Pharmacotherapy of addictions

scientific article

Pharmacotherapy of addictions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/NRD897
P698PubMed publication ID12209151
P5875ResearchGate publication ID11180100

P50authorMary Jeanne KreekQ21531361
P2093author name stringK Steven LaForge
Eduardo Butelman
P2860cites workAddiction and the brain: The neurobiology of compulsion and its persistenceQ22337278
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addictionQ24320057
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preferenceQ24603526
Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout miceQ24650110
Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonistQ28141108
The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative painQ28146053
U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of ratsQ28236902
Psychotomimesis mediated by kappa opiate receptorsQ28287612
Cyclazocine revisitedQ28298711
Cocaine abuse sharply reduced in an effective methadone maintenance programQ28368155
Laboratory measures of methylphenidate effects in cocaine-dependent patients receiving treatmentQ28369446
Disulfiram treatment for cocaine dependence in methadone-maintained opioid addictsQ28373528
Effects of chronic 'Binge' cocaine administration on plasma ACTH and corticosterone levels in mice deficient in DARPP-32Q28373956
Dopamine D2/D3 receptors modulate cocaine's reinforcing and discriminative stimulus effects in rhesus monkeysQ28374214
Effect of a selective dopamine D1 agonist (ABT-431) on smoked cocaine self-administration in humansQ28374715
GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamineQ28583003
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesiaQ28585437
Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptorsQ28592400
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving ratsQ29619737
Cocaine receptors on dopamine transporters are related to self-administration of cocaineQ29619876
Molecular basis of long-term plasticity underlying addictionQ29620539
Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trialQ31397850
The economic costs of heroin addiction in the United StatesQ31799483
Depot naltrexone: long-lasting antagonism of the effects of heroin in humansQ33837599
A double-blind, placebo-controlled study of oral nalmefene for alcohol dependenceQ33844871
Cocaine self-administration in dopamine-transporter knockout miceQ33858028
Reinforcing and discriminative stimulus effects of RTI 111, a 3-phenyltropane analog, in rhesus monkeys: interaction with methamphetamineQ33938662
Modulation of cocaine and food self-administration by low- and high-efficacy D1 agonists in squirrel monkeysQ33955144
Effects of chronic administration of the D1 receptor partial agonist SKF 77434 on cocaine self-administration in rhesus monkeysQ33958139
RTI 113, a 3-phenyltropane analog, produces long-lasting cocaine-like discriminative stimulus effects in rats and squirrel monkeysQ33959235
A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependenceQ34059254
Effects of ecopipam, a selective dopamine D1 antagonist, on smoked cocaine self-administration by humansQ34083204
Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeysQ34105371
Opioid receptor and peptide gene polymorphisms: potential implications for addictionsQ34116565
Narcotic blockadeQ34203445
The kappa-opioid receptor agonist U-69593 attenuates cocaine-induced behavioral sensitization in the rat.Q44340372
Binaltorphimine-related bivalent ligands and their kappa opioid receptor antagonist selectivityQ44342764
Increased mu opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine cravingQ44343960
Prodynorphin, proenkephalin and kappa opioid receptor mRNA responses to acute "binge" cocaineQ44344981
Hypothalamic-pituitary-adrenal axis hypersensitivity to naloxone in opioid dependence: a case of naloxone-induced withdrawalQ44344989
Mu opioid receptor phosphorylation, desensitization, and ligand efficacyQ44347204
Mu opioid receptor gene variants: lack of association with alcohol dependenceQ44347504
Kappa-opioid receptor blockade with nor-binaltorphimine modulates cocaine self-administration in drug-naive ratsQ44350622
Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brainQ44351656
Acute "binge" cocaine increases mu-opioid receptor mRNA levels in areas of the rat mesolimbic mesocortical dopamine systemQ44351828
Beta endorphin levels during heroin, methadone, buprenorphine, and naloxone challenges: preliminary findingsQ44931718
Desipramine treatment of cocaine dependence in methadone-maintained patientsQ45110517
Auditory deprivation modifies sleep in the guinea-pigQ46321403
3-4-Methylenedioxymethamphetamine-induced acute changes in dopamine transporter functionQ47816087
Medical Safety and Side Effects of Methadone in Tolerant IndividualsQ47961561
‘Binge’ cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamenQ48229797
Cocaine self-administration increases preprodynorphin, but not c-fos, mRNA in rat striatum.Q48298508
Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholismQ48359259
Cocaine self-administration differentially alters mRNA expression of striatal peptidesQ48521156
Opioids excite dopamine neurons by hyperpolarization of local interneuronsQ48543154
Behavioral stereotypies induced by "binge' cocaine administration are independent of drug-induced increases in corticosterone levelsQ48680422
Imipramine treatment of cocaine abuse: possible boundaries of efficacyQ48794595
Neural substrates of opiate reinforcementQ48840037
Steady-state methadone in rats does not change mRNA levels of corticotropin-releasing factor, its pituitary receptor or proopiomelanocortinQ48863649
Metyrapone-induced withdrawal symptomsQ48907448
Acute subjective effects of dynorphin A(1-13) infusion in normal healthy subjects.Q51091137
Effect of dopamine receptor antagonists on cocaine subjective effects: a naturalistic case study.Q51103486
Effects of intravenous cocaine are partially attenuated by haloperidol.Q51180759
Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans.Q51467625
Baclofen as a cocaine anti-craving medication: a preliminary clinical study.Q51526312
Baclofen attenuates the reinforcing effects of cocaine in rats.Q51561412
Double-blind comparison of bromocriptine and placebo in cocaine withdrawal.Q51611582
Treatment of Cocaine Dependence in Methadone Maintenance Clients: A Pilot Study Comparing the Efficacy of Desipramine and AmantadineQ51701097
Reliability of sequential naloxone challenge tests.Q52012693
The effects of psychosocial services in substance abuse treatment.Q52273370
Hypothalamic-pituitary-adrenal activity and pro-opiomelanocortin mRNA levels in the hypothalamus and pituitary of the rat are differentially modulated by acute intermittent morphine with or without water restriction stress.Q52277626
Pergolide mesylate for cocaine abuse: a controlled preliminary trial.Q53930571
Naltrexone and coping skills therapy for alcohol dependence. A controlled studyQ67587951
A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addictsQ69997055
Circadian rhythms and levels of beta-endorphin, ACTH, and cortisol during chronic methadone maintenance treatment in humansQ70186821
The treatment of alcoholism in FranceQ70910544
Comparison of acamprosate and placebo in long-term treatment of alcohol dependenceQ71177254
Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependenceQ71226356
ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humansQ72413578
Effects of E-2078, a stable dynorphin A(1-8) analog, on sedation and serum prolactin levels in rhesus monkeysQ73257779
Naltrexone and alcohol dependence. Role of subject complianceQ73665563
Naltrexone in the treatment of alcohol dependenceQ34241680
A MEDICAL TREATMENT FOR DIACETYLMORPHINE (HEROIN) ADDICTION. A CLINICAL TRIAL WITH METHADONE HYDROCHLORIDE.Q34260580
Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity studyQ34307279
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors.Q34310825
Cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbensQ34420279
Behavioral neurobiology of alcohol addiction: recent advances and challenges.Q34616149
Nicotine addiction: insights from recent animal studiesQ34732274
The effects of spiradoline (U-62066E), a kappa-opioid receptor agonist, on neuroendocrine function in manQ35025817
Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathwayQ36877274
One-year follow-up of disulfiram and psychotherapy for cocaine-alcohol users: sustained effects of treatmentQ39550515
Behavioral methods for the assessment of alcohol tolerance and dependenceQ39707921
Medical complications in methadone patientsQ39787522
An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expressionQ40904223
A multicenter trial of bupropion for cocaine dependence in methadone-maintained patientsQ40963918
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor geneQ41157124
Opioid receptors: some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseasesQ41247930
Opiate and Cocaine Addictions: Challenge for PharmacotherapiesQ41527887
High-dose naloxone infusions in normals. Dose-dependent behavioral, hormonal, and physiological responsesQ41556109
Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in ratsQ41573401
Effects of cyclazocine on cocaine self-administration in ratsQ42538794
Disulfiram effects on acute cocaine administrationQ42538809
Methylphenidate treatment for cocaine abusers with adult attention-deficit/hyperactivity disorder: a pilot studyQ42540961
Drug dependence: stress and dysregulation of brain reward pathwaysQ43070756
Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addictionQ43562236
Crack cocaine--a two-year follow-up of treated patientsQ43564570
Effectiveness of propranolol for cocaine dependence treatment may depend on cocaine withdrawal symptom severityQ43571809
The frequency of cocaine administration impacts cocaine-induced receptor alterationsQ43590159
Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats.Q43629682
The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis studyQ43695146
Reinforcing effects of D2 dopamine receptor agonists and partial agonists in rhesus monkeysQ43728938
Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinanQ43759911
Hypothalamic CRH mRNA levels are differentially modulated by repeated 'binge' cocaine with or without D(1) dopamine receptor blockadeQ43764432
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.Q43770574
Effect of flupenthixol on subjective and cardiovascular responses to intravenous cocaine in humansQ43774548
Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer.Q43792467
The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockadeQ43829059
Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis.Q43893915
Cortisol levels during chronic naltrexone maintenance treatment in ex-opiate addictsQ43897314
Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbensQ43915028
Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient miceQ43937577
Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuseQ43981246
Hypothalamic-pituitary-adrenocortical (HPA) axis response and biotransformation of oral naltrexone: preliminary examination of relationship to family history of alcoholismQ43991017
Chronic cocaine alters brain mu opioid receptorsQ44331495
Morphine self-administration in mu-opioid receptor-deficient miceQ44332170
Kappa opioid inhibition of morphine and cocaine self-administration in ratsQ44333113
Treatment of opioid-induced constipation with oral naloxone: A pilot studyQ44333656
Association between mu opioid receptor gene polymorphisms and Chinese heroin addictsQ44335420
Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors.Q44335466
Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on kappa-opioid agonists in the mouse writhing assayQ44335990
P433issue9
P921main subjectpharmacotherapyQ701216
P304page(s)710-726
P577publication date2002-09-01
P1433published inNature Reviews Drug DiscoveryQ45998
P1476titlePharmacotherapy of addictions
P478volume1

Reverse relations

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