Novel distal eQTL analysis demonstrates effect of population genetic architecture on detecting and interpreting associations

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Novel distal eQTL analysis demonstrates effect of population genetic architecture on detecting and interpreting associations is …
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scholarly articleQ13442814

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P356DOI10.1534/GENETICS.114.167791
P8608Fatcat IDrelease_c25uhj7t5vczbhqsl3m22l5ugi
P932PMC publication ID4224177
P698PubMed publication ID25230953
P5875ResearchGate publication ID265791527

P50authorTerrence S. FureyQ30361580
Sayan MukherjeeQ37392297
P2093author name stringMatthew Weiser
P2860cites workPotential etiologic and functional implications of genome-wide association loci for human diseases and traitsQ22066284
Modeling host genetic regulation of influenza pathogenesis in the collaborative crossQ27336134
Network biology: understanding the cell's functional organizationQ27861027
A nonameric core sequence is required upstream of the LYS genes of Saccharomyces cerevisiae for Lys14p‐mediated activation and apparent repression by lysineQ27937591
Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae. Evidence for a regulatory role of gene LYS14.Q27938356
Harnessing naturally randomized transcription to infer regulatory relationships among genesQ28755546
The large-scale organization of metabolic networksQ29547498
Understanding mechanisms underlying human gene expression variation with RNA sequencingQ29614412
Genetics of gene expression surveyed in maize, mouse and manQ29617297
Genetic dissection of transcriptional regulation in budding yeastQ29618883
Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networksQ31159122
Gene-environment interaction in yeast gene expressionQ33328631
Genetical genomics: spotlight on QTL hotspotsQ33379081
Predicting cellular growth from gene expression signaturesQ33396962
Understanding gene sequence variation in the context of transcription regulation in yeastQ33523271
Cis-acting expression quantitative trait loci in miceQ33771852
High-confidence discovery of genetic network regulators in expression quantitative trait loci dataQ33787812
Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancerQ33791354
The landscape of genetic complexity across 5,700 gene expression traits in yeastQ33818641
Microarray analysis and scale-free gene networks identify candidate regulators in drought-stressed roots of loblolly pine (P. taeda L.).Q33910486
Genome-wide expression quantitative trait loci (eQTL) analysis in maizeQ33947131
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humansQ34092395
Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune diseaseQ34105794
Comparing statistical methods for constructing large scale gene networksQ34137292
Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulationQ34234879
Transcriptome and genome sequencing uncovers functional variation in humansQ34371227
Gene-based testing of interactions in association studies of quantitative traitsQ34611220
Genetic analysis of complex traits in the emerging Collaborative CrossQ35145475
Genetic analysis in the Collaborative Cross breeding population.Q35145484
Bayesian detection of expression quantitative trait loci hot spotsQ35620404
Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in ArabidopsisQ35730032
The Genome Architecture of the Collaborative Cross Mouse Genetic Reference PopulationQ35748258
Matrix eQTL: ultra fast eQTL analysis via large matrix operationsQ35947630
Coanalysis of GWAS with eQTLs reveals disease-tissue associationsQ36082994
Impact of common regulatory single-nucleotide variants on gene expression profiles in whole bloodQ36466430
Modeling causality for pairs of phenotypes in system geneticsQ36643803
Modularity and interactions in the genetics of gene expressionQ37167711
Partial Correlation Estimation by Joint Sparse Regression ModelsQ37405094
Using the emerging Collaborative Cross to probe the immune systemQ37731792
In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14pQ38326443
The YEASTRACT database: an upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiaeQ38494570
Functional and topological characterization of protein interaction networksQ47866212
The Collaborative Cross, a community resource for the genetic analysis of complex traitsQ56896214
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factorsQ73747425
Natural variation in human gene expression assessed in lymphoblastoid cellsQ78885024
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytesQ81305073
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectpopulation geneticsQ31151
P1104number of pages15
P304page(s)879-893
P577publication date2014-09-16
P1433published inGeneticsQ3100575
P1476titleNovel distal eQTL analysis demonstrates effect of population genetic architecture on detecting and interpreting associations
P478volume198

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cites work (P2860)
Q39531221A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population
Q47135336Co-expression networks reveal the tissue-specific regulation of transcription and splicing.
Q64100891Identification of trans-eQTLs using mediation analysis with multiple mediators
Q36248743Informatics resources for the Collaborative Cross and related mouse populations
Q38609350Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression
Q90557541ReQTL: identifying correlations between expressed SNVs and gene expression using RNA-sequencing data
Q39117056Systems Genetics as a Tool to Identify Master Genetic Regulators in Complex Disease
Q92739710Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation

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