The therapeutic potential of the cannabinoids in neuroprotection

scientific article

The therapeutic potential of the cannabinoids in neuroprotection is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/13543784.11.10.1365
P698PubMed publication ID12387700

P2093author name stringRobert I Grundy
P2860cites workExpression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulationsQ24309438
Molecular cloning of a human cannabinoid receptor which is also expressed in testisQ24337626
Cannabinoid receptor localization in brainQ24558751
Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blockerQ24601670
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptorsQ24642509
Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidantsQ24685540
Cannabinoids control spasticity and tremor in a multiple sclerosis modelQ28138564
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptorQ28218654
Structure of a cannabinoid receptor and functional expression of the cloned cDNAQ28240076
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1Q28270721
Molecular characterization of a peripheral receptor for cannabinoidsQ28298338
Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60Q28374277
Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulataQ28377147
The non-psychotropic cannabinoid (+)-(3S,4S)-7-hydroxy-Δ6-tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates receptor-mediated neurotoxicity in primary cultures of rat forebrainQ29012303
Isolation and structure of a brain constituent that binds to the cannabinoid receptorQ29547476
Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and developmentQ31522100
The cannabinoid system and cytokine networkQ34040002
An endogenous cannabinoid (2-AG) is neuroprotective after brain injuryQ34093755
Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective propertiesQ34133453
Cerebral ischemia and inflammationQ34139882
The role of cannabinoids in neurodegenerative diseasesQ34268475
Cannabinoids and neuroprotectionQ34520143
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.Q34602111
Pharmacological interventions for stroke: failures and futureQ34628650
Tetrahydrocannabinol for tremor in multiple sclerosisQ34708416
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous systemQ34745063
In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileumQ35028193
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cellsQ37599138
Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.Q40743568
Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectantQ41355460
Effects of CB(1) cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activityQ42478605
Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease miceQ42490465
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.Q42517324
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's diseaseQ43504648
Striatal cannabinoid CB1 receptor mRNA expression is decreased in the reserpine-treated rat model of Parkinson's disease.Q43611998
Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's diseaseQ43669613
Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.Q43683165
Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicityQ43713675
Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus.Q43742950
Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegenerationQ43752352
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot studyQ43820144
Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.Q44330257
Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitisQ44929830
Selective vulnerability in Huntington's disease: preferential loss of cannabinoid receptors in lateral globus pallidus.Q45289172
The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's diseaseQ45300428
Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's diseaseQ45305400
The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathwayQ45753821
Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytesQ45761757
Cannabinoid receptors and immunityQ48029970
A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat.Q48366948
Nabilone in the treatment of multiple sclerosis.Q55065083
Isolation, Structure, and Partial Synthesis of an Active Constituent of HashishQ55871276
Cannabinoid CB1 Receptor Expression in Rat Spinal CordQ56827591
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcannabinoidsQ422936
P304page(s)1365-1374
P577publication date2002-10-01
P1433published inExpert Opinion on Investigational DrugsQ5421208
P1476titleThe therapeutic potential of the cannabinoids in neuroprotection
P478volume11

Reverse relations

cites work (P2860)
Q34581675Acute and non-acute effects of cannabis on brain functioning and neuropsychological performance
Q37087780Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model
Q38287134Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways.
Q36977766Cannabinoids and neuroprotection in basal ganglia disorders.
Q24241582Cannabinoids for the treatment of dementia
Q24242873Cannabinoids for the treatment of dementia
Q94337892Cannabinoids for the treatment of dementia
Q36829594Cannabis and Ecstasy/MDMA (3,4-methylenedioxymethamphetamine): an analysis of their neuropsychobiological interactions in recreational users
Q92310219Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives
Q34278963Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors
Q36779439Drugs of abuse and the aging brain
Q45176545Ecstasy/MDMA and cannabis: the complexities of their interactive neuropsychobiological effects.
Q38615088Endo-cannabinoids system and the toxicity of cannabinoids with a biotechnological approach
Q34967151Endocannabinoid signaling in midbrain dopamine neurons: more than physiology?
Q34858094Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo
Q36787826Impact of HIV and a history of marijuana dependence on procedural learning among individuals with a history of substance dependence
Q34266329Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271
Q46426378Pattern of cannabis use in ecstasy polydrug users: moderate cannabis use may compensate for self-rated aggression and somatic symptoms
Q39834593Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells.
Q35753458Remyelinating and neuroprotective treatments in multiple sclerosis
Q51980131The effects of concurrent cannabis use among ecstasy users: neuroprotective or neurotoxic?
Q24648473The endocannabinoid system as an emerging target of pharmacotherapy
Q48097673The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis
Q34472972The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats
Q34212503The therapeutic potential of cannabis
Q35094657The therapeutic potential of cannabis in multiple sclerosis