scholarly article | Q13442814 |
P819 | ADS bibcode | 2014PLoSO...9k4837L |
P356 | DOI | 10.1371/JOURNAL.PONE.0114837 |
P932 | PMC publication ID | 4267731 |
P698 | PubMed publication ID | 25514808 |
P5875 | ResearchGate publication ID | 269679486 |
P50 | author | Teresa Iglesias | Q57038769 |
Pilar Sánchez-Gómez | Q58788702 | ||
P2093 | author name string | Miguel Calero | |
Olga Calero | |||
Natalia Martinez | |||
Jose M Rojas | |||
Natasha Zarich | |||
Silvia Hernandez | |||
Daniel Peña-Jimenez | |||
Andrea Perez-Rodriguez | |||
Berta Anta | |||
Carlota A Garcia-Dominguez | |||
Gonzalo Leon | |||
Jose L Oliva | |||
Judit Castro | |||
Lara M Dura | |||
Lucia Sanchez-Ruiloba | |||
Teresa Gragera | |||
P2860 | cites work | ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF | Q24304344 |
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans | Q24317576 | ||
A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity | Q24319503 | ||
soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling | Q24323124 | ||
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair | Q24336157 | ||
The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf | Q24607066 | ||
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases | Q24680631 | ||
Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1 | Q24685178 | ||
Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells | Q27303629 | ||
Functional Integration of the Conserved Domains of Shoc2 Scaffold | Q27315483 | ||
Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling. | Q50562257 | ||
Cognitive profile of disorders associated with dysregulation of the RAS/MAPK signaling cascade. | Q51942865 | ||
Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. | Q52177288 | ||
ras Genes and Human Cancer: Different Implications and Different Roles | Q57375823 | ||
PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity | Q67542908 | ||
Erbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complex | Q28282958 | ||
Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation | Q28505657 | ||
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate | Q28576088 | ||
Coordinating ERK/MAPK signalling through scaffolds and inhibitors | Q29618995 | ||
Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction | Q30157899 | ||
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. | Q30460881 | ||
Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway | Q33391576 | ||
Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein | Q33721174 | ||
Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. | Q33966221 | ||
Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms | Q34168435 | ||
An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth | Q34383929 | ||
Signaling pathways for PC12 cell differentiation: making the right connections | Q34662640 | ||
Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics | Q34761596 | ||
The leucine-rich repeat structure. | Q34769694 | ||
Scaffolds: interaction platforms for cellular signalling circuits. | Q34774526 | ||
Targeting the mitogen-activated protein kinase cascade to treat cancer | Q35968411 | ||
SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor | Q36451902 | ||
A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions | Q36684518 | ||
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation | Q36733429 | ||
Scaffold proteins of MAP-kinase modules. | Q36819386 | ||
MAP kinases and the control of nuclear events | Q36819401 | ||
Protein scaffolds in MAP kinase signalling | Q37156628 | ||
Scaffold proteins and immune-cell signalling | Q37357014 | ||
The ERK Cascade: Distinct Functions within Various Subcellular Organelles | Q37903694 | ||
Grasping objects: the cortical mechanisms of visuomotor transformation | Q38463051 | ||
Sur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling. | Q38472620 | ||
Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development. | Q39692868 | ||
The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf. | Q39763725 | ||
Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2 | Q40401260 | ||
p75 and Trk: a two-receptor system | Q40419805 | ||
Critical contribution of linker proteins to Raf kinase activation | Q40763817 | ||
Palmitoylation of ERBIN is required for its plasma membrane localization | Q42812704 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | neurite | Q1534415 |
P304 | page(s) | e114837 | |
P577 | publication date | 2014-12-16 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Shoc2/Sur8 protein regulates neurite outgrowth | |
P478 | volume | 9 |
Q38755297 | SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling | cites work | P2860 |