Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis

scientific article

Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

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P356DOI10.1136/ANNRHEUMDIS-2012-203116
P698PubMed publication ID23599436
P5875ResearchGate publication ID236228518

P50authorLoreto CarmonaQ56419499
José Ramón ManeiroQ57029476
P2093author name stringJuan J Gomez-Reino
Eva Salgado
P2860cites workMasitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KITQ21142738
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An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid ArthritisQ28294375
Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavirQ28477930
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Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk.Q33382517
KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinaseQ33390326
Co-administration of the JAK inhibitor CP-690,550 and methotrexate is well tolerated in patients with rheumatoid arthritis without need for dose adjustmentQ33668201
Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot studyQ34301521
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Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trialQ34906164
The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placeboQ34989826
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Kinase inhibitors: a new class of antirheumatic drugsQ36277831
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The riddle of the mast cell: kit(CD117)-ligand as the missing link?Q40388512
Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.Q40530140
A multitude of kinases--which are the best targets in treating rheumatoid arthritis?Q40840109
A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tractQ41021396
cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransferQ42844060
Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis.Q43048581
Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial resultsQ43223134
Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disordersQ43233025
Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics.Q45926675
Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis.Q45930884
Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies.Q46030933
Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapyQ46055998
An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: a three-month randomized, placebo-controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agentsQ46066669
Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritisQ46140186
Inhibition of p38: has the fat lady sung?Q46140191
Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trialQ46271720
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signalingQ46438489
A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene familyQ48366626
Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.Q54589616
Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?Q54665731
Tofacitinib or Adalimumab versus Placebo in Rheumatoid ArthritisQ58912330
???Q28295371
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmeta-analysisQ815382
systematic reviewQ1504425
rheumatoid arthritisQ187255
P304page(s)871-882
P577publication date2013-04-18
P1433published inAnnals of the Rheumatic DiseasesQ4767876
P1476titleSafety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis
P478volume73

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