scholarly article | Q13442814 |
P2093 | author name string | Howard BH | |
Ogryzko VV | |||
Hirai TH | |||
Barbie DA | |||
Russanova VR | |||
P2860 | cites work | The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest | Q24321861 |
A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
Epigenetic inheritance of transcriptional states in S. cerevisiae | Q27934639 | ||
Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation | Q27937778 | ||
Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts | Q28259026 | ||
The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin | Q28285261 | ||
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon | Q28639770 | ||
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae | Q29397443 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
Telomere length predicts replicative capacity of human fibroblasts | Q29615745 | ||
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A | Q29617379 | ||
Human skin fibroblasts in vitro differentiate along a terminal cell lineage | Q33632077 | ||
The effect of modifiers of position-effect variegation on the variegation of heterochromatic genes of Drosophila melanogaster | Q33958187 | ||
A cytogenetic and genetic characterization of a group of closely linked second chromosome mutations that suppress position-effect variegation in Drosophila melanogaster | Q33959013 | ||
Telomere reduction in human colorectal carcinoma and with ageing | Q34037761 | ||
Protein oxidation and aging | Q34243989 | ||
Effects of sodium butyrate, a new pharmacological agent, on cells in culture | Q34249353 | ||
Sodium butyrate inhibits histone deacetylation in cultured cells | Q34266043 | ||
Oxidative DNA damage and senescence of human diploid fibroblast cells. | Q34323707 | ||
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. | Q35217164 | ||
Position effect variegation and chromatin proteins | Q35284118 | ||
A rosy future for heterochromatin | Q35409211 | ||
Silencers, silencing, and heritable transcriptional states | Q35655395 | ||
Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate | Q35691655 | ||
Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process | Q35844125 | ||
Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia | Q35875086 | ||
Silencing: the establishment and inheritance of stable, repressed transcription states | Q36354856 | ||
Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase | Q36634188 | ||
Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging | Q36658009 | ||
Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes | Q36686434 | ||
DNA methylation and cellular ageing | Q36706946 | ||
Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging | Q36761547 | ||
Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences | Q37585853 | ||
Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation | Q37639646 | ||
Cellular senescence: a reflection of normal growth control, differentiation, or aging? | Q37766091 | ||
Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis | Q37802708 | ||
Replicative senescence: the human fibroblast comes of age. | Q37951214 | ||
On the biological role of histone acetylation | Q38140863 | ||
Doubling potential, calendar time, and senescence of human diploid cells in culture | Q38527276 | ||
Subcellular localization of the retinoblastoma protein | Q39257082 | ||
Erythroleukemic Differentiation | Q39757105 | ||
Aging of Cells in Culture | Q40111153 | ||
White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila | Q40625724 | ||
Replicative senescence of human fibroblast-like cells in culture | Q40825818 | ||
Effect of ageing on reactivation of the human X-linked HPRT locus | Q41253774 | ||
Investigation of the "variable spreading" of X inactivation into a translocated autosome | Q41312220 | ||
Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance | Q41452295 | ||
Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1. | Q41668628 | ||
The phosphorylation state of the retinoblastoma (RB) protein in G0/G1 is dependent on growth status | Q41696410 | ||
Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization | Q41710416 | ||
Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts | Q41725165 | ||
Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts | Q41748100 | ||
Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells | Q42491123 | ||
Control of cell proliferation in senescent cells | Q43667166 | ||
Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. | Q44049265 | ||
The effect of sodium butyrate on histone modification | Q44252246 | ||
Proliferative capacity and DNA content of aging human diploid cells in culture: a cytophotometric and autoradiographic analysis | Q44495604 | ||
Myogenic stem cell commitment probability remains constant as a function of organismal and mitotic age | Q44802212 | ||
Isolation of a population of transiently transfected quiescent and senescent cells by magnetic affinity cell sorting | Q45092131 | ||
Reinitiation of host DNA synthesis in senescent human diploid cells by infection with simian virus 40 | Q45798767 | ||
Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI-38 cells by simian virus 40 infection | Q45838097 | ||
Stable Lyonization of X-linked pgk-1 gene during aging in normal tissues and tumors of mice carrying Searle's translocation | Q46435749 | ||
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products | Q52061971 | ||
A reconsideration of the mechanism of position effect. | Q52542072 | ||
Regulating genes by packaging domains: bits of heterochromatin in euchromatin? | Q52545879 | ||
Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate | Q53473170 | ||
Senescence of cultured human fibroblasts: mitotic versus metabolic time | Q53809997 | ||
Age related reactivation of an X-linked gene | Q59096334 | ||
Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence? | Q60284719 | ||
A role for both RB and p53 in the regulation of human cellular senescence | Q64378339 | ||
Correlation between the presence of T-antigen and the reinitiation of host DNA synthesis in senescent human diploid fibroblasts after SV40 infection | Q67285214 | ||
Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: Variable response to drug treatment and withdrawal | Q67670897 | ||
Telomere positional effects and the regulation of cellular senescence | Q68007322 | ||
Position effect variegation in the mouse | Q68841969 | ||
DNA hypermethylation in sodium butyrate-treated WI-38 fibroblasts | Q68955298 | ||
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation | Q68978483 | ||
Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells | Q69100955 | ||
Dissociation of senescence-associated changes in differentiated gene expression and replicative senescence in cultured adrenocortical cells | Q69456743 | ||
DNA microdensitometry as a measure of cycling-non-cycling activity in aged human diploid cells in culture | Q70029129 | ||
Induction of differentiation in HL60 leukaemic cells: a cell cycle dependent all-or-none event | Q70789733 | ||
The proliferative potential of chick embryo fibroblasts: population doublings vs. time in culture | Q71470853 | ||
Butyrate suppression of position-effect variegation in Drosophila melanogaster | Q71508805 | ||
DNA methylation decreases in aging but not in immortal cells | Q71718599 | ||
Genotype-specific modifiers of transgene methylation and expression in the zebrafish, Danio rerio | Q72237925 | ||
Histone deacetylation is required for the maturation of newly replicated chromatin | Q72797417 | ||
The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression | Q72863039 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | human fibroblast | Q101404861 |
P304 | page(s) | 5210-5218 | |
P577 | publication date | 1996-09-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent | |
P478 | volume | 16 |
Q36592145 | A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells |
Q37589239 | A model of sensitivity and resistance to histone deacetylase inhibitors in diffuse large B cell lymphoma: Role of cyclin-dependent kinase inhibitors |
Q33536846 | A reassessment of the telomere hypothesis of senescence |
Q40160277 | Accumulation of multiple forms of lamin A with down-regulation of FACE-1 suppresses growth in senescent human cells |
Q38024561 | Aging epigenetics: Causes and consequences |
Q35032470 | Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity |
Q24614474 | Bmi1, stem cells, and senescence regulation |
Q34801698 | Cancer and aging: a model for the cancer promoting effects of the aging stroma |
Q37385995 | Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network |
Q90417537 | Cellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review |
Q34106524 | Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes |
Q36853695 | Cellular senescence and chromatin structure |
Q37678205 | Cellular senescence in osteoarthritis pathology. |
Q35581237 | Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism |
Q38359181 | Cellular senescence: a hitchhiker's guide. |
Q29615561 | Cellular senescence: when bad things happen to good cells |
Q48789063 | Changes in histone acetylation during postovulatory aging of mouse oocyte |
Q33588661 | Chromatin modifications: the driving force of senescence and aging? |
Q37684600 | Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer |
Q37457395 | Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence |
Q51830302 | Cyclophosphamide induces premature senescence in normal human fibroblasts by activating MAP kinases |
Q36360646 | DNA damage, cellular senescence and organismal ageing: causal or correlative? |
Q80196205 | Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions |
Q40202977 | Dissecting the senescence-like program in tumor cells activated by Ras signaling |
Q35915738 | Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cells |
Q40722401 | Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene |
Q74297486 | Enhanced oxidative stress and accelerated cellular senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts |
Q36786281 | Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease? |
Q53335869 | Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. |
Q59136748 | Epigenetics in Cardiac Fibrosis: Emphasis on Inflammation and Fibroblast Activation |
Q46790468 | Ethanol extract of Dalbergia odorifera protects skin keratinocytes against ultraviolet B-induced photoaging by suppressing production of reactive oxygen species |
Q40715420 | Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis |
Q48025794 | Features of replicative senescence induced by direct addition of antennapedia‐p16INK4A fusion protein to human diploid fibroblasts |
Q41652230 | Fiber-derived butyrate and the prevention of colon cancer |
Q34025754 | Four faces of cellular senescence |
Q34214183 | From cells to organisms: can we learn about aging from cells in culture? |
Q24810847 | HDACs and the senescent phenotype of WI-38 cells |
Q28585449 | Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice |
Q40450785 | Histone deacetylase inhibitors differentially stabilize acetylated p53 and induce cell cycle arrest or apoptosis in prostate cancer cells. |
Q40565411 | Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock |
Q45870370 | Histone deacetylase inhibitors preferentially augment transient transgene expression in human dermal fibroblasts |
Q74063080 | Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2 |
Q33926323 | Histone deacetylases, transcriptional control, and cancer |
Q42153124 | Histone modifications in senescence-associated resistance to apoptosis by oxidative stress |
Q24297146 | Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence |
Q39952364 | ING1a expression increases during replicative senescence and induces a senescent phenotype |
Q74434059 | In vitro acquired cellular senescence and aging-specific phenotype can be distinguished on the basis of specific mRNA expression |
Q77593535 | In vitro effects of cholesteryl butyrate solid lipid nanospheres as a butyric acid pro-drug on melanoma cells: evaluation of antiproliferative activity and apoptosis induction |
Q40662677 | Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos |
Q28377610 | Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53 |
Q30983475 | Induction of senescence-associated genes by 5-bromodeoxyuridine in HeLa cells. |
Q35185629 | Involvement of the INK4a/Arf gene locus in senescence |
Q34537637 | Lung fibroblasts from patients with emphysema show markers of senescence in vitro |
Q35092329 | MHC class II regulation by epigenetic agents and microRNAs |
Q37071643 | MRGing chromatin dynamics and cellular senescence |
Q36405926 | MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation |
Q41441652 | Mechanisms of cellular senescence |
Q36568015 | Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype |
Q36667831 | Molecular signaling and genetic pathways of senescence: Its role in tumorigenesis and aging |
Q26853406 | Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis) |
Q40137660 | Multiple Molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo |
Q24603335 | Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A |
Q24815695 | Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor |
Q26750501 | Old cells, new tricks: chromatin structure in senescence |
Q37401600 | Oncogene-induced cellular senescence elicits an anti-Warburg effect |
Q24324559 | Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a |
Q33390343 | Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis |
Q36647415 | Oxygen free radicals in cell senescence: are they signal transducers? |
Q34926594 | PML a target of translocations in APL is a regulator of cellular senescence. |
Q35639923 | PPARδ coordinates angiotensin II-induced senescence in vascular smooth muscle cells through PTEN-mediated inhibition of superoxide generation |
Q89999356 | PRMT7 methylates and suppresses GLI2 binding to SUFU thereby promoting its activation |
Q22003910 | Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling |
Q36444277 | Premature senescence of endothelial cells: Methusaleh's dilemma |
Q37229309 | Progeroid syndromes: probing the molecular basis of aging? |
Q34430830 | Putting the stress on senescence |
Q28074230 | Redox control of senescence and age-related disease |
Q34665706 | Regulation of Senescence in Cancer and Aging |
Q33961286 | Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor |
Q34254621 | Regulation of cellular senescence by p53. |
Q37478008 | Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation |
Q37317571 | Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence |
Q40728995 | Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells |
Q34012414 | Role of p14(ARF) in replicative and induced senescence of human fibroblasts |
Q34273466 | Seizing of T cells by human T-cell leukemia/lymphoma virus type 1. |
Q38603571 | Senescence and cancer: An evolving inflammatory paradox |
Q47106101 | Senescence and tumor suppression. |
Q26742060 | Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy |
Q38961328 | Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings |
Q30577529 | Senescence-associated β-galactosidase activity marks the visceral endoderm of mouse embryos but is not indicative of senescence |
Q34868217 | Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci |
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Q40780560 | Senescent cells are resistant to death despite low Bcl-2 level |
Q38968807 | Senescent stroma promotes prostate cancer progression: the role of miR-210. |
Q34526096 | Sensitive Detection and Monitoring of Senescence-Associated Secretory Phenotype by SASP-RAP Assay |
Q28068732 | Small molecule compounds that induce cellular senescence |
Q42797574 | Sodium Butyrate Induces NIH3T3 Cells to Senescence-like State and Enhances Promoter Activity of p21WAF/CIP1in p53-Independent Manner |
Q28139194 | Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1 |
Q52827047 | Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts |
Q37082277 | Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation |
Q27683746 | Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues |
Q37156197 | Sublethal oxidative stress induces the premature senescence of human mesenchymal stem cells derived from endometrium |
Q26853394 | Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications |
Q40935135 | Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer |
Q38346325 | The Intricate Interplay between Mechanisms Underlying Aging and Cancer |
Q87353450 | The PPARδ-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependent |
Q41583618 | The biology of replicative senescence |
Q43842959 | The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H10 synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study |
Q41604621 | The heterochromatin loss model of aging |
Q33807763 | The inflammatory network: bridging senescent stroma and epithelial tumorigenesis |
Q34440758 | The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors. |
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Q35163096 | Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells |
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Q39649107 | Two‐fold elevation of expression of FoxM1 transcription factor in mouse embryonic fibroblasts enhances cell cycle checkpoint activity by stimulating p21 and Chk1 transcription |
Q34571389 | Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence |
Q42170797 | Valproic acid resensitizes cisplatin-resistant ovarian cancer cells |
Q40773189 | mRNA levels of the differentiation-associated linker histone variant H1 zero in mitotically active and postmitotic senescent human diploid fibroblast cell populations |
Q24339391 | p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence |
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