Overproduction of the beta subunit of DNA polymerase III holoenzyme reduces UV mutagenesis in Escherichia coli

scientific article published on April 1992

Overproduction of the beta subunit of DNA polymerase III holoenzyme reduces UV mutagenesis in Escherichia coli is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JB.174.8.2517-2524.1992
P932PMC publication ID205890
P698PubMed publication ID1556072

P2093author name stringTadmor Y
Livneh Z
Ascarelli-Goell R
Skaliter R
P2860cites workA temperature-sensitive Escherichia coli mutant defective in DNA replication: dnaA, a new gene adjacent to the dnA, geneQ72856832
Bypass and termination at apurinic sites during replication of single-stranded DNA in vitro: a model for apurinic site mutagenesisQ33631558
Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vectorQ33663733
Overproduction of the epsilon subunit of DNA polymerase III counteracts the SOS mutagenic response of Escherichia coliQ33680263
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coliQ33825068
Ultraviolet mutagenesis and inducible DNA repair in Escherichia coliQ34072546
Structural analysis of the dnaA and dnaN genes of Escherichia coliQ34251117
DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesisQ34631905
Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.Q36176656
The dnaN gene codes for the beta subunit of DNA polymerase III holoenzyme of escherichia coliQ36366845
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coliQ36389606
Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coliQ37060983
Molecular analysis of the recF gene of Escherichia coliQ37560016
Differences in mutagenic and recombinational DNA repair in enterobacteriaQ37692069
Mutation induced by DNA damage: a many protein affairQ37892175
Mechanism of replication of ultraviolet-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli. Implications for SOS mutagenesisQ38350743
DNA polymerase III holoenzyme of Escherichia coliQ39532142
The SOS regulatory system of Escherichia coliQ40335741
Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet lightQ40850491
Total reconstitution of DNA polymerase III holoenzyme reveals dual accessory protein clamps.Q41241578
Mutagenic DNA repair in Escherichia coli. III. Requirement for a function of DNA polymerase III in ultraviolet-light mutagenesisQ43893553
Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coliQ44028259
Dynamics of termination during in vitro replication of ultraviolet-irradiated DNA with DNA polymerase III holoenzyme of Escherichia coliQ44432656
The role of exonucleolytic processing and polymerase-DNA association in bypass of lesions during replication in vitro. Significance for SOS-targeted mutagenesis.Q45900677
DNA polymerase III holoenzyme of Escherichia coli. III. Distinctive processive polymerases reconstituted from purified subunits.Q45965353
DNA Polymerase III holoenzyme of Escherichia coli. IV. The holoenzyme is an asymmetric dimer with twin active sitesQ46648213
Mutagenic DNA repair in Escherichia coli. XVIII. Involvement of DNA polymerase III alpha-subunit (DnaE protein) in mutagenesis after exposure to UV light.Q54335591
Holoenzyme DNA polymerase III fixes mutations.Q54715229
The beta subunit modulates bypass and termination at UV lesions during in vitro replication with DNA polymerase III holoenzyme of Escherichia coli.Q54727372
The polymerase subunit of DNA polymerase III of Escherichia coli. II. Purification of the alpha subunit, devoid of nuclease activities.Q54791632
Involvement of DNA polymerase III in UV-induced mutagenesis of bacteriophage lambdaQ56944781
Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistanceQ59059568
Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coliQ67286950
The beta subunit dissociates readily from the Escherichia coli DNA polymerase III holoenzymeQ68929090
Different efficiency of UmuDC and MucAB proteins in UV light induced mutagenesis in Escherichia coliQ70162648
Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzymeQ70275596
P433issue8
P921main subjectEscherichia coliQ25419
P304page(s)2517-2524
P577publication date1992-04-01
P1433published inJournal of BacteriologyQ478419
P1476titleOverproduction of the beta subunit of DNA polymerase III holoenzyme reduces UV mutagenesis in Escherichia coli
P478volume174

Reverse relations

cites work (P2860)
Q35967829A monocysteine approach for probing the structure and interactions of the UmuD protein
Q48047346A small, stable RNA induced by oxidative stress: role as a pleiotropic regulator and antimutator
Q71265026Analysis of the mutagenic properties of the UmuDC, MucAB and RumAB proteins, using a site-specific abasic lesion
Q35618214Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach
Q73853915Anti-mutagenic activity of DNA damage-binding proteins mediated by direct inhibition of translesion replication
Q54601733Deamination of cytosine-containing pyrimidine photodimers in UV-irradiated DNA. Significance for UV light mutagenesis.
Q33594697Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function
Q33991270Inhibition of homologous recombination by the plasmid MucA'B complex
Q35968216Isolation and characterization of novel plasmid-encoded umuC mutants
Q36135582Levels of epsilon, an essential replication subunit of Escherichia coli DNA polymerase III, are controlled by heat shock proteins
Q24631110Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination
Q34603875Mutagenesis and more: umuDC and the Escherichia coli SOS response
Q36179739Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta
Q56903200Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta
Q29619755Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda
Q40810156Replication of damaged DNA and the molecular mechanism of ultraviolet light mutagenesis
Q40797739SOS mutagenesis
Q35606437Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis
Q36729830The beta subunit sliding DNA clamp is responsible for unassisted mutagenic translesion replication by DNA polymerase III holoenzyme
Q44192202The two-step model for translesion synthesis: then and now.

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