If there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it?

scientific article published on May 2014

If there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CEI.12241
P932PMC publication ID3992028
P698PubMed publication ID24255984
P5875ResearchGate publication ID258821866

P50authorDamon P EisenQ56751391
P2093author name stringM Osthoff
P2860cites workMannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus.Q54710071
Balancing selection is the main force shaping the evolution of innate immunity genesQ57755879
Genetically Determined Serum Levels of Mannose-Binding Lectin Correlate Negatively with Common Carotid Intima-Media Thickness in Systemic Lupus ErythematosusQ63728031
Mortality and Predictors of Mortality in Rheumatoid Arthritis — A Role for Mannose-binding Lectin?Q63728035
Double role of mannose-binding lectin in relation to carotid intima–media thickness in patients with rheumatoid arthritisQ63728039
Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with ischemic heart disease in rheumatoid arthritisQ63728063
The differing roles of the classical and mannose-binding lectin complement pathways in the events following skeletal muscle ischemia-reperfusionQ79370206
Genetically determined mannan-binding lectin deficiency is of minor importance in determining susceptibility to severe infections and vascular organ damage in systemic lupus erythematosusQ80171466
Sequence analysis of the mannose-binding lectin (MBL2) gene reveals a high degree of heterozygosity with evidence of selectionQ80442215
Low mannose-binding lectin (MBL) levels in neonates with pneumonia and sepsisQ80824122
Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factorsQ81300622
Cardiovascular death in rheumatoid arthritis: a population-based studyQ81484761
Mannose-binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injuryQ81880380
Mannose-binding lectin polymorphisms in clinical tuberculosisQ28203157
A human genome diversity cell line panelQ28214742
The 'involution' of mannose-binding lectinQ28268484
Mannose-binding lectin deficiency is associated with smaller infarction size and favorable outcome in ischemic stroke patientsQ28743387
Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human strokeQ33530136
Phylogenetic nomenclature and evolution of mannose-binding lectin (MBL2) haplotypesQ33577516
Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritisQ33686973
Variant G57E of Mannose Binding Lectin Associated with Protection against Tuberculosis Caused by Mycobacterium africanum but not by M. tuberculosisQ33939617
Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosusQ34098573
Mannose-binding lectin gene polymorphisms are associated with major infection following allogeneic hemopoietic stem cell transplantation.Q34621964
Young children's probability of dying before and after their mother's death: a rural South African population-based surveillance studyQ34649400
Evolution of the lectin-complement pathway and its role in innate immunityQ34659139
Impact of mannose-binding lectin on susceptibility to infectious diseases.Q35582450
Mannose-binding lectin and its genetic variants.Q36361610
Accelerated atherosclerosis, immune response and autoimmune rheumatic diseasesQ36399112
The genome of Salmonella enterica serovar TyphiQ36854781
Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signatureQ37182685
Harmful molecular mechanisms in sepsisQ37273299
Mannose-binding lectin and susceptibility to tuberculosis: a meta-analysisQ37773386
Evolution of the mannose-binding lectin gene in primates.Q38335440
Characterization of the interaction between serum mannan-binding protein and nucleic acid ligandsQ38353807
Influence of functional deficiency of complement mannose-binding lectin on outcome of patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary interventionQ38376259
Diversity of the MBL2 gene in various Brazilian populations and the case of selection at the mannose-binding lectin locusQ38913652
Atherosclerosis across 4000 years of human history: the Horus study of four ancient populationsQ39522362
Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infectionQ40073077
Manifestations of coronary atherosclerosis in young trauma victims--an autopsy studyQ40827514
Mannose-binding lectin: the pluripotent molecule of the innate immune systemQ41265798
Variants of the mannose-binding lectin gene in the Benin population: heterozygosity for the p.G57E allele may confer a selective advantage. 2007.Q43053819
Increased incidence and severity of the systemic inflammatory response syndrome in patients deficient in mannose-binding lectinQ43725440
Evolutionary insights into the high worldwide prevalence of MBL2 deficiency allelesQ44096290
Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South AmericaQ48021769
Involvement of complement pathways in patients with bacterial septicemiaQ50076168
Genotypes of the mannan-binding lectin gene and susceptibility to visceral leishmaniasis and clinical complications.Q51920358
P433issue2
P304page(s)165-171
P577publication date2014-05-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleIf there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it?
P478volume176

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cites work (P2860)
Q48485355Editorial Commentary: Shall We Disregard Mannose-Binding Lectin Modification in the Future Because We Cannot Prevent Sepsis With This Molecule?
Q47660974Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD.
Q37835225Mannose-binding lectin and l-ficolin polymorphisms in patients with community-acquired pneumonia caused by intracellular pathogens.
Q38427670Parietal and intravascular innate mechanisms of vascular inflammation
Q34991781The lectin pathway of complement and rheumatic heart disease.
Q35590174Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface

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