Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

scientific article

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair is …
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scholarly articleQ13442814

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P819ADS bibcode1998PNAS...95.9997G
P356DOI10.1073/PNAS.95.17.9997
P932PMC publication ID21450
P698PubMed publication ID9707589
P5875ResearchGate publication ID13576902

P2093author name stringL D Samson
L M Posnick
B J Glassner
L J Rasmussen
M T Najarian
P2860cites workMutations of Bacteria from Virus Sensitivity to Virus ResistanceQ24533278
Rates of spontaneous mutationQ24548000
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylaseQ24562354
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoterQ27860697
Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IVQ27930192
DNA repair in eukaryotesQ41114782
Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defectsQ41140973
The role of DNA repair in the prevention of cancerQ41193565
Developmental control of cell cycle regulators: a fly's perspectiveQ41239581
DNA repair functions in heterologous cellsQ41311787
DNA glycosylases in the base excision repair of DNAQ41532551
What structural features determine repair enzyme specificity and mechanism in chemically modified DNA?Q41557025
The origin of spontaneous mutation in Saccharomyces cerevisiae.Q41616101
Specificity of the yeast rev3 delta antimutator and REV3 dependency of the mutator resulting from a defect (rad1 delta) in nucleotide excision repair.Q41764425
Dominant mutators in Escherichia coliQ42036991
Ultraviolet mutagenesis studies of [psi], a cytoplasmic determinant of Saccharomyces cerevisiaeQ42059923
Spontaneous mutation by mutagenic repair of spontaneous lesions in DNAQ44981191
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
Mutational specificity of DNA precursor pool imbalances in yeast arising from deoxycytidylate deaminase deficiency or treatment with thymidylate.Q52481551
Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae.Q54175192
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repairQ64389285
Yeast DNA 3'-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kineticsQ70226815
Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12Q70362317
Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repairQ71666033
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiaeQ72240900
Deoxycytidyl transferase activity of yeast REV1 proteinQ27931173
The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replicationQ27933493
Mutants of yeast defective in mutation induced by ultraviolet lightQ27935336
Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coliQ27937308
Thymine-thymine dimer bypass by yeast DNA polymerase zetaQ27938043
Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damageQ27939022
5-Fluoroorotic acid as a selective agent in yeast molecular geneticsQ28131614
A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strainsQ28131619
Mutations predisposing to hereditary nonpolyposis colorectal cancerQ28235642
Pathway correcting DNA replication errors in Saccharomyces cerevisiaeQ28263175
The clonal evolution of tumor cell populationsQ28271546
Mutagenesis by apurinic/apyrimidinic sitesQ28300337
Amplified expression of the tag+ and alkA+ genes in Escherichia coli: identification of gene products and effects on alkylation resistanceQ28493053
Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNAQ28610592
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylasesQ28610597
Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiaeQ29547797
Conditional Mutator Gene in Escherichia coli : Isolation, Mapping, and Effector StudiesQ33792520
Release of normal bases from intact DNA by a native DNA repair enzymeQ33888049
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replicationQ34257072
A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzymeQ34258669
Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonucleaseQ35686019
The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicityQ35979427
In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cellsQ36155707
Endonuclease IV (nfo) mutant of Escherichia coliQ36261707
Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylaseQ36560558
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.Q36568353
Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylaseQ36730360
A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiaeQ36826695
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae.Q37064006
The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions?Q37713424
Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12Q39938870
Mutagenesis in Saccharomyces cerevisiae.Q40324911
Mismatch repair and cancer susceptibilityQ40535755
Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coliQ40566046
Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutationQ40640344
The RAD6 DNA repair pathway in Saccharomyces cerevisiae: what does it do, and how does it do it?Q40671595
The base excision repair pathwayQ40930021
Chapter 1 Measuring Spontaneous Mutation Rates in YeastQ40936432
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
P304page(s)9997-10002
P577publication date1998-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleGeneration of a strong mutator phenotype in yeast by imbalanced base excision repair
P478volume95

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