Infectious diarrhea: Cellular and molecular mechanisms

scientific article published on January 2010

Infectious diarrhea: Cellular and molecular mechanisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/GMIC.1.1.11036
P932PMC publication ID3035144
P698PubMed publication ID21327112
P5875ResearchGate publication ID49841736

P2093author name stringKim Hodges
Ravinder Gill
P2860cites workDevelopment of functional gastrointestinal disorders after Giardia lamblia infectionQ21261866
Diarrheagenic Escherichia coliQ24533466
Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayersQ24561503
Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbitQ24607564
Rotaviruses: from pathogenesis to vaccinationQ24609374
Toxin B is essential for virulence of Clostridium difficileQ24647539
Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitroQ24651060
Cytokine response by human monocytes to Clostridium difficile toxin A and toxin BQ24652880
Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical PathwayQ27485323
The Three-dimensional Crystal Structure of Cholera ToxinQ27729852
Filamentous phages linked to virulence of Vibrio choleraeQ28180172
SLC26A3 mutations in congenital chloride diarrheaQ28215471
Entamoeba histolytica Causes Intestinal Secretion: Role of SerotoninQ28265508
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extensionQ28571742
STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase GQ28584109
Clostridium difficile infection: new developments in epidemiology and pathogenesisQ29615330
Pathogenic Escherichia coliQ29616738
Inhibition of the complement membrane attack complex by the galactose-specific adhesion of Entamoeba histolyticaQ30311439
Identification and characterization of a cyclooxygenase-like enzyme from Entamoeba histolyticaQ30449610
Rotavirus enterotoxin NSP4 binds to the extracellular matrix proteins laminin-beta3 and fibronectinQ30835929
Cytoplasmic calcium measurement in rotavirus enterotoxin-enhanced green fluorescent protein (NSP4-EGFP) expressing cells loaded with Fura-2.Q30938272
Strain-dependent induction of enterocyte apoptosis by Giardia lamblia disrupts epithelial barrier function in a caspase-3-dependent mannerQ31078416
Vibrio cholerae-induced cellular responses of polarized T84 intestinal epithelial cells are dependent on production of cholera toxin and the RTX toxinQ31082589
Rotavirus Infection Reduces Sucrase-Isomaltase Expression in Human Intestinal Epithelial Cells by Perturbing Protein Targeting and Organization of Microvillar CytoskeletonQ32041827
Contagious acute gastrointestinal infectionsQ33209507
Neurotensin is a proinflammatory neuropeptide in colonic inflammationQ33844018
Cysteine proteinases and the pathogenesis of amebiasisQ33886180
Role of the eaeA gene in experimental enteropathogenic Escherichia coli infectionQ33902441
Racecadotril in the treatment of acute watery diarrhea in childrenQ33914027
Cytotoxic effects of the Clostridium difficile toxinsQ33917350
The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation.Q34004127
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
Lysogenic conversion by a filamentous phage encoding cholera toxinQ34062735
Infection of Cultured Mouse Macrophages with Shigella flexneri.Q34155768
Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxinsQ34157039
Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VII. Enteropathogenic Escherichia coli: physiological alterations from an extracellular positionQ34283876
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDELQ34289590
Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VIII. Pathological consequences of rotavirus infection and its enterotoxinQ34304499
Potent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteinsQ34478656
Rotavirus proteins: structure and assemblyQ34557876
slc26a3 (dra)-deficient mice display chloride-losing diarrhea, enhanced colonic proliferation, and distinct up-regulation of ion transporters in the colonQ34568862
How do the rotavirus NSP4 and bacterial enterotoxins lead differently to diarrhea?Q34577989
Structure and function of the heat-stable enterotoxin receptor/guanylyl cyclase C.Q34599942
New trends in Clostridium difficile virulence and pathogenesisQ34605658
The epithelial brush border Na+/H+ exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain-containing Na+/H+ exchanger regulatory factor (NHERF) proteinsQ34772918
Transcriptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenicityQ34993857
Rapid modulation of electrolyte transport in Caco-2 cell monolayers by enteropathogenic Escherichia coli (EPEC) infectionQ35349325
Phosphorylation of myosin light chain at distinct sites and its association with the cytoskeleton during enteropathogenic Escherichia coli infectionQ35501685
Mechanism underlying inhibition of intestinal apical Cl/OH exchange following infection with enteropathogenic E. coliQ35589274
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. choleraeQ35629352
Calicivirus 3C-like proteinase inhibits cellular translation by cleavage of poly(A)-binding protein.Q35705814
Structural and functional changes of the duodenum in human norovirus infectionQ42445601
Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenumQ42500499
Sodium and chloride absorptive defects in the small intestine in Slc26a6 null miceQ42518172
The mode of action of Shiga toxin on peptide elongation of eukaryotic protein synthesisQ42856082
Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogensQ43621625
Loss of the NHE2 Na+/H+exchanger has no apparent effect on diarrheal state of NHE3-deficient miceQ43797517
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channelQ43911618
Role of prostaglandins and calcium in the effects of Entamoeba histolytica on colonic electrolyte transportQ43942749
The mode of action of Vibrio cholerae cytolysin. The influences on both erythrocytes and planar lipid bilayersQ44069726
Disaccharidase activities in small intestine of rotavirus-infected suckling mice: a histochemical studyQ44348915
Giardia lamblia infections become clinically evident by eliciting symptoms of irritable bowel syndromeQ44536322
PKC zeta participates in activation of inflammatory response induced by enteropathogenic E. coliQ44538196
Molecular cloning, expression and characterization of a serine proteinase inhibitor gene from Entamoeba histolyticaQ44708372
Proteinase inhibitors TPCK and TLCK prevent Entamoeba histolytica induced disturbance of tight junctions and microvilli in enteric cell layers in vitro.Q44906113
Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathwayQ45129874
Health Care Costs and Mortality Associated with Nosocomial Diarrhea Due to Clostridium difficileQ45164970
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.Q45986472
Longitudinal study of rotavirus infection and gastroenteritis in families served by a pediatric medical practice: clinical and epidemiologic observations.Q45996761
Heat-stable enterotoxin of Escherichia coli (STa) can stimulate duodenal HCO3(-) secretion via a novel GC-C- and CFTR-independent pathwayQ46138775
Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancerQ46334426
Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 levelQ46693523
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchangerQ47852356
Substance P receptor expression in intestinal epithelium inClostridium difficiletoxin A enteritis in ratsQ47876264
Entamoeba histolytica disturbs the tight junction complex in human enteric T84 cell layers.Q49076297
Type III secretion effectors of the IpaH family are E3 ubiquitin ligasesQ50066742
Culture supernatant of Shiga toxin-producing Escherichia coli strains provoke fluid accumulation in rabbit ileal loopsQ50231945
Shigella flexneri regulates tight junction-associated proteins in human intestinal epithelial cellsQ51191281
Human zonulin, a potential modulator of intestinal tight junctions.Q52162731
NSP4 elicits age-dependent diarrhea and Ca(2+)mediated I(-) influx into intestinal crypts of CF mice.Q52536014
Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cellsQ52541093
Age-dependent diarrhea induced by a rotaviral nonstructural glycoproteinQ52547346
Galectin-3 modulates T cell activity and is reduced in the inflamed intestinal epithelium in IBD.Q53615171
Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo.Q53845870
Enteropathogenic Escherichia coli EspG disrupts microtubules and in conjunction with Orf3 enhances perturbation of the tight junction barrierQ53861786
C. difficile toxin A increases intestinal permeability and induces Cl- secretion.Q54319043
Roles of globotriosyl- and galabiosylceramide in verotoxin binding and high affinity interferon receptor.Q54395553
Muramylpeptide shedding modulates cell sensing of Shigella flexneri.Q54430471
The Shiga toxin 2 B subunit inhibits net fluid absorption in human colon and elicits fluid accumulation in rat colon loops.Q54502689
Small intestinal injury in a neonatal rat model of giardiasis is strain dependentQ58811073
Shiga toxin binding in normal and inflamed human intestinal mucosaQ59307361
Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actin-specific ADP-ribosyltransferase)-producing strainsQ61708585
Electron microscope studies of experimental Entamoeba histolytica infection in the guinea pig. II. Early cellular and vascular changes accompanying invasion of the lamina propriaQ67519110
Study on the mechanism of Giardia lamblia induced diarrhoea in miceQ68064286
Pathophysiology of small intestinal malabsorption in gerbils infected with Giardia lambliaQ68213703
Changes in cyclic 3'5'-adenosine monophosphate tissue concentration and net fluid transport in the cat's small intestine elicited by cholera toxin, arachidonic acid, vasoactive intestinal polypeptide and 5-hydroxytryptamineQ70172927
Expression of Vibrio cholerae zonula occludens toxin and analysis of its subcellular localizationQ73251552
Bacterial protein toxins--general conclusionsQ73285707
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammationQ73867640
CGRP upregulation in dorsal root ganglia and ileal mucosa during Clostridium difficile toxin A-induced enteritisQ74153825
Rotavirus infection impairs intestinal brush-border membrane Na(+)-solute cotransport activities in young rabbitsQ74228020
Rotavirus and calicivirus infections of the gastrointestinal tractQ79216701
Differential regulation of cholera toxin-inhibited Na-H exchange isoforms by butyrate in rat ileumQ80775988
[Physiopathology of Rotavirus diarrhea]Q81502312
Recent insights into the mucosal reactions associated with Giardia lamblia infectionsQ36267036
Astrovirus increases epithelial barrier permeability independently of viral replicationQ36314957
Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.Q36422508
Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: co-opting basic mechanisms of endoplasmic reticulum-associated degradationQ36435579
Astrovirus induces diarrhea in the absence of inflammation and cell deathQ36538876
Characterization of the enzymatic activity of the actin cross-linking domain from the Vibrio cholerae MARTX Vc toxinQ36627241
Caspases mediate processing of the capsid precursor and cell release of human astrovirusesQ36684035
Mechanisms of epithelial dysfunction in giardiasisQ36752503
Diarrhea as a cause of mortality in a mouse model of infectious colitisQ36955014
Enteropathogenic Escherichia coli infection inhibits intestinal serotonin transporter function and expression.Q37055770
Enterocyte chloride and water secretion into the small intestine after enterotoxin challenge: unifying hypothesis or intellectual dead end?Q37229379
Decreased expression of colonic Slc26a3 and carbonic anhydrase iv as a cause of fatal infectious diarrhea in miceQ37333481
Differential activation of human TLR4 by Escherichia coli and Shigella flexneri 2a lipopolysaccharide: combined effects of lipid A acylation state and TLR4 polymorphisms on signalingQ37337410
Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretionQ37379322
Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritisQ37380450
Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP.Q38362715
Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis.Q39510203
Amebic infection in the human colon induces cyclooxygenase-2.Q39520065
Release of Toll-like receptor-2-activating bacterial lipoproteins in Shigella flexneri culture supernatantsQ39522417
Pseudomembranous enterocolitis (antibiotic-related colitis)Q39618509
gp96 is a human colonocyte plasma membrane binding protein for Clostridium difficile toxin A.Q39757721
Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3.Q39801146
The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenic Escherichia coli.Q39807355
Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196.Q39829481
Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract.Q39830323
Suppression of astrovirus replication by an ERK1/2 inhibitorQ39977595
Norwalk virus nonstructural protein p48 forms a complex with the SNARE regulator VAP-A and prevents cell surface expression of vesicular stomatitis virus G proteinQ40011733
Toll-like receptor 9-dependent macrophage activation by Entamoeba histolytica DNA.Q40055987
Unipolar reorganization of F-actin layer at bacterial division and bundling of actin filaments by plastin correlate with movement of Shigella flexneri within HeLa cellsQ40148193
The phosphothreonine lyase activity of a bacterial type III effector familyQ40170436
Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein cofilinQ40182269
Balance of bacterial pro- and anti-inflammatory mediators dictates net effect of enteropathogenic Escherichia coli on intestinal epithelial cellsQ40345219
The innate immune response to Entamoeba histolytica lipopeptidophosphoglycan is mediated by toll-like receptors 2 and 4.Q40418682
Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosisQ40426449
Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKC alpha in human intestinal epithelial cellsQ40436309
Differential regulation of Na+/H+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cellsQ40568292
Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic featuresQ40653214
Distinct effects of Vibrio cholerae haemagglutinin/protease on the structure and localization of the tight junction-associated proteins occludin and ZO-1.Q40826540
Neil A. Dayton 1893-1977. A personal tributeQ40834947
Vibrio cholerae ACE stimulates Ca(2+)-dependent Cl(-)/HCO(3)(-) secretion in T84 cells in vitroQ40861457
Enteropathogenic E. coli attenuates secretagogue-induced net intestinal ion transport but not Cl- secretionQ40968480
Interaction of heat-stable enterotoxins with human colonic (T84) cells: modulation of the activation of guanylyl cyclaseQ41506609
Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosisQ41738688
The enteropathogenic Escherichia coli effector protein EspF decreases sodium hydrogen exchanger 3 activityQ41870508
Pathology of astrovirus associated diarrhoea in a paediatric bone marrow transplant recipientQ41909126
Suppression of NF-kappa B activation and proinflammatory cytokine expression by Shiga toxin-producing Escherichia coliQ42436813
P433issue1
P921main subjectdiarrheaQ40878
P304page(s)4-21
P577publication date2010-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inGut microbesQ26841922
P1476titleInfectious diarrhea: Cellular and molecular mechanisms
P478volume1

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