| scholarly article | Q13442814 |
| P356 | DOI | 10.1128/JVI.00738-06 |
| P8608 | Fatcat ID | release_beb4wp5ycfdzddpaayxjzzz5ai |
| P932 | PMC publication ID | 1617239 |
| P698 | PubMed publication ID | 16973573 |
| P50 | author | Eckard Wimmer | Q106692 |
| P2093 | author name string | Steffen Mueller | |
| Dimitris Papamichail | |||
| J Robert Coleman | |||
| Steven Skiena | |||
| P2860 | cites work | The RNA encompassing the internal ribosome entry site in the poliovirus 5' nontranslated region enhances the encapsidation of genomic RNA | Q74070829 |
| Poliovirus cell entry: common structural themes in viral cell entry pathways | Q24550839 | ||
| Transgenic mice susceptible to poliovirus | Q24564214 | ||
| RNA virus error catastrophe: direct molecular test by using ribavirin | Q24599371 | ||
| Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus | Q27469901 | ||
| Interaction of the poliovirus receptor with poliovirus | Q27620834 | ||
| Genetics of poliovirus | Q29618552 | ||
| Genome variability and capsid structural constraints of hepatitis a virus | Q30165022 | ||
| Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template | Q33960127 | ||
| Codon bias and heterologous protein expression | Q33979754 | ||
| Cell-free, de novo synthesis of poliovirus | Q33995010 | ||
| A compendium of gene expression in normal human tissues | Q34107680 | ||
| Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region. | Q34545765 | ||
| Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase | Q35598774 | ||
| A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells | Q35864616 | ||
| Cold-adapted poliovirus mutants bypass a postentry replication block | Q35887086 | ||
| Complementation of a poliovirus defective genome by a recombinant vaccinia virus which provides poliovirus P1 capsid precursor in trans | Q36649283 | ||
| Replication of poliovirus RNA containing two VPg coding sequences leads to a specific deletion event | Q36652292 | ||
| Construction of a poliovirus type 1/type 2 antigenic hybrid by manipulation of neutralization antigenic site II. | Q36832245 | ||
| Construction and characterization of poliovirus subgenomic replicons | Q36866871 | ||
| Tissue-specific codon usage and the expression of human genes | Q37494068 | ||
| Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication | Q38327453 | ||
| Poliovirus induces apoptosis in the mouse central nervous system | Q39594895 | ||
| The major apoptotic pathway activated and suppressed by poliovirus. | Q39698264 | ||
| Apoptosis-inducing and apoptosis-preventing functions of poliovirus. | Q39868849 | ||
| Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis | Q40110327 | ||
| Internal ribosomal entry site scanning of the poliovirus polyprotein: implications for proteolytic processing | Q42684063 | ||
| The ratio of physical particles per infectious unit observed for poliomyelitis viruses | Q44000476 | ||
| Towards development of an in vitro translation test for poliovirus neurovirulence. | Q44944975 | ||
| The adsorption and early fate of purified poliovirus in HeLa cells | Q45150277 | ||
| Proteolytic Cleavage of the p65-RelA Subunit of NF-κB during Poliovirus Infection | Q58664420 | ||
| The genomes of attenuated and virulent poliovirus strains differ in their in vitro translation efficiencies | Q70116853 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | infectivity | Q1662346 |
| Poliovirus | Q70923324 | ||
| P304 | page(s) | 9687-9696 | |
| P577 | publication date | 2006-10-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity | |
| P478 | volume | 80 |
| Q25938826 | A Detailed Comparative Analysis of Codon Usage Bias in Zika Virus |
| Q89881601 | A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene |
| Q37174393 | A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats |
| Q36281179 | A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection |
| Q37695694 | A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines. |
| Q45369328 | A detailed comparative analysis on the overall codon usage patterns in hepatitis A virus |
| Q35077681 | A host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO). |
| Q57000842 | A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus |
| Q35948053 | An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys. |
| Q95266532 | Analysis of Codon Usage and Nucleotide Bias in Middle East Respiratory Syndrome Coronavirus Genes |
| Q64925905 | Analysis of Nipah Virus Codon Usage and Adaptation to Hosts. |
| Q45359758 | Analysis of base and codon usage by rubella virus |
| Q24612009 | Analysis of codon usage and nucleotide composition bias in polioviruses |
| Q96961116 | Analysis of codon usage bias in potato virus Y non-recombinant strains |
| Q39641659 | Analysis of the synonymous codon usage bias in recently emerged enterovirus D68 strains |
| Q42016334 | Analysis of the use of codon pairs in the HE gene of the ISA virus shows a correlation between bias in HPR codon-pair use and mortality rates caused by the virus. |
| Q37244668 | Antagonistic relationships between intron content and codon usage bias of genes in three mosquito species: functional and evolutionary implications |
| Q90924607 | Attenuate Newcastle disease virus by codon modification of the glycoproteins and phosphoprotein genes |
| Q64917167 | Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding. |
| Q50176831 | Attenuation of Marek's disease virus by codon pair deoptimization of a core gene |
| Q90747705 | Attenuation of Viruses by Large-Scale Recoding of their Genomes: the Selection Is Always Biased |
| Q89995845 | Attenuation of a dengue virus replicon by codon deoptimization of nonstructural genes |
| Q47548276 | Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization. |
| Q35143637 | Attenuation of tick-borne encephalitis virus using large-scale random codon re-encoding |
| Q34252998 | Bicluster pattern of codon context usages between flavivirus and vector mosquito Aedes aegypti: relevance to infection and transcriptional response of mosquito genes |
| Q41111361 | Bioinformatics analysis of codon usage patterns and influencing factors in Penaeus monodon nudivirus |
| Q28473368 | CRPV genomes with synonymous codon optimizations in the CRPV E7 gene show phenotypic differences in growth and altered immunity upon E7 vaccination |
| Q37053465 | Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture |
| Q40889513 | Changing the Codon Usage of hfq Gene has Profound Effect on Phenotype and Pathogenicity of Salmonella Typhimurium |
| Q40749931 | Characterization of codon usage pattern and influencing factors in Japanese encephalitis virus |
| Q40048407 | Characterization of significant molecular determinants of virulence of Enterovirus 71 sub-genotype B4 in Rhabdomyosarcoma cells. |
| Q91593119 | Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility |
| Q38118022 | Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy |
| Q66680685 | Codon Usage Bias Analysis of : Higher Codon Adaptation to Host |
| Q40640181 | Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness |
| Q36831318 | Codon usage and replicative strategies of hepatitis A virus. |
| Q34033113 | Codon usage bias: causative factors, quantification methods and genome-wide patterns: with emphasis on insect genomes |
| Q39243651 | Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus |
| Q89612388 | Codon usage pattern and its influencing factors in different genomes of hepadnaviruses |
| Q37238804 | CodonShuffle: a tool for generating and analyzing synonymously mutated sequences |
| Q56396171 | Combinatorial Approaches to Viral Attenuation |
| Q35180550 | Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. |
| Q35487706 | Development of live-attenuated arenavirus vaccines based on codon deoptimization |
| Q37546745 | Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein. |
| Q26782411 | Development of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genes |
| Q38985722 | Dinucleotide Composition in Animal RNA Viruses Is Shaped More by Virus Family than by Host Species |
| Q28475329 | Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis |
| Q36371484 | Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells. |
| Q42177139 | Divergence and codon usage bias of Betanodavirus, a neurotropic pathogen in fish |
| Q35869278 | Downregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines. |
| Q34261625 | Effect of formaldehyde inactivation on poliovirus |
| Q52655516 | Emergency Services of Viral RNAs: Repair and Remodeling. |
| Q45397402 | Engineering attenuated virus vaccines by controlling replication fidelity |
| Q93161920 | Enterovirus A71 Containing Codon-Deoptimized VP1 and High-Fidelity Polymerase as Next-Generation Vaccine Candidate |
| Q51115385 | Eradicating infectious disease using weakly transmissible vaccines. |
| Q58580089 | Evolution of Codon Usage Bias in Henipaviruses Is Governed by Natural Selection and Is Host-Specific |
| Q39301374 | Evolution of codon usage in Zika virus genomes is host and vector specific |
| Q41582472 | Evolution of codon usage in the smallest photosynthetic eukaryotes and their giant viruses |
| Q42195873 | Evolution of the vesicular stomatitis viruses: divergence and codon usage bias |
| Q42288506 | Evolutionarily stable attenuation by genome rearrangement in a virus |
| Q93088963 | Evolutionary and Structural Overview of Human Picornavirus Capsid Antibody Evasion |
| Q59350091 | Evolutionary changes of the novel Influenza D virus hemagglutinin-esterase fusion gene revealed by the codon usage pattern |
| Q36738542 | Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it? |
| Q26770055 | Exploiting tRNAs to Boost Virulence |
| Q56000614 | Exploratory re-encoding of yellow fever virus genome: new insights for the design of live-attenuated viruses |
| Q90191922 | Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2 |
| Q57009189 | Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes |
| Q35223162 | FRESCo: finding regions of excess synonymous constraint in diverse viruses |
| Q21131562 | Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid |
| Q92702312 | Foot-and-Mouth Disease Virus: Immunobiology, Advances in Vaccines and Vaccination Strategies Addressing Vaccine Failures-An Indian Perspective |
| Q39063658 | Foot-and-mouth disease vaccines |
| Q30384947 | Further studies on the role of the residue 890 cysteine to tyrosine mutation in the M70 primase ORF of the temperature-sensitive mutant (tsm5) of murine cytomegalovirus. |
| Q39097131 | General Molecular Strategy for Development of Arenavirus Live-Attenuated Vaccines |
| Q36208109 | Generation of Live Attenuated Influenza Virus by Using Codon Usage Bias. |
| Q66679644 | Genetic Analysis and Evolutionary Changes of the Torque teno sus Virus |
| Q63246462 | Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus |
| Q40075092 | Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution. |
| Q52565499 | Genetic and evolutionary analysis of emerging H3N2 canine influenza virus. |
| Q37355985 | Genetic inactivation of poliovirus infectivity by increasing the frequencies of CpG and UpA dinucleotides within and across synonymous capsid region codons. |
| Q37599051 | Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure |
| Q40156530 | Genome dynamics and evolution of codon usage patterns in shrimp viruses |
| Q45355922 | Genome dynamics in three different geographical isolates of white spot syndrome virus (WSSV). |
| Q35111153 | Genome-wide analysis of codon usage and influencing factors in chikungunya viruses |
| Q40156393 | Genome-wide analysis of codon usage bias in Bovine Coronavirus. |
| Q40180474 | Genome-wide analysis of codon usage bias in Ebolavirus |
| Q40147388 | Genome-wide analysis of synonymous codon usage in Huaiyangshan virus and other bunyaviruses |
| Q42256229 | Genomic adaptation of the ISA virus to Salmo salar codon usage. |
| Q35755118 | Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution |
| Q42056724 | Global RNA structure analysis of poliovirus identifies a conserved RNA structure involved in viral replication and infectivity |
| Q58861509 | HIV-1 Protease Evolvability Is Affected by Synonymous Nucleotide Recoding |
| Q41509938 | HP-PRRSV is attenuated by de-optimization of codon pair bias in its RNA-dependent RNA polymerase nsp9 gene. |
| Q53274540 | Hepatitis A Virus Codon Usage: Implications for Translation Kinetics and Capsid Folding. |
| Q38860688 | Hepatitis A virus adaptation to cellular shutoff is driven by dynamic adjustments of codon usage and results in the selection of populations with altered capsids |
| Q79450580 | Host-related nucleotide composition and codon usage as driving forces in the recent evolution of the Astroviridae |
| Q36108268 | Human body temperature and new approaches to constructing temperature-sensitive bacterial vaccines |
| Q34585689 | Identification and manipulation of the molecular determinants influencing poliovirus recombination |
| Q34293577 | Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design |
| Q39643750 | Improved recombinant protein yield using a codon deoptimized DHFR selectable marker in a CHEF1 expression plasmid |
| Q40494008 | Improving virus production through quasispecies genomic selection and molecular breeding. |
| Q34808109 | Infectious Bronchitis Virus as a Vector for the Expression of Heterologous Genes |
| Q58703500 | Insights into the genetic and host adaptability of emerging porcine circovirus 3 |
| Q59353229 | Large-Scale Synonymous Substitutions in Cucumber Mosaic Virus RNA 3 Facilitate Amino Acid Mutations in the Coat Protein |
| Q43504569 | Large-scale codon de-optimisation of the p29 replicase gene by synonymous substitutions causes a loss of infectivity of melon necrotic spot virus. |
| Q34417984 | Large-scale de novo DNA synthesis: technologies and applications |
| Q37713911 | Large-scale nucleotide optimization of simian immunodeficiency virus reduces its capacity to stimulate type I interferon in vitro |
| Q35484845 | Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference |
| Q41925331 | Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes |
| Q30390286 | Live attenuated influenza virus vaccines by computer-aided rational design |
| Q64102124 | Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications |
| Q45373595 | Modelling foot-and-mouth disease virus dynamics in oral epithelium to help identify the determinants of lysis. |
| Q33953331 | Mutational and fitness landscapes of an RNA virus revealed through population sequencing |
| Q37001439 | New generation of inactivated poliovirus vaccines for universal immunization after eradication of poliomyelitis |
| Q64116962 | Novel Approaches for The Development of Live Attenuated Influenza Vaccines |
| Q38818648 | Novel strategies for development of hemorrhagic fever arenavirus live-attenuated vaccines. |
| Q97597462 | On the correct interpretation of similarity index in codon usage studies: comparison with four other metrics and implications for Zika and West Nile virus |
| Q98224708 | Origin and Evolution of H1N1/pdm2009: A Codon Usage Perspective |
| Q30423323 | Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development |
| Q34297832 | Picornavirus morphogenesis |
| Q42402704 | Poliovirus evolution: the strong, silent type |
| Q40005126 | Poliovirus: generation and characterization of mutants |
| Q34674160 | Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO). |
| Q42287635 | Potential roles of synonymous codon usage and tRNA concentration in hosts on the two initiation regions of foot-and-mouth disease virus RNA. |
| Q24650468 | Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis |
| Q37687662 | Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to viruses |
| Q33548140 | RCDI/eRCDI: a web-server to estimate codon usage deoptimization. |
| Q33963398 | RNA virus reverse genetics and vaccine design. |
| Q39633419 | Rabies virus (RV) glycoprotein expression levels are not critical for pathogenicity of RV. |
| Q31111619 | Random codon re-encoding induces stable reduction of replicative fitness of Chikungunya virus in primate and mosquito cells |
| Q34119676 | Rationalizing the development of live attenuated virus vaccines |
| Q38775660 | Recoding structural glycoprotein E2 in classical swine fever virus (CSFV) produces complete virus attenuation in swine and protects infected animals against disease |
| Q57989514 | Recombinant Live Vaccines to Protect Against the Severe Acute Respiratory Syndrome Coronavirus |
| Q40126775 | Reduced Protein Expression in a Virus Attenuated by Codon Deoptimization. |
| Q34237741 | Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes |
| Q27309749 | Rescue of recent virulent and avirulent field strains of bluetongue virus by reverse genetics |
| Q38028997 | Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis |
| Q40544770 | Role of host-driven mutagenesis in determining genome evolution of sigma virus (DMelSV; Rhabdoviridae) in Drosophila melanogaster |
| Q95623520 | Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design |
| Q99710848 | Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design |
| Q39011114 | Sequence-Specific Sensing of Nucleic Acids |
| Q36278215 | Slow fitness recovery in a codon-modified viral genome |
| Q47549808 | Structural divergence creates new functional features in alphavirus genomes. |
| Q52646113 | SuPReMe: a rapid reverse genetics method to generate clonal populations of recombinant RNA viruses. |
| Q36481497 | Synonymous Deoptimization of Foot-and-Mouth Disease Virus Causes Attenuation In Vivo while Inducing a Strong Neutralizing Antibody Response |
| Q42114403 | Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus |
| Q90477207 | Synonymous genome recoding: a tool to explore microbial biology and new therapeutic strategies |
| Q38951951 | Synthetic gene design-The rationale for codon optimization and implications for molecular pharming in plants. |
| Q24650817 | Synthetic viruses: a new opportunity to understand and prevent viral disease |
| Q38203513 | Tailoring the Immune Response via Customization of Pathogen Gene Expression. |
| Q91765509 | The Critical Role of Codon Composition on the Translation Efficiency Robustness of the Hepatitis A Virus Capsid |
| Q92153856 | The Deoptimization of Rabies Virus Matrix Protein Impacts Viral Transcription and Replication |
| Q55236878 | The Evolution of Molecular Compatibility between Bacteriophage ΦX174 and its Host. |
| Q84230593 | The Pathogenesis and Prevention of Encephalitis due to Human Enterovirus 71 |
| Q56556115 | The adaptation of codon usage of +ssRNA viruses to their hosts |
| Q45368444 | The characteristics of the synonymous codon usage in enterovirus 71 virus and the effects of host on the virus in codon usage pattern |
| Q35779770 | The characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern |
| Q24498611 | The distribution of synonymous codon choice in the translation initiation region of dengue virus |
| Q38735720 | The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication. |
| Q91651456 | The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides |
| Q38092577 | The role of mutational robustness in RNA virus evolution |
| Q33525509 | The systemic imprint of growth and its uses in ecological (meta)genomics |
| Q40283260 | Translational selection of genes coding for perfectly conserved proteins among three mosquito vectors |
| Q47443226 | Transmissible Viral Vaccines |
| Q38848322 | Unique safety issues associated with virus-vectored vaccines: Potential for and theoretical consequences of recombination with wild type virus strains |
| Q54223297 | Universal evolutionary selection for high dimensional silent patterns of information hidden in the redundancy of viral genetic code. |
| Q27468852 | Utilisation of ISA Reverse Genetics and Large-Scale Random Codon Re-Encoding to Produce Attenuated Strains of Tick-Borne Encephalitis Virus within Days |
| Q27490454 | Vaccines: the Fourth Century |
| Q91841209 | Variation in base composition underlies functional and evolutionary divergence in non-LTR retrotransposons |
| Q37425283 | Viral adaptation to host: a proteome-based analysis of codon usage and amino acid preferences |
| Q38554795 | Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology |
| Q24644457 | Virus attenuation by genome-scale changes in codon pair bias |
| Q56339878 | Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models |
| Q42149676 | sIPV process development for costs reduction |
Search more.