Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis

scientific article

Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.3267
P932PMC publication ID4496164
P698PubMed publication ID25940700

P50authorRichard PestellQ7328381
Gabriele Di SanteQ54677042
Adam ErtelQ61162109
Michael P. LisantiQ77913186
Paolo M FortinaQ90314774
Chenguang WangQ98152706
Mathew C CasimiroQ98152746
Sankar AddyaQ114778666
Marco CrosariolQ117233015
Aydin TozerenQ117233037
Elizabeth A SariaQ117250430
P2093author name stringZhiping Li
Erik S Knudsen
Andrew Arnold
Zuoren Yu
William Dampier
Robert D Cardiff
Emanuele Loro
Alexandros Papanikolaou
P2860cites workCyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial functionQ24554383
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1Q24595709
Cyclin D1 in breast cancer pathogenesisQ27824841
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitmentQ28235209
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismQ28256059
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4Q28266936
A novel cyclin encoded by a bcl1-linked candidate oncogeneQ28268235
The UCSC genome browser and associated toolsQ28273417
Using galaxy to perform large-scale interactive data analysesQ28277397
Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogeneQ72061272
G1-S transition defects occur in most breast cancers and predict outcomeQ73207809
Cyclin D1 and retinoblastoma gene expression in human breast carcinoma: correlation with tumour proliferation and oestrogen receptor statusQ73634270
Minireview: Cyclin D1: normal and abnormal functionsQ28279069
Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesisQ28291864
Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin miceQ28510765
Requirement for CDK4 kinase function in breast cancerQ28585905
Stat3 as an oncogeneQ29614606
Functional interactions of the retinoblastoma protein with mammalian D-type cyclinsQ29618856
JASPAR 2010: the greatly expanded open-access database of transcription factor binding profilesQ29619342
Extracting transcription factor targets from ChIP-Seq dataQ33474249
Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesisQ33639152
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiationQ33715499
pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-Q33854336
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathwayQ33872322
Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosisQ33880827
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathwayQ33884776
microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signalingQ33929324
ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in miceQ34252194
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regionsQ34295503
Chromosome segregation and genomic stabilityQ34326891
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic miceQ34342812
Cell fate determination factor Dachshund reprograms breast cancer stem cell functionQ34503221
Function of a human cyclin gene as an oncogeneQ34994859
Cyclin D1 determines mitochondrial function in vivoQ35070938
A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancersQ35099578
Cyclin D1 governs adhesion and motility of macrophagesQ35153599
Living with or without cyclins and cyclin-dependent kinasesQ35951291
Mechanisms leading to chromosomal instability.Q35990964
Immunodetectable cyclin D(1)is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesionsQ36622922
Mechanisms of chromosomal instability.Q37193068
Causes and consequences of aneuploidy in cancer.Q37978107
Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present.Q38175443
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.Q38347118
Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migrationQ40027619
Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation.Q40463285
An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogeneQ40617469
Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signalingQ41493003
Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformationQ42801826
Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breastQ47854842
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.Q51584233
Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.Q51805313
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)8525-8538
P577publication date2015-04-01
P1433published inOncotargetQ1573155
P1476titleKinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
P478volume6

Reverse relations

cites work (P2860)
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Q33598936Astrocyte elevated gene-1 promotes the proliferation and invasion of breast cancer cells by activating the Wnt/β-catenin signaling pathway
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Q34556943Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.
Q91341626Cyclin D1 integrates G9a-mediated histone methylation
Q89498262Cyclin D1 overexpression induces global transcriptional downregulation in lymphoid neoplasms
Q52714385Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome.
Q99555085Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
Q96817958Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1
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Q60017682Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies
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Q89883746MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1
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Q30252204The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer

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