The lectin pathway of complement and rheumatic heart disease.

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The lectin pathway of complement and rheumatic heart disease. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FPED.2014.00148
P932PMC publication ID4300866
P698PubMed publication ID25654073
P5875ResearchGate publication ID272081321

P50authorSandra Jeremias dos Santos CatarinoQ56946998
Angelica Beate Winter BoldtQ77668062
Iara Jose de Messias-ReasonQ98393146
Isabela GoeldnerQ115138632
P2093author name stringMarcia Holsbach Beltrame
P2860cites workNon-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolinQ21133812
Proteolytic activities of two types of mannose-binding lectin-associated serine proteaseQ24290100
MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathwayQ24291529
Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activationQ24299377
L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complementQ24304072
A second serine protease associated with mannan-binding lectin that activates complementQ24311275
A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsoninQ24318926
Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathwayQ24337732
MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory findings of Carnevale, Malpuech, OSA, and Michels syndromesQ24607800
Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndromeQ24613690
A novel mannose-binding lectin/ficolin-associated protein is highly expressed in heart and skeletal muscle tissues and inhibits complement activationQ24633142
Association of mannose-binding lectin gene polymorphism but not of mannose-binding serine protease 2 with chronic severe aortic regurgitation of rheumatic etiologyQ24647006
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cellsQ24670661
The human mannose-binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10Q24681840
The role of complement system in septic shockQ27027974
Local inflammation induces complement crosstalk which amplifies the antimicrobial responseQ27318134
Structure of a C-type mannose-binding protein complexed with an oligosaccharideQ27642164
Trivalent recognition unit of innate immunity system: crystal structure of trimeric human M-ficolin fibrinogen-like domainQ27643220
Carbohydrate Recognition Properties of Human Ficolins: GLYCAN ARRAY SCREENING REVEALS THE SIALIC ACID BINDING SPECIFICITY OF M-FICOLINQ27658764
Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2Q27678585
The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) SyndromeQ27678744
Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin familyQ28115725
Mannose-binding lectin polymorphisms in clinical tuberculosisQ28203157
Complement. First of two partsQ28210663
Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotypeQ28238306
Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African childrenQ28259433
MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activationQ28264948
Coding and non-coding polymorphisms in the lectin pathway activator L-ficolin gene in 188 Dutch blood bank donorsQ28265418
L-ficolin is a pattern recognition molecule specific for acetyl groupsQ28279109
Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantationQ28286627
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement systemQ28289357
Functional polymorphisms in the FCN2 gene are not associated with invasive pneumococcal diseaseQ28294642
The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levelsQ28294974
Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activationQ28574745
Molecular determinants of oligomer formation and complement fixation in mannose-binding proteinsQ28575621
Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement depositionQ28610880
Serum concentration of Hakata antigen, a member of the ficolins, is linked with inhibition of Aerococcus viridans growthQ28610896
Human M-ficolin is a secretory protein that activates the lectin complement pathwayQ28610924
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infectionQ28727502
Complement: a key system for immune surveillance and homeostasisQ29615484
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2Q30519464
Posttranslational modifications in human plasma MBL and human recombinant MBL.Q33272929
Phylogenetic nomenclature and evolution of mannose-binding lectin (MBL2) haplotypesQ33577516
Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolinQ33795274
Hakata antigen, a new member of the ficolin/opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bileQ33862372
Changes in the mannan binding lectin (MBL) concentration in human milk during lactation.Q33962411
Mannan-binding lectin enhances susceptibility to visceral leishmaniasisQ34008749
The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasmaQ34010473
Relevance of the lectin pathway of complement in rheumatic diseasesQ34031016
Complement and its role in innate and adaptive immune responsesQ34088142
Collections and ficolins: humoral lectins of the innate immune defenseQ34169976
Ficolins in complement activationQ38041820
Toward a structure-based comprehension of the lectin pathway of complementQ38126258
If there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it?Q38164341
Ficolins and infectious diseasesQ38180985
A vital role for complement in heart diseaseQ38231108
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphismsQ38305434
Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain reaction with sequence-specific primersQ38310018
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.Q38332617
Mannose-binding lectin without the aid of its associated serine proteases alters lipopolysaccharide-mediated cytokine/chemokine secretion from human endothelial cellsQ38505801
Diversity of the MBL2 gene in various Brazilian populations and the case of selection at the mannose-binding lectin locusQ38913652
Association of a new mannose-binding lectin variant with severe malaria in Gabonese childrenQ38913656
Functional haplotypes that produce normal ficolin-2 levels protect against clinical leprosyQ38966320
The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigmQ38966324
Ficolin-2 levels and genetic polymorphisms of FCN2 in malariaQ38997834
Recognition of plasmodium falciparum proteins by mannan-binding lectin, a component of the human innate immune systemQ39140090
Schistosoma mansoni: adhesion of mannan-binding lectin to surface glycoproteins of cercariae and adult wormsQ39140094
Anti-endothelial cell antibodies in rheumatic heart diseaseQ39196176
Ficolin 2 (FCN2) functional polymorphisms and the risk of rheumatic fever and rheumatic heart diseaseQ39247371
Characteristics and biological variations of M-ficolin, a pattern recognition molecule, in plasmaQ39717405
M-ficolin in the neonatal period: Associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitisQ39835929
Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activityQ39881059
Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency stateQ40015050
Functional MASP2 gene polymorphism in patients with history of rheumatic feverQ40120882
Association of MASP2 polymorphisms and protein levels with rheumatic fever and rheumatic heart diseaseQ40186841
Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and womenQ40298826
The association between mannose-binding lectin gene polymorphism and rheumatic heart disease.Q40462107
Significantly increased levels of mannose-binding lectin (MBL) in rheumatic heart disease: a beneficial role for MBL deficiencyQ40521039
Prospective analysis of mannose-binding lectin genotypes and coronary artery disease in American Indians: the Strong Heart StudyQ40536982
Human mannose-binding protein gene is regulated by interleukins, dexamethasone and heat shockQ41530914
The alternative pathway C3/C5 convertase: chemical basis of factor B activationQ41688985
L-Ficolin/mannose-binding lectin-associated serine protease complexes bind to group B streptococci primarily through N-acetylneuraminic acid of capsular polysaccharide and activate the complement pathwayQ41911504
The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response.Q41939432
Lectin pathway of complement activation and relation with clinical complications in critically ill childrenQ42244078
Mannose binding lectin and mannose binding lectin-associated serine protease-2 genes polymorphisms in human T-lymphotropic virus infection.Q42283356
Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infectionQ42286620
Heart valve structure: a predisposing factor for rheumatic heart diseaseQ42830829
Functional estimation of mannose binding lectin associated serine protease (MBL-MASPs) in human serum.Q43234844
Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP.Q43278864
Inhibition of mannose-binding lectin reduces postischemic myocardial reperfusion injuryQ43740164
Evolutionary insights into the high worldwide prevalence of MBL2 deficiency allelesQ44096290
Plasma levels of mannan-binding lectin (MBL)-associated serine proteases (MASPs) and MBL-associated protein in cardio- and cerebrovascular diseases.Q44400729
L-ficolin (ficolin-2) insufficiency is associated with combined allergic and infectious respiratory disease in childrenQ44437093
Inherited deficiency of mannan-binding lectin-associated serine protease 2.Q44540603
Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complementQ44840259
Serum mannan-binding lectin-associated serine protease 2 levels in colorectal cancer: relation to recurrence and mortalityQ45299103
Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2.Q46477709
Interplay between promoter and structural gene variants control basal serum level of mannan-binding proteinQ46487298
Leishmania (Viannia) braziliensis: interaction of mannose-binding lectin with surface glycoconjugates and complement activation. An antibody-independent defence mechanismQ46692780
L-ficolin binding and lectin pathway activation by acetylated low-density lipoprotein.Q46887320
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway componentsQ47659798
Phospholipid-binding activity of human mannan-binding lectinQ47872158
L-ficolin in children with recurrent respiratory infectionsQ47895660
Innate immune collectins bind nucleic acids and enhance DNA clearance in vitroQ47916786
Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritisQ49037435
Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colonization in cystic fibrosis patients.Q49155500
Investigations on the pattern recognition molecule M-ficolin: quantitative aspects of bacterial binding and leukocyte associationQ50335844
Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function.Q50785735
Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production.Q50865174
Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein.Q51829664
Increased complement classical and mannan-binding lectin pathway activities in schizophrenia.Q51914518
Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi.Q53368984
Serum lectin with known structure activates complement through the classical pathway.Q53877303
MAp19, the alternative splice product of the MASP2 gene.Q54351972
MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease.Q54378107
Humoral pattern recognition and the complement system.Q34344598
Mannose-binding lectin deficiency is associated with myocardial infarction: the HUNT2 study in NorwayQ34359560
The role of c5b-9 terminal complement complex in activation of the cell cycle and transcriptionQ34375499
M-ficolin, an innate immune defence molecule, binds patterns of acetyl groups and activates complementQ34469825
The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cellsQ34624161
Association of L-ficolin levels and FCN2 genotypes with chronic Chagas diseaseQ34672811
Association of ficolin-3 with severity and outcome of chronic heart failureQ34676160
High-producing MBL2 genotypes increase the risk of acute and chronic carditis in patients with history of rheumatic feverQ34792551
Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5Q34919024
Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44Q34984382
A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectinsQ35089426
Anti-microbial activities of mannose-binding lectinQ35187396
Mannan binding lectin deficiency and concomitant immunodefectsQ35258823
Complement inhibitor C4b-binding protein-friend or foe in the innate immune system?Q35741515
Complement activation after oxidative stress: role of the lectin complement pathwayQ35810112
Human L-ficolin (ficolin-2) and its clinical significanceQ35829788
MASP-2 activation is involved in ischemia-related necrotic myocardial injury in humansQ35848395
Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malariaQ35873505
Mannan-binding-lectin-associated serine proteases, characteristics and disease associationsQ36270453
A population-based study of morbidity and mortality in mannose-binding lectin deficiencyQ36399188
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced riskQ36402570
Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functionsQ36565247
Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteinsQ36927870
A role of macrophage complement receptor CRIg in immune clearance and inflammation.Q37254633
Degradome expression profiling in human articular cartilageQ37270886
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activationQ37382867
The complement system in systemic autoimmune diseaseQ37652141
Molecular defects in the mannose binding lectin pathway in dermatological disease: Case report and literature review.Q37718970
The genetics of ficolinsQ37726757
Specifically binding of L-ficolin to N-glycans of HCV envelope glycoproteins E1 and E2 leads to complement activationQ37728717
The lectin pathway and its implications in coagulation, infections and auto-immunityQ37819940
Mannose-binding lectin binds to two major outer membrane proteins, opacity protein and porin, of Neisseria meningitidis.Q37867614
Disease-causing mutations in genes of the complement systemQ37888153
Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?Q37989272
[Mannose-binding lectin gene site mutations and the susceptibility of rheumatic heart disease]Q54638889
Assignment 1 of the gene encoding mannan-binding lectin-associated serine protease 2 (MASP2) to human chromosome 1p36.3→p36.2 by in situ hybridization and somatic cell hybrid analysisQ57631380
Low clinical penetrance of mannose-binding lectin–associated serine protease 2 deficiencyQ58840837
Stable bronchiectasis is associated with low serum L-ficolin concentrationsQ61946549
Association between lectin complement pathway initiators, C-reactive protein and left ventricular remodeling in myocardial infarction—A magnetic resonance studyQ63728000
Variation in FCN1 affects biosynthesis of ficolin-1 and is associated with outcome of systemic inflammationQ63728017
The FicolinsQ63728045
Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen)Q63728053
Association of mannose-binding-lectin deficiency with severe atherosclerosisQ63728133
Pre- and postoperative levels in serum of mannan-binding lectin associated serine protease-2 —a prognostic marker in colorectal cancerQ63753489
Biological Variation in Circulating Levels of Mannan-Binding Lectin (MBL) and MBL-Associated Serine Protease-2 and the Influence of Age, Gender and Physical ExerciseQ63753498
Characterization of the initial C3 convertase of the alternative pathway of human complement.Q64902892
Molecular basis of opsonic defect in immunodeficient childrenQ68303831
Age-dependent variation in the serum concentration of mannan-binding proteinQ71668573
Mannose binding protein (MBP) enhances mononuclear phagocyte function via a receptor that contains the 126,000 Mr component of the Clq receptorQ71800454
Oligomeric Structures Required for Complement Activation of Serum Mannan- Binding ProteinsQ71869104
Perinatal changes in serum mannose-binding protein (MBP) levelsQ72286605
Human L-ficolin: plasma levels, sugar specificity, and assignment of its lectin activity to the fibrinogen-like (FBG) domainQ74480915
Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarctionQ79255657
The mannan-binding lectin pathway and lung disease in cystic fibrosis--disfunction of mannan-binding lectin-associated serine protease 2 (MASP-2) may be a major modifierQ79257224
Two factors of the lectin pathway of complement, l-ficolin and mannan-binding lectin, and their associations with prematurity, low birthweight and infections in a large cohort of Polish neonatesQ79702427
Mannan-binding lectin plasma levels in leprosy: deficiency confers protection against the lepromatous but not the tuberculoid formsQ80109537
Sequence analysis of the mannose-binding lectin (MBL2) gene reveals a high degree of heterozygosity with evidence of selectionQ80442215
Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cellsQ80475635
Mannose-binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injuryQ81880380
Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitisQ82034898
Polymorphisms in the mannose-binding lectin gene as determinants of age-defined risk of coronary artery lesions in Kawasaki diseaseQ82132661
The mannan-binding lectin (MBL) pathway of complement activation: biochemistry, biology and clinical implicationsQ82210722
M-ficolin levels are associated with the occurrence of severe infections in patients with haematological cancer undergoing chemotherapyQ83210102
Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancerQ83995289
Involvement of lectin pathway activation in the complement killing of Giardia intestinalisQ84036147
Multiple routes of complement activation by Mycobacterium bovis BCGQ84448113
P304page(s)148
P577publication date2014-01-01
P1433published inFrontiers in pediatricsQ27725038
P1476titleThe lectin pathway of complement and rheumatic heart disease
P478volume2

Reverse relations

cites work (P2860)
Q91672533Association of ficolin-2 (FCN2) functional polymorphisms and protein levels with rheumatic fever and rheumatic heart disease: relationship with cardiac function
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