE in both the "ON" and "OFF" transcriptional states of engrailed
Q42651287Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat.
Q56531068Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells
Q34510126Predicting spatial and temporal gene expression using an integrative model of transcription factor occupancy and chromatin state
Q33777987Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data
Q36093899Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks
Q33691378Preferential Re-Replication of Drosophila Heterochromatin in the Absence of Geminin
Q30957081Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data.
Q34077027Protein composition of interband regions in polytene and cell line chromosomes of Drosophila melanogaster
Q36023310Protein landscape at Drosophila melanogaster telomere-associated sequence repeats.
Q100762049Proteomic analysis of Drosophila CLOCK complexes identifies rhythmic interactions with SAGA and Tip60 complex component NIPPED-A
Q36226039Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling
Q35992049Proximity ligation assays of protein and RNA interactions in the male-specific lethal complex on Drosophila melanogaster polytene chromosomes
Q35198333Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region
Q40115079Quantification of gene-specific methylation of DNMT3B and MTHFR using sequenom EpiTYPER®.
Q42602150Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue.
Q57029686Quantitative proteomics identification of seminal fluid proteins in male
Q36084332REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans.
Q24607002REDfly v3.0: toward a comprehensive database of transcriptional regulatory elements in Drosophila
Q37417866RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2.
Q33924548RNA-seq: technical variability and sampling.
Q46942610RPN-6 determines C. elegans longevity under proteotoxic stress conditions
Q50034263Re-Arrangements in the Cytoplasmic Distribution of Small RNAs Following the Maternal-to-Zygotic Transition in Drosophila Embryos
Q35888902Re-programming of C. elegans male epidermal precursor fates by Wnt, Hox, and LIN-12/Notch activities
Q40374649Recent insights into Groucho co-repressor recruitment and function
Q31003486Reconstruction of composite regulator-target splicing networks from high-throughput transcriptome data
Q26996484Regulated functional alternative splicing in Drosophila
Q35044834Regulation of mechanosensation in C. elegans through ubiquitination of the MEC-4 mechanotransduction channel
Q42429601Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Q37347788Repeated Duplication of Argonaute2 Is Associated with Strong Selection and Testis Specialization in Drosophila.
Q27334718Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes
Q60923509Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model
Q34168361Roles of major facilitator superfamily transporters in phosphate response in Drosophila
Q36180291SAYP and Brahma are important for 'repressive' and 'transient' Pol II pausing
Q34502036SEA: a super-enhancer archive
Q34217607SIN3 is critical for stress resistance and modulates adult lifespan
Q40200523SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans
Q58595457SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA
Q35101944SPIC: a novel similarity metric for comparing transcription factor binding site motifs based on information contents
Q29616757Saccharomyces Genome Database: the genomics resource of budding yeast
Q37856873Selectable genetic markers for nematode transgenesis.
Q57477096Selective interactions between diverse STEs organize the ANT-C Hox cluster
Q38884770Sex combs reduced (Scr) regulatory region of Drosophila revisited
Q36593455Sex-biased networks and nodes of sexually antagonistic conflict in Drosophila
Q47936566Sexual selection shapes development and maturation rates in Drosophila
Q46322055Silencing of Repetitive DNA Is Controlled by a Member of an Unusual Caenorhabditis elegans Gene Family
Q52586071Similarity in replication timing between polytene and diploid cells is associated with the organization of the Drosophila genome.
Q42324193Simultaneous Transcriptional and Epigenomic Profiling from Specific Cell Types within Heterogeneous Tissues In Vivo
Q37534130Simultaneous dimension reduction and adjustment for confounding variation
Q64255703Small Segmental Duplications in Drosophila-High Rate of Emergence and Elimination
Q35945807Snoo and Dpp Act as Spatial and Temporal Regulators Respectively of Adult Progenitor Cells in the Drosophila Trachea
Q34089210Sparse linear modeling of next-generation mRNA sequencing (RNA-Seq) data for isoform discovery and abundance estimation
Q42700397Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors
Q64106584Sperm-Leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm
Q92013123Structural and Functional Dissection of the 5' Region of the Notch Gene in Drosophila melanogaster
Q38185356Synthetic chromatin approaches to probe the writing and erasing of histone modifications
Q33982410Synthetic spike-in standards for RNA-seq experiments
Q37396432Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq
Q34241267Systematic evaluation of factors influencing ChIP-seq fidelity
Q37630764Systems biology from a yeast omics perspective
Q33575083Tau promotes neurodegeneration through global chromatin relaxation
Q52782477Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes.
Q27316318The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals
Q36444189The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub.
Q35034322The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading
Q33645894The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster
Q38815370The FANTOM5 Computation Ecosystem: Genomic Information Hub for Promoters and Active Enhancers.
Q36677056The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster
Q36518592The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation
Q35976728The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster
Q35233511The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcription
Q36088755The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection
Q35780124The MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset
Q64264464The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
Q36664851The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory
Q36359414The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity
Q27499446The case for cloud computing in genome informatics
Q35170671The complex contributions of genetics and nutrition to immunity in Drosophila melanogaster
Q21168558The developmental expression dynamics of Drosophila melanogaster transcription factors
Q29617262The developmental transcriptome of Drosophila melanogaster
Q37718645The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.
Q35803336The epigenome in early vertebrate development.
Q30561877The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage
Q36341429The evolutionary landscape of intergenic trans-splicing events in insects
Q33746582The four aldehyde oxidases of Drosophila melanogaster have different gene expression patterns and enzyme substrate specificities
Q50753040The function of intragenic DNA methylation: insights from insect epigenomes.
Q36642232The genetic architecture of degenerin/epithelial sodium channels in Drosophila
Q30391612The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.
Q35693513The influence of assortativity on the robustness of signal-integration logic in gene regulatory networks
Q37958962The nuclear lamina and heterochromatin: a complex relationship
Q34733633The secretory pathway calcium ATPase PMR-1/SPCA1 has essential roles in cell migration during Caenorhabditis elegans embryonic development
Q34548309The transcriptional diversity of 25 Drosophila cell lines
Q34499471Tissue-specific regulation of chromatin insulator function
Q38690340Trans-splicing enhances translational efficiency in C. elegans.
Q30276192Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation
Q35222700Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster
Q33797842Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level
Q36846342Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster.
Q47129438Transcriptional control of non-apoptotic developmental cell death in C. elegans
Q36343296Transcriptional pausing controls a rapid antiviral innate immune response in Drosophila
Q34228535Transcriptome responses of insect fat body cells to tissue culture environment
Q34032156Transvection is common throughout the Drosophila genome
Q40407654Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration.
Q27309286TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway
Q91917092Two modes of transvection at the eyes absent gene of Drosophila demonstrate plasticity in transcriptional regulatory interactions in cis and in trans
Q39197800Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression.
Q40275213Underrepresentation of active histone modification marks in evolutionarily young genes
Q41958694Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection.
Q30584300Using the Drosophila melanogaster D17-c3 cell culture system to study cell motility
Q26865379Using the ENCODE Resource for Functional Annotation of Genetic Variants
Q36344744VAMP3/Syb and YKT6 are required for the fusion of constitutive secretory carriers with the plasma membrane.
Q90264252Vitellogenins - Yolk Gene Function and Regulation in Caenorhabditis elegans
Q36576333Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila
Q34514538Whole-genome expression analysis in the third instar larval midgut of Drosophila melanogaster
Q37630984Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches.
Q36209122Why is DNA methylation of Igf2 CpG island shore affected during ageing?
Q37197823Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development
Q38243755Wisdom from the fly.
Q46985455WormBase 2017: molting into a new stage.
Q36895137WormBase: Annotating many nematode genomes
Q39493266Wormpath: searching for molecular interaction networks in Caenorhabditis elegans
Q55362576aaquetzalli is required for epithelial cell polarity and neural tissue formation in Drosophila.
Q27311556acal is a long non-coding RNA in JNK signaling in epithelial shape changes during drosophila dorsal closure
Q38908210bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability
Q30572830chroGPS, a global chromatin positioning system for the functional analysis and visualization of the epigenome
Q48299228dUTPase expression correlates with cell division potential in Drosophila melanogaster.
Q37162976flyDIVaS: A Comparative Genomics Resource for Drosophila Divergence and Selection.
Q31082544fussel (fuss)--A negative regulator of BMP signaling in Drosophila melanogaster
Q34044477metaseq: a Python package for integrative genome-wide analysis reveals relationships between chromatin insulators and associated nuclear mRNA.
Q24615914miRBase: integrating microRNA annotation and deep-sequencing data
Q34073658modMine: flexible access to modENCODE data
Q52623895pDHS-ELM: computational predictor for plant DNase I hypersensitive sites based on extreme learning machines.
Q34581018siRNAs from an X-linked satellite repeat promote X-chromosome recognition in Drosophila melanogaster

Search more.