| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2003PNAS..100.3251Z |
| P356 | DOI | 10.1073/PNAS.2627983100 |
| P932 | PMC publication ID | 152278 |
| P698 | PubMed publication ID | 12626749 |
| P5875 | ResearchGate publication ID | 10864849 |
| P2093 | author name string | Hong Zhang | |
| Stanley N Cohen | |||
| Kuang-Hung Pan | |||
| P2860 | cites work | Microarray analysis of replicative senescence | Q41693910 |
| Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells | Q42818739 | ||
| Telomere position effect in human cells | Q43642023 | ||
| Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. | Q44816904 | ||
| Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes | Q46069224 | ||
| Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation | Q47801895 | ||
| Age-dependent modifications of gene expression in human fibroblasts | Q47804767 | ||
| Refining the telomere-telomerase hypothesis of aging and cancer | Q47960661 | ||
| Large clusters of co-expressed genes in the Drosophila genome | Q52111333 | ||
| p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells | Q53385483 | ||
| The cell biology of human aging / Leonard Hayflick. - (1976) | Q67839746 | ||
| Telomere positional effects and the regulation of cellular senescence | Q68007322 | ||
| Is beta-galactosidase staining a marker of senescence in vitro and in vivo? | Q73896683 | ||
| Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence | Q24297146 | ||
| Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
| Evidence for large domains of similarly expressed genes in the Drosophila genome | Q24530131 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| Significance analysis of microarrays applied to the ionizing radiation response | Q24606608 | ||
| Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase | Q27860668 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription | Q28131683 | ||
| Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans | Q28131824 | ||
| Senescence Induced by Altered Telomere State, Not Telomere Loss | Q28315731 | ||
| The serial cultivation of human diploid cell strains | Q29547356 | ||
| Switching and signaling at the telomere | Q29615653 | ||
| DNA arrays for analysis of gene expression | Q29617395 | ||
| The human transcriptome map: clustering of highly expressed genes in chromosomal domains | Q29622859 | ||
| A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression | Q30615496 | ||
| How might replicative senescence contribute to human ageing? | Q33536849 | ||
| Analysis of DNA microarrays using algorithms that employ rule-based expert knowledge | Q34012405 | ||
| Cellular senescence: mitotic clock or culture shock? | Q34019131 | ||
| Genes involved in senescence and immortalization | Q34076841 | ||
| Clustering of housekeeping genes provides a unified model of gene order in the human genome | Q34126902 | ||
| Cellular senescence as a tumor-protection mechanism: the essential role of counting | Q34132858 | ||
| Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans | Q34148035 | ||
| The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity | Q34687302 | ||
| Historical claims and current interpretations of replicative aging | Q34713128 | ||
| Senescence as a mode of tumor suppression | Q35034137 | ||
| Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions | Q35076939 | ||
| Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. | Q35217164 | ||
| Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent | Q36562455 | ||
| Telomere loss: mitotic clock or genetic time bomb? | Q36706939 | ||
| Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract | Q37565967 | ||
| Genetic analysis of cellular senescence. | Q40455381 | ||
| Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells | Q40751988 | ||
| Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening | Q40836730 | ||
| Replicative senescence: implications for in vivo aging and tumor suppression | Q41003046 | ||
| Replicative senescence: considerations relating to the stability of heterochromatin domains | Q41032557 | ||
| Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts | Q41053539 | ||
| The Pathway of Cell Senescence: WI-38 Cells Arrest in Late G1 and Are Unable to Traverse the Cell Cycle from a True G0 State | Q41064950 | ||
| Human papillomavirus type 16 E7 alleviates a proliferation block in early passage human mammary epithelial cells | Q41205227 | ||
| The heterochromatin loss model of aging | Q41604621 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3251-3256 | |
| P577 | publication date | 2003-03-07 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci | |
| P478 | volume | 100 |
| Q33532644 | A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen |
| Q47314793 | Activated p53 suppresses the histone methyltransferase EZH2 gene |
| Q83348681 | Age related changes of the extracellular matrix and stem cell maintenance |
| Q53606375 | Age- and cell cycle-dependent changes in EPC-1/PEDF promoter activity in human diploid fibroblast-like (HDF) cells |
| Q34507732 | Aging‐related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression |
| Q28237169 | An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma |
| Q33819277 | Analysis of Gene Expression in Human Dermal Fibroblasts Treated with Senescence-Modulating COX Inhibitors |
| Q35825021 | Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence |
| Q38040612 | Are aging biomarkers clinically relevant in oncogeriatrics? |
| Q37520495 | Calculating the statistical significance of physical clusters of co-regulated genes in the genome: the role of chromatin in domain-wide gene regulation. |
| Q36791575 | Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity |
| Q28081013 | Cellular and molecular biology of aging endothelial cells |
| Q35815320 | Cellular senescence and organismal aging |
| Q33953067 | Cellular senescence and protein degradation: breaking down cancer |
| Q38383224 | Cellular senescence: from growth arrest to immunogenic conversion |
| Q29615561 | Cellular senescence: when bad things happen to good cells |
| Q31096789 | Cloning and characterization of cellular senescence-associated genes in human fibroblasts by suppression subtractive hybridization |
| Q30952223 | Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing |
| Q30829491 | Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs |
| Q24804426 | Confirmation of human protein interaction data by human expression data |
| Q36007231 | Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq |
| Q37246647 | Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. |
| Q90571258 | Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells |
| Q46845463 | Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker |
| Q80196205 | Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions |
| Q47138550 | Dissecting cellular senescence and SASP in Drosophila |
| Q36608493 | Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo |
| Q40450417 | Early BrdU-responsive genes constitute a novel class of senescence-associated genes in human cells. |
| Q35915738 | Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cells |
| Q33852330 | Effects of threshold choice on biological conclusions reached during analysis of gene expression by DNA microarrays |
| Q37346914 | Enhanced control of proliferation in telomerized cells |
| Q53335869 | Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. |
| Q36614769 | Extracellular influences on tumour angiogenesis in the aged host |
| Q38857075 | Fusion with human lung cancer cells elongates the life span of human umbilical endothelial cells and enhances the anti-tumor immunity |
| Q57149243 | G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes |
| Q34423779 | G-NEST: a gene neighborhood scoring tool to identify co-conserved, co-expressed genes |
| Q39672451 | Gamma-Tocotrienol Modulated Gene Expression in Senescent Human Diploid Fibroblasts as Revealed by Microarray Analysis |
| Q40940632 | Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts. |
| Q36744909 | Genome-Wide Detection of Gene Coexpression Domains Showing Linkage to Regions Enriched with Polymorphic Retrotransposons in Recombinant Inbred Mouse Strains. |
| Q47999229 | Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence |
| Q28488081 | Genome-wide transcriptional reorganization associated with senescence-to-immortality switch during human hepatocellular carcinogenesis |
| Q40052404 | Genomic and nongenomic effects of estrogen signaling in human endometrial cells: involvement of the growth factor receptor signaling downstream AKT pathway |
| Q52926926 | Genomic organization of transcriptomes in mammals: Coregulation and cofunctionality |
| Q33317073 | Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines |
| Q36852086 | Global analysis of Escherichia coli RNA degradosome function using DNA microarrays |
| Q35784727 | Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence |
| Q39111369 | Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas |
| Q37138581 | Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape |
| Q37198572 | Living on a break: cellular senescence as a DNA-damage response |
| Q51593972 | Mapping development-related and age-related chromatin remodeling by a high throughput ChIP-HPLC approach |
| Q38072352 | Markers of Cellular Senescence |
| Q37436283 | Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells |
| Q40837123 | Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape. |
| Q55312849 | Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy. |
| Q33251346 | Non-random clustering of stress-related genes during evolution of the S. cerevisiae genome |
| Q26786557 | Noncoding RNA control of cellular senescence |
| Q36906576 | Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence |
| Q38235660 | Physiological and pathological consequences of cellular senescence. |
| Q36444277 | Premature senescence of endothelial cells: Methusaleh's dilemma |
| Q37390493 | Protein kinase CK2 regulates cytoskeletal reorganization during ionizing radiation-induced senescence of human mesenchymal stem cells |
| Q36126403 | RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. |
| Q39168515 | Radiation-induced cellular senescence results from a slippage of long-term G2arrested cells into G1phase |
| Q34665706 | Regulation of Senescence in Cancer and Aging |
| Q33336408 | Replicative senescence of mesenchymal stem cells: a continuous and organized process |
| Q39305388 | SASP regulation by noncoding RNA. |
| Q36906259 | Semantic Signature: Comparative Interpretation of Gene Expression on a Semantic Space. |
| Q82538433 | Senescence in cells in aseptic loosening after total hip replacement |
| Q42329962 | Senescence-associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells |
| Q29615559 | Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor |
| Q36982102 | Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells |
| Q33527140 | Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis |
| Q33851700 | Short telomeres compromise β-cell signaling and survival |
| Q36740590 | Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice |
| Q24558758 | Smurf2 up-regulation activates telomere-dependent senescence |
| Q33112680 | Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. |
| Q35549158 | Telomere dysfunction causes alveolar stem cell failure |
| Q46515985 | Telomere-surrounding regions are transcription-permissive 3D nuclear compartments in human cells |
| Q36904429 | Telomeres and age-related disease: how telomere biology informs clinical paradigms |
| Q36530781 | The Effect of Culture on Human Bone Marrow Mesenchymal Stem Cells: Focus on DNA Methylation Profiles |
| Q31108150 | The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes |
| Q36791542 | The effect of cell-matrix interactions and aging on the malignant process |
| Q34319346 | The evolutionary dynamics of eukaryotic gene order |
| Q34481078 | The expression signature of in vitro senescence resembles mouse but not human aging |
| Q34769742 | The identification of senescence-specific genes during the induction of senescence in prostate cancer cells |
| Q34041036 | The role of senescent cells in ageing |
| Q29620106 | The senescence-associated secretory phenotype: the dark side of tumor suppression |
| Q47971896 | The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells |
| Q24632444 | The telomere syndromes |
| Q34212773 | Therapy-Induced Senescence in Cancer |
| Q51501058 | Transcription factor Sp1 prevents TRF2(ΔBΔM)-induced premature senescence in human diploid fibroblasts. |
| Q40249879 | Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization |
| Q33763939 | Transcriptional networks and cellular senescence in human mammary fibroblasts |
| Q41464237 | Tumor cell senescence response produces aggressive variants. |
| Q34958852 | Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes |
| Q36189815 | Unfolding the story of chromatin organization in senescent cells |
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