Dicer promotes transcription termination at sites of replication stress to maintain genome stability

scientific article

Dicer promotes transcription termination at sites of replication stress to maintain genome stability is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CELL.2014.09.031
P932PMC publication ID4243041
P698PubMed publication ID25417108
P5875ResearchGate publication ID268789253

P50authorRobert Anthony MartienssenQ21165568
P2093author name stringSonali Bhattacharjee
Francisco Antequera
Mar Sánchez
Jie Ren
Stephane E Castel
Alberto Valbuena
An-Yun Chang
P2860cites workRecombination Regulation by Transcription-Induced Cohesin Dissociation in rDNA RepeatsQ22065794
Mapping genomic hotspots of DNA damage by a single-strand-DNA-compatible and strand-specific ChIP-seq method.Q36732471
Transcriptional termination enhances protein expression in human cellsQ37251886
Dicer, Drosha, and outcomes in patients with ovarian cancerQ37262584
Dicer1 functions as a haploinsufficient tumor suppressorQ37457958
Silent chromatin at the middle and ends: lessons from yeastsQ37560585
On the connection between RNAi and heterochromatin at centromeresQ37834837
Unravelling the means to an end: RNA polymerase II transcription termination.Q37864536
miRNA processing and human cancer: DICER1 cuts the mustardQ37963628
RNA and epigenetic silencing: Insight from fission yeastQ37965791
Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcriptionQ37998652
Ribosomal DNA and cellular senescence: new evidence supporting the connection between rDNA and agingQ38174325
Coordination of DNA replication and histone modification by the Rik1-Dos2 complexQ38267644
The two steps of poly(A)-dependent termination, pausing and release, can be uncoupled by truncation of the RNA polymerase II carboxyl-terminal repeat domainQ40815653
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivoQ41455736
Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription.Q41473315
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiaeQ41843323
Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombeQ41858295
Lsd1 and lsd2 control programmed replication fork pauses and imprinting in fission yeastQ41904552
The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability.Q41945851
Autoregulation of convergent RNAi genes in fission yeast.Q42008783
Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.Q42152387
RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II.Q42228801
Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatinQ42524806
Chromatin-associated RNA interference components contribute to transcriptional regulation in DrosophilaQ42721062
RNA polymerase modulators and DNA repair activities resolve conflicts between DNA replication and transcriptionQ46615071
Cohesin complex promotes transcriptional termination between convergent genes in S. pombeQ46688659
Cell cycle control of centromeric repeat transcription and heterochromatin assemblyQ46793624
Argonaute and Triman generate dicer-independent priRNAs and mature siRNAs to initiate heterochromatin formation.Q46987001
Cotranscriptional role for Arabidopsis DICER-LIKE 4 in transcription terminationQ51798265
Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombeQ53283775
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencingQ53619809
S. pombe LSD1 Homologs Regulate Heterochromatin Propagation and Euchromatic Gene TranscriptionQ57539961
Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template ExchangeQ59198307
Ribosomal DNA Replication in the Fission Yeast, Schizosaccharomyces pombeQ74147239
Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAiQ80688207
Human rRNA gene clusters are recombinational hotspots in cancerQ84917064
Establishing, maintaining and modifying DNA methylation patterns in plants and animalsQ24630397
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.Q27932277
Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genesQ27935087
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAiQ28218870
Argonaute slicing is required for heterochromatic silencing and spreadingQ28260028
Feedback Regulation of Transcriptional Termination by the Mammalian Circadian Clock PERIOD ComplexQ28507441
Transcription-coupled DNA repair: two decades of progress and surprisesQ29614662
An unusual form of transcriptional silencing in yeast ribosomal DNAQ29618831
Quelling targets the rDNA locus and functions in rDNA copy number controlQ33412565
H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stabilityQ33641829
Dicer is associated with ribosomal DNA chromatin in mammalian cellsQ33668649
Global effects on gene expression in fission yeast by silencing and RNA interference machineries.Q33694831
RNAi and heterochromatin repress centromeric meiotic recombinationQ33928327
Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeastQ34014307
DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation.Q34030430
Yeast Sen1 helicase protects the genome from transcription-associated instability.Q34157855
RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome InstabilityQ34242729
R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island PromotersQ34258378
R Loops: From Transcription Byproducts to Threats to Genome StabilityQ34271508
Gene Q antiterminator proteins of Escherichia coli phages 82 and lambda suppress pausing by RNA polymerase at a rho-dependent terminator and at other sitesQ34289834
The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phaseQ34328931
RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyondQ34385616
RNAi-dependent formation of heterochromatin and its diverse functionsQ34422701
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencingQ34456753
Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeastQ35126538
Determinants of heterochromatic siRNA biogenesis and functionQ35171295
TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathwayQ35618796
DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.Q35860068
RNAi keeps Atf1-bound stress response genes in check at nuclear poresQ35882142
RNAi triggered by specialized machinery silences developmental genes and retrotransposonsQ36561712
Homologous recombination as a mechanism to recognize repetitive DNA sequences in an RNAi pathwayQ36592389
piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germlineQ36684944
RNA interference guides histone modification during the S phase of chromosomal replication.Q36692156
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectgenome stabilityQ98655700
regulation of termination of RNA polymerase II transcriptionQ22253571
positive regulation of termination of RNA polymerase II transcriptionQ22253572
P304page(s)572-583
P577publication date2014-10-16
P1433published inCellQ655814
P1476titleDicer promotes transcription termination at sites of replication stress to maintain genome stability
P478volume159

Reverse relations

cites work (P2860)
Q368622132D-DIGE-based proteome expression changes in leaves of rice seedlings exposed to low-level gamma radiation at Iitate village, Fukushima
Q35113562A deeply conserved, noncanonical miRNA hosted by ribosomal DNA.
Q28083645A model for the control of DNA integrity by the sperm nuclear matrix
Q49576014Accumulation of RNA on chromatin disrupts heterochromatic silencing
Q59312641Bases of antisense lncRNA-associated regulation of gene expression in fission yeast
Q60915920CRISPR-Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics
Q28066464Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer
Q57456667Combination therapy to checkmate Glioblastoma: clinical challenges and advances
Q90726463Condensin locates at transcriptional termination sites in mitosis, possibly releasing mitotic transcripts
Q39027290Conflict Resolution in the Genome: How Transcription and Replication Make It Work
Q89686824Conserved chromosomal functions of RNA interference
Q37727855Cross-Regulation between Transposable Elements and Host DNA Replication
Q48192240DNA-RNA hybrids: the risks of DNA breakage during transcription
Q36997913Dicer in action at replication-transcription collisions
Q92005586Dicer prevents genome instability in response to replication stress
Q40045747Dicer regulates non-homologous end joining and is associated with chemosensitivity in colon cancer patients.
Q41348887Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR-324-5p mediated suppression of HMGXB3 and WASF-2.
Q54967259Distinct 'safe zones' at the nuclear envelope ensure robust replication of heterochromatic chromosome regions.
Q36959177Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast
Q49549364Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair.
Q49838567Enhancer of polycomb maintains germline activity and genome integrity in Drosophila testis
Q100558661Evolution of DNA replication origin specification and gene silencing mechanisms
Q37062444Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice
Q58862336From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
Q92624759Human germ cell tumours from a developmental perspective
Q90575517Keeping ribosomal DNA intact: a repeating challenge
Q38651215Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation.
Q35173293Mechanism of siRNA production from repetitive DNA
Q52321974Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.
Q36677081MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.
Q42257614New roles for Dicer in the nucleolus and its relevance to cancer
Q64388860Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks
Q89659307Nuclear Argonaute Piwi Gene Mutation Affects rRNA by Inducing rRNA Fragment Accumulation, Antisense Expression, and Defective Processing in Drosophila Ovaries
Q41343667Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage
Q26797870Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus
Q36368469R loops regulate promoter-proximal chromatin architecture and cellular differentiation
Q74441822RNA interference hangs by a thread
Q51396383RNA interference is essential for cellular quiescence
Q41109745RNA pol II transcript abundance controls condensin accumulation at mitotically up-regulated and heat-shock-inducible genes in fission yeast
Q52589225RNAi drives nonreciprocal translocations at eroding chromosome ends to establish telomere-free linear chromosomes
Q58773614Rare Genetic Diseases with Defects in DNA Repair: Opportunities and Challenges in Orphan Drug Development for Targeted Cancer Therapy
Q26740715Recent advances in understanding transcription termination by RNA polymerase II
Q39168142Regulation of DNA Replication through Natural  Impediments in the Eukaryotic Genome.
Q26860970Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability
Q47122778Small RNA-mediated regulation of DNA dosage in the ciliate Oxytricha
Q47820263Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics
Q49386189The Affinity of the S9.6 Antibody for Double-Stranded RNAs Impacts the Accurate Mapping of R-Loops in Fission Yeast
Q55077869The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity.
Q39149348The emerging role of RNAs in DNA damage repair
Q41893185The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements.
Q91698339The molecular landscape of ETMR at diagnosis and relapse
Q92254240Transcription-mediated replication hindrance: a major driver of genome instability
Q38994629Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond
Q38902434Transcription-replication conflicts: how they occur and how they are resolved
Q38789767Transcriptional reprogramming in cellular quiescence
Q36394957tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription.

Search more.