Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's disease

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Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's disease is …
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scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(01)03403-5
P698PubMed publication ID11864629

P50authorJosé J. LucasQ42463527
P2093author name stringYamamoto A
Berrendero F
Ramos JA
Fernández-Ruiz JJ
Lastres-Becker I
Martín-Aparicio E
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Differential loss of striatal projection neurons in Huntington diseaseQ33637273
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Brain cannabinoid systems as targets for the therapy of neurological disordersQ34492167
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.Q34602111
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous systemQ34745063
Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrainQ37413174
Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistryQ38331458
The activation of cannabinoid receptors in striatonigral GABAergic neurons inhibited GABA uptake.Q42450193
Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamenQ42487505
Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease miceQ42490465
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.Q43792416
Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.Q44330257
Differences in G-protein activation by mu- and delta-opioid, and cannabinoid, receptors in rat striatumQ44343153
Selective vulnerability in Huntington's disease: preferential loss of cannabinoid receptors in lateral globus pallidus.Q45289172
Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.Q45290294
Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's diseaseQ45291252
Advances in Huntington's disease: implications for experimental therapeuticsQ45296397
The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's diseaseQ45300428
Ipsilateral turning behavior induced by unilateral microinjections of a cannabinoid into the rat subthalamic nucleusQ47963301
Neuron-specific enolase (NSE) and non-neuronal enolase (NNE) mRNAs are co-expressed in neurons of the rat cerebellum: in situ hybridization histochemistryQ48255621
Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituentQ48332786
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicingQ48384593
3-Nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration.Q48403701
Role of the subthalamic nucleus in cannabinoid actions in the substantia nigra of the rat.Q48786464
Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus.Q48962147
Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents.Q52060269
Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function.Q54001516
Chronic CP-55,940 alters cannabinoid receptor mRNA in the rat brain: an in situ hybridization studyQ72110282
delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of ratsQ72270865
The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neuronsQ72302141
Activational role of cannabinoids on movementQ73575705
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectHuntington's diseaseQ190564
cannabinoid receptorQ421237
cannabinoidsQ422936
CNR2Q17907844
P1104number of pages7
P304page(s)236-242
P577publication date2002-03-01
P1433published inBrain ResearchQ4955782
P1476titleLoss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's disease
P478volume929

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