| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2013PLoSO...858233S |
| P356 | DOI | 10.1371/JOURNAL.PONE.0058233 |
| P932 | PMC publication ID | 3589264 |
| P698 | PubMed publication ID | 23472163 |
| P5875 | ResearchGate publication ID | 235886446 |
| P50 | author | Erica T Goddard | Q59702841 |
| Miles C Smith | Q84489059 | ||
| P2093 | author name string | David J Davido | |
| Mirna Perusina Lanfranca | |||
| P2860 | cites work | Oncogene-Induced Senescence: Putting the Brakes on Tumor Development | Q22065360 |
| Crimean-Congo hemorrhagic fever virus infection is lethal for adult type I interferon receptor-knockout mice | Q24276409 | ||
| Functional role of type I and type II interferons in antiviral defense | Q24276429 | ||
| Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene | Q24300102 | ||
| Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer. | Q53385647 | ||
| Decreased interferon sensitivity and production in cells transformed by SV40 and other oncogenic agents | Q68601100 | ||
| Real-time quantitative telomeric repeat amplification protocol assay for the detection of telomerase activity | Q73586375 | ||
| Cytochemical detection of a senescence-associated beta-galactosidase in endothelial and smooth muscle cells from human and rabbit blood vessels | Q74690451 | ||
| Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton. | Q38517737 | ||
| Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription | Q39646325 | ||
| Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication | Q39682468 | ||
| Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection | Q39748053 | ||
| The SV40 T antigen modulates CBP histone acetyltransferase activity | Q39778001 | ||
| A novel translational regulation function for the simian virus 40 large-T antigen gene | Q39868659 | ||
| Heterogeneity of the sensitivity of vesicular stomatitis virus to interferons | Q40099376 | ||
| A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1 | Q40106141 | ||
| Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells. | Q40267817 | ||
| Role of IFI 16 in cellular senescence of human fibroblasts | Q40543128 | ||
| Clonal variation in phenotype and life span of human embryonic fibroblasts (MRC-5) transduced with the catalytic component of telomerase (hTERT). | Q40791550 | ||
| Human telomerase reverse transcriptase-immortalized MRC-5 and HCA2 human fibroblasts are fully permissive for human cytomegalovirus | Q40820097 | ||
| Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide | Q40845313 | ||
| Absence of cancer-associated changes in human fibroblasts immortalized with telomerase | Q40978424 | ||
| Replicative senescence: implications for in vivo aging and tumor suppression | Q41003046 | ||
| Telomerase activation by the E6 gene product of human papillomavirus type 16. | Q41218028 | ||
| Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen | Q41272620 | ||
| The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen | Q41517399 | ||
| Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. | Q41563742 | ||
| p53 and hTERT determine sensitivity to viral apoptosis | Q41846932 | ||
| Human cytomegalovirus immediate-early 2 gene expression blocks virus-induced beta interferon production | Q41886260 | ||
| Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. | Q44488215 | ||
| Local type I IFN receptor signaling protects against virus spread within the central nervous system | Q45386700 | ||
| RELATIONSHIP BETWEEN THE ENVELOPE AND THE INFECTIVITY OF HERPES SIMPLEX VIRUS. | Q45714924 | ||
| 49 Virus plaque-reduction assay for interferon: Microplaque and regular macroplaque reduction assays | Q45805349 | ||
| Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization | Q45817912 | ||
| hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | Q24310670 | ||
| Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity | Q24599944 | ||
| Innate cellular response to virus particle entry requires IRF3 but not virus replication | Q24607212 | ||
| Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling | Q24658040 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| How cells respond to interferons | Q27861006 | ||
| THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS | Q28202269 | ||
| Viruses and interferon: a fight for supremacy | Q28220397 | ||
| HSV-1 ICP0: paving the way for viral replication | Q28243426 | ||
| HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes | Q28254780 | ||
| SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation | Q28282761 | ||
| The RNA component of human telomerase | Q28288330 | ||
| A method to identify cDNAs based on localization of green fluorescent protein fusion products | Q28510457 | ||
| Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3 | Q28743826 | ||
| Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
| Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures | Q29615028 | ||
| Cellular senescence: when bad things happen to good cells | Q29615561 | ||
| Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease | Q29615967 | ||
| The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth | Q33292242 | ||
| The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. | Q33292571 | ||
| Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responses | Q33573566 | ||
| Telomeres: protecting chromosomes against genome instability | Q33740892 | ||
| A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses | Q33771205 | ||
| Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts | Q33787378 | ||
| Herpes simplex virus ICP0 mutants are hypersensitive to interferon | Q33798242 | ||
| Herpes simplex virus triggers and then disarms a host antiviral response | Q33835458 | ||
| E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis | Q33852843 | ||
| The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. | Q33941037 | ||
| Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression | Q34014610 | ||
| Enumeration of the simian virus 40 early region elements necessary for human cell transformation | Q34117528 | ||
| Induction of interferon-stimulated genes by Simian virus 40 T antigens | Q34127232 | ||
| Adenovirus-5 E1A: paradox and paradigm | Q34131278 | ||
| Cellular transformation by SV40 large T antigen: interaction with host proteins | Q34177960 | ||
| Oncolytic viruses and cancer therapy | Q34234147 | ||
| Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7. | Q34368179 | ||
| Cellular senescence as a tumor-suppressor mechanism | Q34421790 | ||
| The ISG56/IFIT1 gene family | Q34492459 | ||
| Loss of the type I interferon pathway increases vulnerability of mice to genital herpes simplex virus 2 infection | Q34529742 | ||
| VSV-tumor selective replication and protein translation | Q34651274 | ||
| Recognition and elongation of telomeres by telomerase | Q34676361 | ||
| Senescence and epigenetic dysregulation in cancer | Q34801751 | ||
| ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency | Q35013167 | ||
| The multifunctional role of E1A in the transcriptional regulation of CREB/CBP-dependent target genes | Q35127678 | ||
| CK2 inhibitors increase the sensitivity of HSV-1 to interferon-β. | Q35175764 | ||
| Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes | Q35363520 | ||
| Reversal of human cellular senescence: roles of the p53 and p16 pathways | Q35561999 | ||
| The UniProt-GO Annotation database in 2011. | Q35630729 | ||
| Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors | Q35844406 | ||
| Efficient nuclear localization and immortalizing ability, two functions dependent on the adenovirus type 5 (Ad5) E1A second exon, are necessary for cotransformation with Ad5 E1B but not with T24ras | Q35852705 | ||
| The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27 | Q35886888 | ||
| Epigenetic changes in virus-associated human cancers. | Q36109306 | ||
| Quantitative telomeric overhang determination using a double-strand specific nuclease | Q36457105 | ||
| Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization | Q36754020 | ||
| Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18. | Q36800223 | ||
| Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA. | Q36831483 | ||
| How telomeres are replicated | Q36948200 | ||
| Relative sensitivities of viruses to different species of interferon | Q37135472 | ||
| Defining the molecular mechanisms of human cell immortalization | Q37173111 | ||
| Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression | Q37209049 | ||
| ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells | Q37321177 | ||
| Cell-type specific regulation of gene expression by simian virus 40 T antigens | Q37332894 | ||
| Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus | Q37490464 | ||
| Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response | Q37582942 | ||
| Phosphorylation site mutations affect herpes simplex virus type 1 ICP0 function | Q37743081 | ||
| The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein | Q38361692 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e58233 | |
| P577 | publication date | 2013-03-05 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | hTERT extends the life of human fibroblasts without compromising type I interferon signaling | |
| P478 | volume | 8 |
| Q38924032 | Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1. |
| Q35822653 | Development of a novel cell-based assay to monitor the transactivation activity of the HSV-1 protein ICP0. |
| Q47269135 | Emerging Alphaviruses are Sensitive to Cellular States Induced by a Novel Small Molecule Agonist of the STING Pathway |
| Q36655243 | Establishment and Characterization of a Telomerase-Immortalized Sheep Trophoblast Cell Line |
| Q38789307 | Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response |
| Q40705574 | SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1. |
| Q38751363 | Stimulation of the Replication of ICP0-Null Mutant Herpes Simplex Virus 1 and pp71-Deficient Human Cytomegalovirus by Epstein-Barr Virus Tegument Protein BNRF1. |
| Q28079490 | The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions |
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