scholarly article | Q13442814 |
P819 | ADS bibcode | 1998PNAS...95.9997G |
P356 | DOI | 10.1073/PNAS.95.17.9997 |
P932 | PMC publication ID | 21450 |
P698 | PubMed publication ID | 9707589 |
P5875 | ResearchGate publication ID | 13576902 |
P2093 | author name string | L D Samson | |
L M Posnick | |||
B J Glassner | |||
L J Rasmussen | |||
M T Najarian | |||
P2860 | cites work | Mutations of Bacteria from Virus Sensitivity to Virus Resistance | Q24533278 |
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Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase | Q24562354 | ||
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter | Q27860697 | ||
Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV | Q27930192 | ||
DNA repair in eukaryotes | Q41114782 | ||
Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects | Q41140973 | ||
The role of DNA repair in the prevention of cancer | Q41193565 | ||
Developmental control of cell cycle regulators: a fly's perspective | Q41239581 | ||
DNA repair functions in heterologous cells | Q41311787 | ||
DNA glycosylases in the base excision repair of DNA | Q41532551 | ||
What structural features determine repair enzyme specificity and mechanism in chemically modified DNA? | Q41557025 | ||
The origin of spontaneous mutation in Saccharomyces cerevisiae. | Q41616101 | ||
Specificity of the yeast rev3 delta antimutator and REV3 dependency of the mutator resulting from a defect (rad1 delta) in nucleotide excision repair. | Q41764425 | ||
Dominant mutators in Escherichia coli | Q42036991 | ||
Ultraviolet mutagenesis studies of [psi], a cytoplasmic determinant of Saccharomyces cerevisiae | Q42059923 | ||
Spontaneous mutation by mutagenic repair of spontaneous lesions in DNA | Q44981191 | ||
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair | Q46617407 | ||
Mutational specificity of DNA precursor pool imbalances in yeast arising from deoxycytidylate deaminase deficiency or treatment with thymidylate. | Q52481551 | ||
Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae. | Q54175192 | ||
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair | Q64389285 | ||
Yeast DNA 3'-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics | Q70226815 | ||
Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12 | Q70362317 | ||
Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair | Q71666033 | ||
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae | Q72240900 | ||
Deoxycytidyl transferase activity of yeast REV1 protein | Q27931173 | ||
The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication | Q27933493 | ||
Mutants of yeast defective in mutation induced by ultraviolet light | Q27935336 | ||
Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli | Q27937308 | ||
Thymine-thymine dimer bypass by yeast DNA polymerase zeta | Q27938043 | ||
Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage | Q27939022 | ||
5-Fluoroorotic acid as a selective agent in yeast molecular genetics | Q28131614 | ||
A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains | Q28131619 | ||
Mutations predisposing to hereditary nonpolyposis colorectal cancer | Q28235642 | ||
Pathway correcting DNA replication errors in Saccharomyces cerevisiae | Q28263175 | ||
The clonal evolution of tumor cell populations | Q28271546 | ||
Mutagenesis by apurinic/apyrimidinic sites | Q28300337 | ||
Amplified expression of the tag+ and alkA+ genes in Escherichia coli: identification of gene products and effects on alkylation resistance | Q28493053 | ||
Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA | Q28610592 | ||
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases | Q28610597 | ||
Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae | Q29547797 | ||
Conditional Mutator Gene in Escherichia coli : Isolation, Mapping, and Effector Studies | Q33792520 | ||
Release of normal bases from intact DNA by a native DNA repair enzyme | Q33888049 | ||
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication | Q34257072 | ||
A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme | Q34258669 | ||
Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease | Q35686019 | ||
The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity | Q35979427 | ||
In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells | Q36155707 | ||
Endonuclease IV (nfo) mutant of Escherichia coli | Q36261707 | ||
Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase | Q36560558 | ||
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. | Q36568353 | ||
Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase | Q36730360 | ||
A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae | Q36826695 | ||
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. | Q37064006 | ||
The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? | Q37713424 | ||
Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12 | Q39938870 | ||
Mutagenesis in Saccharomyces cerevisiae. | Q40324911 | ||
Mismatch repair and cancer susceptibility | Q40535755 | ||
Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coli | Q40566046 | ||
Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation | Q40640344 | ||
The RAD6 DNA repair pathway in Saccharomyces cerevisiae: what does it do, and how does it do it? | Q40671595 | ||
The base excision repair pathway | Q40930021 | ||
Chapter 1 Measuring Spontaneous Mutation Rates in Yeast | Q40936432 | ||
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phenotype | Q104053 |
P304 | page(s) | 9997-10002 | |
P577 | publication date | 1998-08-01 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Generation of a strong mutator phenotype in yeast by imbalanced base excision repair | |
P478 | volume | 95 |
Q28179629 | A fission yeast homologue of the human uracil-DNA-glycosylase and their roles in causing DNA damage after overexpression |
Q33886881 | A method for detecting abasic sites in living cells: age-dependent changes in base excision repair |
Q35040027 | A novel function of DNA polymerase zeta regulated by PCNA. |
Q37052491 | Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice |
Q28143939 | Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means |
Q34657817 | Accumulation of abasic sites induces genomic instability in normal human gastric epithelial cells during Helicobacter pylori infection |
Q44152741 | Active-site clashes prevent the human 3-methyladenine DNA glycosylase from improperly removing bases |
Q31149297 | Adaptive swarm cluster-based dynamic multi-objective synthetic minority oversampling technique algorithm for tackling binary imbalanced datasets in biomedical data classification. |
Q33384119 | Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. |
Q36651488 | Balancing repair and tolerance of DNA damage caused by alkylating agents |
Q27025537 | Base excision repair and cancer |
Q34586254 | Base excision repair capacity in informing healthspan |
Q40039599 | Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome |
Q34283911 | Base excision repair in a network of defence and tolerance |
Q33984258 | Base excision repair in yeast and mammals |
Q34374847 | Base excision repair. |
Q35838174 | Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function |
Q35978838 | Cellular functions of DNA polymerase zeta and Rev1 protein |
Q35037431 | Cellular roles of DNA polymerase zeta and Rev1 protein |
Q36565849 | Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair |
Q58097213 | Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome |
Q35132594 | Complex transcriptional responses to macromolecular damaging agents: regulatory responses specific for SN2 alkylation and the MAG1 gene |
Q36759955 | Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents |
Q27765744 | Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision |
Q45231153 | Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver |
Q44954472 | DNA binding and nucleotide flipping by the human DNA repair protein AGT. |
Q33984301 | DNA damage-induced mutation: tolerance via translesion synthesis |
Q28709604 | DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae |
Q43819410 | Deletion of the MAG1 DNA glycosylase gene suppresses alkylation-induced killing and mutagenesis in yeast cells lacking AP endonucleases |
Q46797440 | Deregulation of homologous recombination DNA repair in alkylating agent-treated stem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia |
Q33921147 | Differential control of dNTP biosynthesis and genome integrity maintenance by the dUTPase superfamily enzymes |
Q28392669 | Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase |
Q39425329 | Elevated oxidative stress and DNA damage and repair levels in urinary bladder carcinomas associated with schistosomiasis |
Q35003614 | Enzymatic MPG DNA repair assays for two different oxidative DNA lesions reveal associations with increased lung cancer risk |
Q43831017 | Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene |
Q39687136 | Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis |
Q33951115 | Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase. |
Q35869772 | Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics |
Q34372632 | Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi |
Q33490616 | Gastrointestinal hyperplasia with altered expression of DNA polymerase beta |
Q38310342 | Gelonin is an unusual DNA glycosylase that removes adenine from single-stranded DNA, normal base pairs and mismatches |
Q46329424 | Genome-wide map of Apn1 binding sites under oxidative stress in Saccharomyces cerevisiae. |
Q37247774 | Going ape as an approach to cancer therapeutics |
Q36814155 | Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM. |
Q34055705 | Human base excision repair creates a bias toward -1 frameshift mutations |
Q37700926 | Imbalanced adaptive responses associated with microsatellite instability in cholangiocarcinoma |
Q33993117 | Imbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli |
Q48137958 | Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure |
Q34380700 | Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase |
Q44013207 | Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent. |
Q34332668 | Interplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation system |
Q28507940 | Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage |
Q44267635 | Kinetics and binding of the thymine-DNA mismatch glycosylase, Mig-Mth, with mismatch-containing DNA substrates |
Q44292685 | Marathon running alters the DNA base excision repair in human skeletal muscle. |
Q28510960 | Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein |
Q36319705 | Mechanisms of glycosylase induced genomic instability |
Q36686012 | Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks |
Q77363798 | Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase |
Q24669704 | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG |
Q37861732 | Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools |
Q33770262 | Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p |
Q34201783 | Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA |
Q36411751 | N-methylpurine DNA glycosylase and OGG1 DNA repair activities: opposite associations with lung cancer risk |
Q39632856 | N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage |
Q89179271 | Nitric oxide induced S-nitrosation causes base excision repair imbalance |
Q33888666 | Overexpression of enzymes that repair endogenous damage to DNA. |
Q52727657 | Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer. |
Q39445271 | Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae |
Q33628462 | Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae |
Q38476459 | Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae. |
Q52730088 | Programming of Cell Resistance to Genotoxic and Oxidative Stress. |
Q47587670 | Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene |
Q73404201 | REV3 is required for spontaneous but not methylation damage-induced mutagenesis of Saccharomyces cerevisiae cells lacking O6-methylguanine DNA methyltransferase |
Q32063493 | Recent progress in the biology, chemistry and structural biology of DNA glycosylases |
Q36496110 | Repair of Alkylation Damage in Eukaryotic Chromatin Depends on Searching Ability of Alkyladenine DNA Glycosylase |
Q36533084 | Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. |
Q37507628 | Rev1 is a base excision repair enzyme with 5'-deoxyribose phosphate lyase activity. |
Q42012937 | Role of DNA base excision repair in the mutability and virulence of Streptococcus mutans |
Q36610269 | Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans |
Q27675515 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2 |
Q43511185 | Sequence variation in the human uracil-DNA glycosylase (UNG) gene |
Q36855094 | Single-molecule DNA repair in live bacteria. |
Q45248977 | Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. |
Q33947885 | Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase |
Q34687289 | Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase |
Q33360502 | Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival |
Q27937334 | Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag) |
Q47417619 | Targeted mutagenesis: A sniper-like diversity generator in microbial engineering |
Q38341656 | The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site |
Q26801375 | The Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human Cancer |
Q44267647 | The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination. |
Q37294813 | The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products |
Q34265917 | The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. |
Q35656781 | The amino-terminal tails of histones H2A and H3 coordinate efficient base excision repair, DNA damage signaling and postreplication repair in Saccharomyces cerevisiae |
Q37302944 | The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis |
Q30043983 | The role of DNA mismatch repair in generating genetic diversity and drug resistance in malaria parasites |
Q27938847 | Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. |
Q35609296 | Tumbling down a different pathway to genetic instability. |
Q27940072 | Uracil-DNA glycosylase-deficient yeast exhibit a mitochondrial mutator phenotype |
Q35004482 | Variation in base excision repair capacity |
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