IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity.

scientific article

IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1024217166
P356DOI10.1007/S12026-007-0022-2
P698PubMed publication ID17917016

P50authorHans D. OchsQ115437
Troy R TorgersonQ96130732
Eleonora GambineriQ43300293
P2860cites workDisruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseQ24290693
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activationQ24291515
FOXP3 controls regulatory T cell function through cooperation with NFATQ24298179
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cellsQ24298812
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressorQ24300325
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cellsQ24306205
X-Linked syndrome of polyendocrinopathy, immune dysfunction, and diarrhea maps to Xp11.23-Xq13.3.Q24539046
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndromeQ24626901
Treatment of the Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome (IPEX) by Allogeneic Bone Marrow TransplantationQ56941507
A new case of IPEX receiving bone marrow transplantationQ58800451
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell levelQ60311694
Could protracted diarrhoea of infancy have an autoimmune pathogenesis?Q72526144
Congenital autoimmune diabetes mellitusQ73810945
A 75-kD autoantigen recognized by sera from patients with X-linked autoimmune enteropathy associated with nephropathyQ74404652
A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndromeQ77091536
Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cellsQ81577003
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndromeQ24679039
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
The amount of scurfin protein determines peripheral T cell number and responsivenessQ28504592
Winged helix proteinsQ29617630
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
Forkhead transcription factors: key players in development and metabolismQ29618804
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfyQ29619109
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Q29619324
Manifestations and linkage analysis in X-linked autoimmunity-immunodeficiency syndromeQ30305447
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) associated with pemphigoid nodularis: a case report and review of the literatureQ30440761
Identification of an autoimmune enteropathy-related 75-kilodalton antigenQ30779073
Neonatal diabetes mellitus, enteropathy, thrombocytopenia, and endocrinopathy: Further evidence for an X-linked lethal syndrome.Q33336778
Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndromeQ33360497
Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: implications for autoimmunity and tumor immunityQ34374572
Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-toleranceQ34503328
CD4+ CD25+ suppressor T cells: more questions than answersQ34716304
Regulatory T cells in transplantation toleranceQ35092535
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasisQ35159540
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host diseaseQ35848361
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.Q36078042
CD4+ regulatory T cells: mechanisms of induction and effector function.Q36281207
Cd4+Cd25+ regulatory T cells and their therapeutic potentialQ36366885
Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinomaQ40436418
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cellsQ40498116
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigenQ40701079
Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation.Q44509623
In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunityQ45884432
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabineQ46508260
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancerQ46549031
Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome).Q46673023
Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cellsQ47339163
Abnormalities of CD4 T cell subpopulations in ANCA-associated vasculitis.Q51993610
Functional CD25– and CD25+ mucosal regulatory T cells are induced in gut‐draining lymphoid tissue within 48 h after oral antigen applicationQ52005392
Successful bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning.Q52573741
An X-linked syndrome of diarrhea, polyendocrinopathy, and fatal infection in infancy.Q55062928
Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigenQ56902816
Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cellsQ56903036
Anti-tumor immunity and autoimmunity: a balancing act of regulatory T cellsQ56903547
Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administrationQ56904883
P433issue1-3
P304page(s)112-121
P577publication date2007-01-01
P1433published inImmunologic ResearchQ15754981
P1476titleIPEX, FOXP3 and regulatory T-cells: a model for autoimmunity
P478volume38

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