Excess cholesterol induces mouse egg activation and may cause female infertility.

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Excess cholesterol induces mouse egg activation and may cause female infertility. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111E4972Y
P356DOI10.1073/PNAS.1418954111
P932PMC publication ID4246315
P698PubMed publication ID25368174
P5875ResearchGate publication ID267813241

P50authorGregoriy A DokshinQ57334389
P2093author name stringLi Wang
Ayce Yesilaltay
Monty Krieger
Nava Dekel
David C Page
David F Albertini
Dalia Galiani
Eliza Vasile
Dolores Busso
Ruth Shalgi
Tony Chavarria
Attilio Rigotti
Dalia Walzer
Juan Andrés Orellana
Linda Quilaqueo
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Caffeine alleviates the deterioration of Ca(2+) release mechanisms and fragmentation of in vitro-aged mouse eggsQ35581466
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Historical walk: the HRP Special Programme and infertilityQ39521170
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Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolismQ40709438
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Full-term mouse development by abolishing Zn2+-dependent metaphase II arrest without Ca2+ releaseQ42998087
Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathwayQ43726505
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Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.Q43893087
Intracellular calcium oscillations signal apoptosis rather than activation in in vitro aged mouse eggsQ44000528
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophagesQ44542540
Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolismQ44995908
Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in miceQ45020519
Mouse oocytes gradually develop the capacity for activation during the metaphase II arrestQ45369934
Free cholesterol overloading induced smooth muscle cells death and activated both ER- and mitochondrial-dependent death pathway.Q45997661
HDL cholesterol levels are an important factor for determining the lifespan of erythrocytesQ46786279
Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells.Q46876617
Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertilityQ46892860
Efficient strontium-induced activation of mouse oocytes in standard culture media by chelating calcium.Q46949112
Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient miceQ48668563
Cellular and genetic analysis of oocytes and embryos in a human case of spontaneous oocyte activationQ48683616
Brefeldin A disrupts asymmetric spindle positioning in mouse oocytesQ48771441
Inhibition of MEK or cdc2 kinase parthenogenetically activates mouse eggs and yields the same phenotypes as Mos(-/-) parthenogenotes.Q48857930
Haploidy but not parthenogenetic activation leads to increased incidence of apoptosis in mouse embryosQ48872912
Characterization of oocyte and follicle development in growth differentiation factor-9-deficient miceQ48925544
Meiotic abnormalities of c-mos knockout mouse oocytes: activation after first meiosis or entrance into third meiotic metaphaseQ48971405
Association of lower plasma estradiol levels and low expression of scavenger receptor class B, type I in infertile women.Q50650703
Egg activation events are regulated by the duration of a sustained [Ca2+]cyt signal in the mouse.Q50661486
Oocyte-granulosa cell heterologous gap junctions are required for the coordination of nuclear and cytoplasmic meiotic competence.Q50722741
Clinical impact of scavenger receptor class B type I gene polymorphisms on human female fertility.Q51469653
Cholesteryl ester transfer protein (CETP) expression protects against diet induced atherosclerosis in SR-BI deficient mice.Q51768378
Parthenogenetic activation of mouse oocytes in vitro with ethanol and benzyl alcohol.Q51853896
The absence of a Ca(2+) signal during mouse egg activation can affect parthenogenetic preimplantation development, gene expression patterns, and blastocyst quality.Q52013417
Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: role of negatively charged phospholipids.Q54613595
Free Ca2+ increases in exponential phases during mouse oocyte activationQ59092897
Repetitive calcium transients and the role of calcium in exocytosis and cell cycle activation in the mouse eggQ67721277
Strontium supports capacitation and the acrosome reaction in mouse sperm and rapidly activates mouse eggsQ68851062
Proteins of human follicular fluid: the blood-follicle barrierQ69997939
Lipoprotein and phospholipid distribution in human follicular fluidsQ70072155
Biochemical characterization of pre-beta 1 high-density lipoprotein from human ovarian follicular fluid: evidence for the presence of a lipid coreQ71087321
Release of mouse eggs from metaphase arrest by protein synthesis inhibition in the absence of a calcium signal or microtubule assemblyQ72007956
Follicular fluid lipoproteins in the mare: evaluation of HDL transfer from plasma to follicular fluidQ72705829
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)E4972-80
P577publication date2014-11-03
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleExcess cholesterol induces mouse egg activation and may cause female infertility
P478volume111

Reverse relations

cites work (P2860)
Q93162536Anti-oxidative function of follicular fluid HDL and outcomes of modified natural cycle-IVF
Q33435708Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease
Q98196686Facial appearance and metabolic health biomarkers in women
Q33883892Free cholesterol and cholesterol esters in bovine oocytes: Implications in survival and membrane raft organization after cryopreservation
Q41522674Liposome-encapsulated diacyl glycerol and inositol triphosphate-induced delayed oocyte activation and poor development of parthenotes.
Q64884005Liver X Receptors: A Possible Link between Lipid Disorders and Female Infertility.
Q41026512MAPK3/1 (ERK1/2) and Myosin Light Chain Kinase in Mammalian Eggs Affect Myosin-II Function and Regulate the Metaphase II State in a Calcium- and Zinc-Dependent Manner.
Q94518190Molecular analysis of lipid uptake- and necroptosis-associated factor expression in vitrified-warmed mouse oocytes
Q47241403Scavenger Receptor Type B1 and Lipoprotein Nanoparticle Inhibit Myeloid Derived Suppressor Cells
Q46270727The function of HDL and LDL in the maintenance of mouse ovarian steroid balance

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