| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1009873859 |
| P356 | DOI | 10.1038/SJ.ONC.1209004 |
| P932 | PMC publication ID | 1413679 |
| P698 | PubMed publication ID | 16278684 |
| P5875 | ResearchGate publication ID | 7488943 |
| P50 | author | B Mark Evers | Q89810329 |
| P2093 | author name string | X Wang | |
| Y Zhou | |||
| Q Wang | |||
| P2860 | cites work | Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 |
| Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin | Q24522854 | ||
| Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage | Q24534352 | ||
| Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway | Q24537174 | ||
| GSK-3: tricks of the trade for a multi-tasking kinase | Q24624069 | ||
| Phosphorylation and regulation of Raf by Akt (protein kinase B) | Q28138863 | ||
| Interleukin-8 as an autocrine growth factor for human colon carcinoma cells in vitro | Q28141962 | ||
| Beta-catenin--a linchpin in colorectal carcinogenesis? | Q28198211 | ||
| Synthesis and function of 3-phosphorylated inositol lipids | Q28200755 | ||
| Regulation of cell apoptosis by protein kinase c delta | Q28201453 | ||
| Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation | Q28205114 | ||
| Glycogen synthase kinase-3: properties, functions, and regulation | Q28212200 | ||
| Glycogen synthase kinase-3: functions in oncogenesis and development | Q28212979 | ||
| Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization | Q28290083 | ||
| The MAPK signaling cascade | Q28292599 | ||
| The glamour and gloom of glycogen synthase kinase-3 | Q29620533 | ||
| Mitogen-activated protein kinases: specific messages from ubiquitous messengers | Q30303652 | ||
| Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation | Q30452661 | ||
| Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription | Q31462537 | ||
| Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells | Q33652139 | ||
| The role of COX-2 in intestinal cancer | Q33834299 | ||
| Role of cytokines in the pathogenesis of inflammatory bowel disease | Q33896046 | ||
| Control of the eukaryotic cell cycle by MAP kinase signaling pathways. | Q34071364 | ||
| Gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways | Q34139335 | ||
| Molecular targets of lithium action | Q34192797 | ||
| GSK3 takes centre stage more than 20 years after its discovery | Q34374129 | ||
| Cyclooxygenase-2 Biology | Q35551907 | ||
| Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt | Q35918889 | ||
| Beta-catenin mutations in cell lines established from human colorectal cancers | Q36586200 | ||
| Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB | Q38349616 | ||
| Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-kappaB-independent pathway | Q38353173 | ||
| Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells | Q40527726 | ||
| Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1. | Q40555578 | ||
| Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages | Q40581037 | ||
| Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). | Q40671035 | ||
| Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes | Q40778287 | ||
| Roles of Akt and glycogen synthase kinase 3beta in the ultraviolet B induction of cyclooxygenase-2 transcription in human keratinocytes. | Q40801705 | ||
| Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. | Q40915594 | ||
| PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells | Q40972626 | ||
| Regulation and function of the JNK subgroup of MAP kinases | Q41659032 | ||
| An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. | Q41810461 | ||
| Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappaB signal pathways. | Q42500751 | ||
| Protein kinase Cdelta overexpression enhances radiation sensitivity via extracellular regulated protein kinase 1/2 activation, abolishing the radiation-induced G(2)-M arrest. | Q42813840 | ||
| Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation | Q43582803 | ||
| Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation | Q43847013 | ||
| Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications | Q44098361 | ||
| Differential Role of Protein Kinase Cδ Isoform in Agonist-induced Dense Granule Secretion in Human Platelets | Q44631925 | ||
| Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts | Q44799548 | ||
| Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets | Q44970399 | ||
| Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth | Q45054541 | ||
| Transcriptional activation of interleukin-8 by beta-catenin-Tcf4. | Q52115561 | ||
| Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation. | Q53233594 | ||
| Augmentation of therapeutic angiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3beta activity. | Q53635273 | ||
| Protein Kinase C Regulates Integrin-induced Activation of the Extracellular Regulated Kinase Pathway Upstream of Shc | Q58323655 | ||
| Hypertonic Stress Activates Glycogen Synthase Kinase 3β-mediated Apoptosis of Renal Medullary Interstitial Cells, Suppressing an NFκB-driven Cyclooxygenase-2-dependent Survival Pathway | Q64377327 | ||
| The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells | Q72134277 | ||
| Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways | Q73679077 | ||
| Downregulation of mitogen-activated protein kinases in human colon cancers | Q73686413 | ||
| Alterations of MAPK activities associated with intestinal cell differentiation | Q73980212 | ||
| Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor | Q80337321 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 43-50 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase | |
| P478 | volume | 25 |
| Q38324927 | 2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation |
| Q42734250 | A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells |
| Q44741917 | A role for glycogen synthase kinase-3 in antagonizing mycobacterial immune evasion by negatively regulating IL-10 induction |
| Q33714703 | Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis |
| Q35763147 | Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity |
| Q35994722 | Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. |
| Q28564696 | An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth |
| Q54977964 | Antagonistic role of GSK3 isoforms in glioma survival. |
| Q36792589 | Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes. |
| Q34438059 | Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback |
| Q49798082 | Cigarette Smoke Extract Enhances IL-17AInduced IL-8 Production via Up-Regulation of IL-17R in Human Bronchial Epithelial Cells |
| Q37174611 | Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload |
| Q27322328 | Control of Hes7 expression by Tbx6, the Wnt pathway and the chemical Gsk3 inhibitor LiCl in the mouse segmentation clock |
| Q46901584 | Correlations of mRNA expression and in vitro chemosensitivity to enzastaurin in freshly explanted human tumor cells |
| Q92099145 | Cyclooxygenase-2 in Endometriosis |
| Q33712312 | Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol |
| Q44518261 | Effects of fluoxetine on CRF and CRF1 expression in rats exposed to the learned helplessness paradigm |
| Q37021902 | Enhancement of paclitaxel-induced breast cancer cell death via the glycogen synthase kinase-3β-mediated B-cell lymphoma 2 regulation |
| Q40095580 | Epidermal growth factor inhibits glycogen synthase kinase-3 (GSK-3) and beta-catenin transcription in cultured ARPE-19 cells |
| Q39193149 | Forecasting cell death dose-response from early signal transduction responses in vitro |
| Q34449946 | Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition |
| Q36508885 | GSK3beta is a negative regulator of platelet function and thrombosis |
| Q98292629 | Gamma radiation improves AD pathogenesis in APP/PS1 mouse model by potentiating insulin sensitivity |
| Q31154756 | Gene set enrichment in eQTL data identifies novel annotations and pathway regulators |
| Q34528331 | Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress |
| Q24597129 | Glycogen synthase kinase 3: a point of convergence for the host inflammatory response |
| Q80003785 | Glycogen synthase kinase 3beta and beta-catenin are involved in the injury and repair of bronchial epithelial cells induced by scratching |
| Q33886299 | Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension. |
| Q36929443 | Glycogen synthase kinase-3 (GSK-3) regulates TGF-β₁-induced differentiation of pulmonary fibroblasts. |
| Q24655658 | Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation |
| Q100381935 | Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction |
| Q80665120 | Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis |
| Q35834731 | Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury. |
| Q42493350 | Insulin-like growth factor as a novel stimulator for somatolactin secretion and synthesis in carp pituitary cells via activation of MAPK cascades. |
| Q33284874 | Integration of signal pathways for stretch-dependent growth and differentiation in vascular smooth muscle |
| Q39260362 | Interaction between ERK and GSK3beta mediates basic fibroblast growth factor-induced apoptosis in SK-N-MC neuroblastoma cells |
| Q38583791 | Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3β pathways in vivo. |
| Q36002945 | Mechanism of β-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 β-inactivated prostate cancer cells |
| Q36985073 | NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation. |
| Q28478149 | NFATc1 regulation of TRAIL expression in human intestinal cells |
| Q34542040 | Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation |
| Q28387039 | Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells |
| Q34166917 | Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway |
| Q37438495 | Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish |
| Q54389473 | PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses. |
| Q57793312 | PTPN11 plays oncogenic roles and is a therapeutic target for BRAF wild-type melanomas |
| Q35922200 | Protein kinase C δ (PKCδ)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia |
| Q39915494 | Protein kinase Cdelta negatively regulates hedgehog signaling by inhibition of Gli1 activity |
| Q28537891 | Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks |
| Q36738312 | Regulation of MAPKs by growth factors and receptor tyrosine kinases |
| Q37113710 | Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition |
| Q36170828 | Remote Liver Ischemic Preconditioning Protects against Sudden Cardiac Death via an ERK/GSK-3β-Dependent Mechanism |
| Q30438487 | Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors |
| Q44785466 | Signal transduction mechanisms for autocrine/paracrine regulation of somatolactin-α secretion and synthesis in carp pituitary cells by somatolactin-α and -β. |
| Q33634084 | Sphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytes |
| Q34100964 | Suppression of Neurotensin Receptor Type 1 Expression and Function by Histone Deacetylase Inhibitors in Human Colorectal Cancers |
| Q36347242 | TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium. |
| Q34828662 | The PTEN-PI3K pathway: of feedbacks and cross-talks |
| Q91962615 | The Upstream Pathway of mTOR-Mediated Autophagy in Liver Diseases |
| Q81306401 | The glycogen synthase kinase (GSK) 3beta represses RNA polymerase I transcription |
| Q23911302 | The role of glycogen synthase kinase 3 beta in the transformation of epidermal cells |
| Q93173303 | The roles of mechanosensitive ion channels and associated downstream MAPK signaling pathways in PDLC mechanotransduction |
| Q36959923 | Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action |
| Q33771582 | Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2. |
| Q38617940 | Unconventional MAPK-GSK-3β Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma |
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