Mutagenesis and more: umuDC and the Escherichia coli SOS response

scientific article

Mutagenesis and more: umuDC and the Escherichia coli SOS response is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1093/GENETICS/148.4.1599
P932PMC publication ID1460076
P698PubMed publication ID9560379

P2093author name stringG C Walker
Graham C Walker
Bradley T Smith
B T Smith
P2860cites workApplications and statistics for multiple high-scoring segments in molecular sequencesQ24562524
Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmidsQ24564599
Autodigestion of lexA and phage lambda repressorsQ24597460
The structure of the E. coli recA protein monomer and polymerQ27643868
The UmuD' protein filament and its potential role in damage induced mutagenesisQ27734343
Deoxycytidyl transferase activity of yeast REV1 proteinQ27931173
Mutants of yeast defective in mutation induced by ultraviolet lightQ27935336
Thymine-thymine dimer bypass by yeast DNA polymerase zetaQ27938043
FtsZ ring structure associated with division in Escherichia coliQ28245159
SOS-regulated proteins in translesion DNA synthesis and mutagenesisQ28271489
Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressorQ33213023
RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.Q33559613
UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.Q33559649
Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vectorQ33663733
Overproduction of the epsilon subunit of DNA polymerase III counteracts the SOS mutagenic response of Escherichia coliQ33680263
cAMP-dependent SOS induction and mutagenesis in resting bacterial populations.Q33719467
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesisQ33798128
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS systemQ34144983
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.Q34305929
Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coliQ34331982
Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coliQ34349964
DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesisQ34631905
Purified lexA protein is a repressor of the recA and lexA genesQ35398169
Mechanism of action of the lexA gene productQ35398282
A new Escherichia coli cell division gene, ftsKQ35597632
Specific in vivo protein-protein interactions between Escherichia coli SOS mutagenesis proteinsQ35606522
Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB geneQ35608675
The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesisQ35610220
Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approachQ35618214
sfi-independent filamentation in Escherichia coli Is lexA dependent and requires DNA damage for inductionQ35620975
The Fis protein: it's not just for DNA inversion anymoreQ35658496
Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vectorQ35837992
A monocysteine approach for probing the structure and interactions of the UmuD proteinQ35967829
UV mutagenesis in Salmonella typhimurium is umuDC dependent despite the presence of samABQ36111224
Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutantsQ36111483
Salmonella typhimurium has two homologous but different umuDC operons: cloning of a new umuDC-like operon (samAB) present in a 60-megadalton cryptic plasmid of S. typhimuriumQ36129503
Mutagenic DNA repair in Escherichia coli. XVI. Mutagenesis by ultraviolet light plus delayed photoreversal in recA strains.Q54750574
Mutagenic DNA repair in Escherichia coli. XIX. On the roles of RecA protein in ultraviolet light mutagenesisQ68000989
Mechanism of transient inhibition of DNA synthesis in ultraviolet-irradiated E. coli: inhibition is independent of recA whilst recovery requires RecA protein itself and an additional, inducible SOS functionQ69893640
Mutagenic repair in Escherichia coli. X. The umuC gene product may be required for replication past pyrimidine dimers but not for the coding error in UV-mutagenesisQ72398800
Relative probability of mutagenic translesion synthesis on the leading and lagging strands during replication of UV-irradiated DNA in a human cell extractQ72551652
Mutational analysis of the RecA protein L1 region identifies this area as a probable part of the co-protease substrate binding siteQ73866660
Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesisQ73958830
Interaction of Escherichia coli RecA protein with LexA repressor. I. LexA repressor cleavage is competitive with binding of a secondary DNA moleculeQ93885439
The enhanced mutagenic potential of the MucAB proteins correlates with the highly efficient processing of the MucA proteinQ36132263
Dramatic changes in Fis levels upon nutrient upshift in Escherichia coliQ36137894
Mutagenic DNA repair in enterobacteriaQ36153171
SOS factors involved in translesion synthesisQ36157744
SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cellsQ36160219
The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysisQ36172976
New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesisQ36176522
Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.Q36176656
Biochemical analysis of UV mutagenesis in Escherichia coli by using a cell-free reaction coupled to a bioassay: identification of a DNA repair-dependent, replication-independent pathwayQ36947572
Fidelity mechanisms in DNA replicationQ37285267
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase IIIQ37296938
Requirements for bypass of UV-induced lesions in single-stranded DNA of bacteriophage phi X174 in Salmonella typhimuriumQ37399518
Cellular strategies for accommodating replication-hindering adducts in DNA: control by the SOS response in Escherichia coliQ37441805
umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homologyQ37522339
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coliQ37522356
The thymine-thymine pyrimidine-pyrimidone(6-4) ultraviolet light photoproduct is highly mutagenic and specifically induces 3' thymine-to-cytosine transitions in Escherichia coliQ37612232
Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesisQ37692184
Function of nucleoside triphosphate and polynucleotide in Escherichia coli recA protein-directed cleavage of phage lambda repressorQ38356140
Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA.Q38358001
LexA cleavage and other self-processing reactionsQ39929778
Overproduction of the beta subunit of DNA polymerase III holoenzyme reduces UV mutagenesis in Escherichia coliQ39933704
Are there DNA damage checkpoints in E. coli?Q40498086
Replicational Fidelity: Mechanisms of Mutation Avoidance and Mutation FixationQ41105745
Damage inducible mutagenesis: recent insights into the activities of the Umu family of mutagenesis proteins.Q41284302
Bacterial cell division and the Z ringQ41550173
New mutations in cloned Escherichia coli umuDC genes: novel phenotypes of strains carrying a umuC125 plasmidQ41777536
Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricusQ42641653
Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavageQ43432570
Sequential folding of UmuC by the Hsp70 and Hsp60 chaperone complexes of Escherichia coliQ43560457
A partially deficient mutant, recA1730, that fails to form normal nucleoprotein filamentsQ44679842
Induction kinetics of mutagenic DNA repair activity in E. coli following ultraviolet irradiationQ44943733
Ultraviolet reactivation and ultraviolet mutagenesis of λ in different genetic systemsQ45245860
Interaction of Escherichia coli RecA protein with LexA repressor. II. Inhibition of DNA strand exchange by the uncleavable LexA S119A repressor argues that recombination and SOS induction are competitive processes.Q46031751
Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cellsQ46902807
Arrested DNA replication in Xenopus and release by Escherichia coli mutagenesis proteins.Q50761948
The LexA repressor binds within the deep helical groove of the activated RecA filament.Q52396114
Cloning and characterization of the umu operon responsible for inducible mutagenesis in Escherichia coliQ54493691
Quantitation of the inhibition of Hfr x F- recombination by the mutagenesis complex UmuD'C.Q54562208
In vitro inhibition of RecA-mediated homologous pairing by UmuD'C proteins.Q54619349
In vitro UV mutagenesis associated with nucleotide excision-repair gaps in Escherichia coli.Q54640037
The appearance of the UmuD'C protein complex in Escherichia coli switches repair from homologous recombination to SOS mutagenesis.Q54647706
Construction of a umuDC operon substitution mutation in Escherichia coliQ54682895
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)1599-1610
P577publication date1998-04-01
P1433published inGeneticsQ3100575
P1476titleMutagenesis and More: umuDC and the Escherichia coli SOS Response
Mutagenesis and more: umuDC and the Escherichia coli SOS response
P478volume148

Reverse relations

cites work (P2860)
Q5169790262-kb plasmids harboring rulAB homologues confer UV-tolerance and epiphytic fitness to Pseudomonas syringae pv. syringae mango isolates.
Q35600001A model for a umuDC-dependent prokaryotic DNA damage checkpoint
Q33938065A novel conjugative plasmid from Enterococcus faecalis E99 enhances resistance to ultraviolet radiation
Q33993830A role for the umuDC gene products of Escherichia coli in increasing resistance to DNA damage in stationary phase by inhibiting the transition to exponential growth
Q33900781A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence
Q24597093All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis
Q33991882An operon that confers UV resistance by evoking the SOS mutagenic response in streptococcal conjugative transposon Tn5252.
Q24613731Bacterial charity work leads to population-wide resistance
Q36182449Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA.
Q41960084Characterization of the global transcriptional responses to different types of DNA damage and disruption of replication in Bacillus subtilis
Q91687874Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species
Q24523653DNA polymerase iota and related rad30-like enzymes
Q47293650DNA-repair potential of Halomonas spp. from the Salt Plains Microbial Observatory of Oklahoma
Q38311410Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA.
Q35215746Diverse responses to UV-B radiation and repair mechanisms of bacteria isolated from high-altitude aquatic environments
Q33460495Extremophile culture collection from Andean lakes: extreme pristine environments that host a wide diversity of microorganisms with tolerance to UV radiation
Q56918859Extremophilic Acinetobacter Strains from High-Altitude Lakes in Argentinean Puna: Remarkable UV-B Resistance and Efficient DNA Damage Repair
Q39452803Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase
Q37199542From damaged genome to cell surface: transcriptome changes during bacterial cell death triggered by loss of a restriction-modification gene complex.
Q24631768Historical overview: searching for replication help in all of the rec places
Q40005228Identification of genes that confer sediment fitness to Desulfovibrio desulfuricans G20.
Q35840875Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina
Q42210567Induction of mycobacterial resistance to quinolone class antimicrobials
Q34317246Lack of strand bias in UV-induced mutagenesis in Escherichia coli
Q34756168Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis
Q24631110Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination
Q28205789Mechanism of DNA polymerase II-mediated frameshift mutagenesis
Q44226761Modeling the role of altruism of antibiotic-resistant bacteria
Q33634705Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.
Q28084088Nucleotide excision repair in humans
Q46710323Occurrence of resistance to antibiotics, UV-B, and arsenic in bacteria isolated from extreme environments in high-altitude (above 4400 m) Andean wetlands
Q29619755Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda
Q39501119Regulation of the rulAB mutagenic DNA repair operon of Pseudomonas syringae by UV-B (290 to 320 nanometers) radiation and analysis of rulAB-mediated mutability in vitro and in planta
Q35822001SOS mutator activity: unequal mutagenesis on leading and lagging strands.
Q39488545Sequence diversity of rulA among natural isolates of Pseudomonas syringae and effect on function of rulAB-mediated UV radiation tolerance.
Q34504117Stress-induced evolution and the biosafety of genetically modified microorganisms released into the environment
Q24561825Survival of Shewanella oneidensis MR-1 after UV radiation exposure
Q36538298The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase
Q64929745The phage T4 DNA ligase in vivo improves the survival-coupled bacterial mutagenesis.
Q35159404Transposon stability and a role for conjugational transfer in adaptive mutability

Search more.