| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M200373200 |
| P698 | PubMed publication ID | 11836256 |
| P2093 | author name string | Steven R Schwarze | |
| David F Jarrard | |||
| James D Brooks | |||
| Samuel E DePrimo | |||
| Lisa M Grabert | |||
| Vivian X Fu | |||
| P2860 | cites work | Bypass of Senescence After Disruption of p21 CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts | Q42815554 |
| Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. | Q44816904 | ||
| Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling | Q22003910 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription | Q24554293 | ||
| Significance analysis of microarrays applied to the ionizing radiation response | Q24606608 | ||
| RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage | Q24628907 | ||
| Cluster analysis and display of genome-wide expression patterns | Q24644463 | ||
| Insulin-like growth factor binding proteins: new proteins, new functions | Q28144966 | ||
| Systematic variation in gene expression patterns in human cancer cell lines | Q28145747 | ||
| Insulin-like growth factor II (IGF-II) | Q28281165 | ||
| The transcriptional program in the response of human fibroblasts to serum | Q28292705 | ||
| The serial cultivation of human diploid cell strains | Q29547356 | ||
| Gene expression profile of aging and its retardation by caloric restriction | Q29614554 | ||
| Use of a cDNA microarray to analyse gene expression patterns in human cancer | Q29618814 | ||
| Overcoming cellular senescence in human cancer pathogenesis | Q30448767 | ||
| Genetic analysis of indefinite division in human cells: identification of four complementation groups | Q33640611 | ||
| Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis | Q33853206 | ||
| The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis | Q33888765 | ||
| Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging | Q33946993 | ||
| Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor | Q33961286 | ||
| Genomewide scan for prostate cancer-aggressiveness loci. | Q34141936 | ||
| Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. | Q34350117 | ||
| Cellular senescence, cancer and aging: the telomere connection | Q34416433 | ||
| Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice | Q34420980 | ||
| Cellular senescence as a tumor-suppressor mechanism | Q34421790 | ||
| Senescence of human fibroblasts induced by oncogenic Raf | Q35210205 | ||
| In vivo expression of the novel CXC chemokine BRAK in normal and cancerous human tissue | Q35745538 | ||
| rhoB Encoding a UV-inducible Ras-related Small GTP-binding Protein Is Regulated by GTPases of the Rho Family and Independent of JNK, ERK, and p38 MAP Kinase | Q36894019 | ||
| Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3 | Q39455066 | ||
| Role of cyclin-dependent kinase inhibitors in the growth arrest at senescence in human prostate epithelial and uroepithelial cells | Q40758263 | ||
| Cell immortalization as a key, rate-limiting event in malignant transformation: approaches toward a molecular genetic analysis | Q40885678 | ||
| Aging and cancer: the double-edged sword of replicative senescence | Q41430192 | ||
| Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells | Q41442148 | ||
| Growth kinetics and differentiation in vitro of normal human uroepithelial cells on collagen gel substrates in defined medium | Q42523184 | ||
| P433 | issue | 17 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cellular senescence | Q9075999 |
| P304 | page(s) | 14877-14883 | |
| P577 | publication date | 2002-02-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells | |
| P478 | volume | 277 |
| Q57961581 | A Loss of Insulin-like Growth Factor-2 Imprinting Is Modulated by CCCTC-binding Factor Down-regulation at Senescence in Human Epithelial Cells |
| Q51740038 | APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells |
| Q39205118 | Altered apoptotic responses in neurons lacking RhoB GTPase |
| Q54373944 | An intronic polymorphism rs2237062 in the CXCL14 gene influences HBV-related HCC progression in Chinese population |
| Q37327005 | Androgen control of cell proliferation and cytoskeletal reorganization in human fibrosarcoma cells: role of RhoB signaling. |
| Q55302816 | B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3. |
| Q35815320 | Cellular senescence and organismal aging |
| Q40266725 | Characterization of the activities of p21Cip1/Waf1 promoter-driven reporter systems during camptothecin-induced senescence-like state of BHK-21 cells |
| Q42716214 | Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts |
| Q30829491 | Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs |
| Q33258688 | Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma |
| Q43240843 | CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer |
| Q39956460 | Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. |
| Q37246647 | Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. |
| Q36199857 | Decreased Skp2 Expression Is Necessary but Not Sufficient for Therapy-Induced Senescence in Prostate Cancer |
| Q90571258 | Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells |
| Q46845463 | Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker |
| Q35067854 | Down-regulation of Filamin A interacting protein 1-like Is associated with promoter methylation and an invasive phenotype in breast, colon, lung and pancreatic cancers [corrected] |
| Q35169206 | Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer. |
| Q36608493 | Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo |
| Q28275900 | EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-I |
| Q83934412 | Efficient Inhibition of Ovarian Cancer by Truncation Mutant of FILIP1L Gene Delivered by Novel Biodegradable Cationic Heparin-Polyethyleneimine Nanogels |
| Q39501315 | Embryonic stem‐cell‐preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells |
| Q34073234 | Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3 |
| Q33551404 | Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells |
| Q44488215 | Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. |
| Q37710265 | Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis |
| Q37038009 | Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy. |
| Q38337784 | Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system |
| Q40480355 | Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. |
| Q35141734 | IGFBP-3 is a metastasis suppression gene in prostate cancer |
| Q34151999 | IGFBP-3, a marker of cellular senescence, is overexpressed in human papillomavirus-immortalized cervical cells and enhances IGF-1-induced mitogenesis |
| Q34171551 | IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasia |
| Q40281659 | Id-1 modulates senescence and TGF-beta1 sensitivity in prostate epithelial cells |
| Q39734867 | Inhibitor of differentiation 1 (ID1) promotes cell survival and proliferation of prostate epithelial cells |
| Q34353406 | Insights into gene expression changes impacting B-cell transformation: cross-species microarray analysis of bovine leukemia virus tax-responsive genes in ovine B cells |
| Q37428196 | Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro |
| Q39437475 | L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells. |
| Q81242898 | Large-scale search of single nucleotide polymorphisms for hepatocellular carcinoma susceptibility genes in patients with hepatitis C |
| Q38730507 | Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone. |
| Q38072352 | Markers of Cellular Senescence |
| Q40091069 | Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles |
| Q35063883 | New molecular methods for classification, diagnosis and therapy prediction of hematological malignancies |
| Q44375183 | Oxidative Stress in Stem Cell Aging. |
| Q37412844 | Perspectives in mammalian IGFBP-3 biology: local vs. systemic action |
| Q45282577 | Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77. |
| Q37310063 | Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications |
| Q34665706 | Regulation of Senescence in Cancer and Aging |
| Q30426736 | Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells |
| Q37467489 | Resveratrol-induced gene expression profiles in human prostate cancer cells |
| Q34352155 | Secretome analysis of ionizing radiation‐induced senescent cancer cells reveals that secreted RKIP plays a critical role in neighboring cell migration |
| Q34868217 | Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci |
| Q30485600 | Senescent keratinocytes die by autophagic programmed cell death. |
| Q33527140 | Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis |
| Q34382668 | Sensitivity to TOP2 Targeting Chemotherapeutics Is Regulated by Oct1 and FILIP1L |
| Q38302138 | Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24. |
| Q35549516 | Smurf2‐mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence |
| Q42084582 | The ING tumor suppressors in cellular senescence and chromatin |
| Q39944686 | The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells |
| Q41721652 | The epigenetic regulation of CXCL14 plays a role in the pathobiology of oral cancers |
| Q34481078 | The expression signature of in vitro senescence resembles mouse but not human aging |
| Q34769742 | The identification of senescence-specific genes during the induction of senescence in prostate cancer cells |
| Q29620106 | The senescence-associated secretory phenotype: the dark side of tumor suppression |
| Q35963298 | The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells |
| Q27027457 | Therapeutic targeting of replicative immortality |
| Q34212773 | Therapy-Induced Senescence in Cancer |
| Q33763939 | Transcriptional networks and cellular senescence in human mammary fibroblasts |
| Q39061155 | Truncation of inhibitor of growth family protein 5 effectively induces senescence, but not apoptosis in human tongue squamous cell carcinoma cell line |
| Q39502702 | Upregulation of prostate-derived Ets factor by luteolin causes inhibition of cell proliferation and cell invasion in prostate carcinoma cells. |
Search more.