Potent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins

scholarly article

Potent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2006PNAS..103.1876D
P356DOI10.1073/PNAS.0509451103
P932PMC publication ID1413648
P698PubMed publication ID16446436
P5875ResearchGate publication ID7328346

P50authorStephanie SchüllerQ47097350
Paul DeanQ57269178
P2093author name stringMarc Maresca
Alan D Phillips
Brendan Kenny
P2860cites workDiarrheagenic Escherichia coliQ24533466
Role of intimin and bundle-forming pili in enteropathogenic Escherichia coli adhesion to pediatric intestinal tissue in vitroQ33752405
Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspGQ33768868
The gut at war: the consequences of enteropathogenic Escherichia coli infection as a factor of diarrhea and malnutritionQ33843603
SepZ/EspZ is secreted and translocated into HeLa cells by the enteropathogenic Escherichia coli type III secretion systemQ33883322
Role of the eaeA gene in experimental enteropathogenic Escherichia coli infectionQ33902441
Role of tir and intimin in the virulence of rabbit enteropathogenic Escherichia coli serotype O103:H2.Q34003963
Management of infectious diarrhoeaQ35598312
Enteropathogenic Escherichia coli: unravelling pathogenesisQ36010824
EPEC's weapons of mass subversionQ36032356
Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coliQ39512479
Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract.Q39830323
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.Q39996509
Differential regulation of Na+/H+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cellsQ40568292
Interaction of enteropathogenic Escherichia coli with human intestinal mucosa: role of effector proteins in brush border remodeling and formation of attaching and effacing lesionsQ40997195
A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 modelQ41138277
Kinetic separation and characterization of three sugar transport modes in Caco-2 cellsQ41200175
Characterization of an electrogenic sodium/glucose cotransporter in a human colon epithelial cell lineQ41352353
Enteropathogenic Escherichia coli type III effectors EspG and EspG2 disrupt the microtubule network of intestinal epithelial cellsQ41862570
Effects of enteropathogenic Escherichia coli on microvillar membrane proteins during organ culture of rabbit intestinal mucosaQ41874908
Organ culture of rabbit ileum as a model for the investigation of the mechanism of intestinal damage by enteropathogenic Escherichia coliQ43199098
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in miceQ44375935
More than apical: Distribution of SGLT1 in Caco-2 cellsQ44457706
Enteropathogenic Escherichia coli (EPEC)-- a crafty subversive little bug.Q44980808
Targeting of enteropathogenic Escherichia coli EspF to host mitochondria is essential for bacterial pathogenesis: critical role of the 16th leucine residue in EspF.Q45144471
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cellsQ48042079
Enteropathogenic and enterohaemorrhagic Escherichia coli deliver a novel effector called Cif, which blocks cell cycle G2/M transitionQ48217964
The human Na+-glucose cotransporter is a molecular water pumpQ48939861
Co-ordinate regulation of distinct host cell signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules.Q52546261
Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein.Q52560716
Enteropathogenic Escherichia coli EspG disrupts microtubules and in conjunction with Orf3 enhances perturbation of the tight junction barrier.Q53861786
Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells.Q54517340
A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.Q54574143
Emergence of a 'hyperinfectious' bacterial state after passage of Citrobacter rodentium through the host gastrointestinal tractQ56967958
The EspB protein of enterohaemorrhagic Escherichia coli interacts directly with alpha-cateninQ77936911
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
enteropathogenQ63500873
P304page(s)1876-1881
P577publication date2006-01-30
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePotent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins
P478volume103

Reverse relations

cites work (P2860)
Q37690960A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis
Q46479145Actin cytoskeleton manipulation by effector proteins secreted by diarrheagenic Escherichia coli pathotypes
Q43621625Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens
Q35191956Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation.
Q24293521Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function
Q33528372Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors
Q38325835Cell-surface nucleolin is sequestered into EPEC microcolonies and may play a role during infection
Q30010247Comparative analysis of EspF variants in inhibition of Escherichia coli phagocytosis by macrophages and inhibition of E. coli translocation through human- and bovine-derived M cells.
Q38816242Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment
Q33326978Deciphering interplay between Salmonella invasion effectors
Q33775617Direct injection of functional single-domain antibodies from E. coli into human cells
Q33358967Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines
Q39413863Do Caco-2 subclones provide more appropriate in vitro models for understanding how human enteric pathogens cause disease?
Q42230943Dynamics of brush border remodeling induced by enteropathogenic E. coli
Q38724200EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity
Q24596978Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea
Q35888490Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions.
Q38926009Enterohemorrhagic Escherichia coli colonization of human colonic epithelium in vitro and ex vivo
Q52688929Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation.
Q41506828Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules, contribute to tight junction perturbation and inhibit restoration
Q38021502Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms
Q26996996Enteropathogenic E. coli: breaking the intestinal tight junction barrier
Q40153854Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function.
Q37055770Enteropathogenic Escherichia coli infection inhibits intestinal serotonin transporter function and expression.
Q37391808Enteropathogenic Escherichia coli inhibits intestinal vitamin B1 (thiamin) uptake: studies with human-derived intestinal epithelial Caco-2 cells
Q41433037Enteropathogenic Escherichia coli, Samonella, Shigella and Yersinia: cellular aspects of host-bacteria interactions in enteric diseases
Q35784058Enteropathogenic Escherichia coli-induced epidermal growth factor receptor activation contributes to physiological alterations in intestinal epithelial cells
Q38452303Enteropathogenic Escherichia coli-induced macrophage inhibitory cytokine 1 mediates cancer cell survival: an in vitro implication of infection-linked tumor dissemination
Q34177961Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
Q26830066Enteropathogenic escherichia coli infection in children
Q39418879Escherichia coli-induced epithelial hyporesponsiveness to secretagogues is associated with altered CFTR localization
Q34889643Expression of enteropathogenic Escherichia coli map is significantly different than that of other type III secreted effectors in vivo
Q27025808From Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormones
Q38101247From the gut to the brain: journey and pathophysiological effects of the food-associated trichothecene mycotoxin deoxynivalenol
Q38830802Generation of a MDCK cell line with constitutive expression of the Enteropathogenic E. coli effector protein Map as an in vitro model of pathogenesis.
Q35122829In vitro exposure to Escherichia coli decreases ion conductance in the jejunal epithelium of broiler chickens
Q41368628Increased intracellular calcium level and impaired nutrient absorption are important pathogenicity traits in the chicken intestinal epithelium during Campylobacter jejuni colonization.
Q38007348Infection strategies of enteric pathogenic Escherichia coli
Q37843682Infectious diarrhea: Cellular and molecular mechanisms
Q64083367Influence of the intestinal microbiota on disease susceptibility in kittens with experimentally-induced carriage of atypical enteropathogenic Escherichia coli
Q34576318Insights into the pathogenesis of enteropathogenic E. coli using an improved intestinal enterocyte model
Q27012975Interspecies communication in the gut, from bacterial delivery to host-cell response
Q37780578LEEways: tales of EPEC, ATEC and EHEC.
Q37055281Mimicking small G-proteins: an emerging theme from the bacterial virulence arsenal
Q43717369Molecular mechanisms of Escherichia coli pathogenicity
Q33582232Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa
Q38912737Pathogen-induced secretory diarrhea and its prevention
Q37264192Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines
Q38084050Probiotics in Clostridium difficile infection: reviewing the need for a multistrain probiotic
Q36911360Prolonged NF-κB activation by a macrophage inhibitory cytokine 1-linked signal in enteropathogenic Escherichia coli-infected epithelial cells
Q34375210Recent advances in understanding enteric pathogenic Escherichia coli.
Q30432222Remodeling of the intestinal brush border underlies adhesion and virulence of an enteric pathogen
Q37816402Sticky situation: localized adherence of enteropathogenic Escherichia coli to the small intestine epithelium
Q24310471The EHEC-host interactome reveals novel targets for the translocated intimin receptor
Q37777278The EspF effector, a bacterial pathogen's Swiss army knife
Q34571628The N-terminal domain of EspF induces host cell apoptosis after infection with enterohaemorrhagic Escherichia coli O157:H7.
Q55433458The Role of Ion Transporters in the Pathophysiology of Infectious Diarrhea.
Q41971348The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector
Q38255302The cell death response to enteropathogenic Escherichia coli infection
Q34921824The effector repertoire of enteropathogenic E. coli: ganging up on the host cell
Q28478223The enteropathogenic E. coli (EPEC) Tir effector inhibits NF-κB activity by targeting TNFα receptor-associated factors
Q28474712The enteropathogenic E. coli effector EspF targets and disrupts the nucleolus by a process regulated by mitochondrial dysfunction
Q41870508The enteropathogenic Escherichia coli effector protein EspF decreases sodium hydrogen exchanger 3 activity
Q37557346The role of epithelial malfunction in the pathogenesis of enteropathogenic E. coli-induced diarrhea
Q30480560The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.
Q40171429Translocation of enteropathogenic Escherichia coli across an in vitro M cell model is regulated by its type III secretion system.
Q36193949Transmissible Gastroenteritis Virus Infection Enhances SGLT1 and GLUT2 Expression to Increase Glucose Uptake
Q38735104Tricellular Tight Junction Protein Tricellulin Is Targeted by the Enteropathogenic Escherichia coli Effector EspG1, Leading to Epithelial Barrier Disruption.

Search more.