Dynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure

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Dynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MRFMMM.2011.02.008
P932PMC publication ID3098609
P698PubMed publication ID21376742
P5875ResearchGate publication ID50287939

P2093author name stringIgor G Panyutin
Irina V Panyutin
Mykyta V Sokolov
Ronald D Neumann
P2860cites workRadiation effects on developmentQ22252925
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblastsQ24336806
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Genome-wide gene expression changes in normal human fibroblasts in response to low-LET gamma-radiation and high-LET-like 125IUdR exposuresQ38517219
Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiationQ39875156
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TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinomaQ39976292
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phaseQ40232134
Microarray analysis of differentially expressed genes after exposure of normal human fibroblasts to ionizing radiation from an external source and from DNA-incorporated iodine-125 radionuclideQ40250003
E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts.Q40325397
Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response.Q40465636
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses.Q40946010
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Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblastsQ46709852
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Transcript profiling during preimplantation mouse developmentQ50672706
Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells.Q50919370
[The radiation effects of low doses of irradiation on human embryos and fetuses]Q72098527
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Regulation of apoptosis and differentiation by p53 in human embryonic stem cellsQ79441696
Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblastsQ81504550
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Q24600230
The DNA-damage response in human biology and diseaseQ24606586
Significance analysis of microarrays applied to the ionizing radiation responseQ24606608
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblastsQ24629646
PUMA, a potent killer with or without p53Q24631776
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray dosesQ24677973
Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cellsQ24679386
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p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signalingQ28117922
Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2Q28205047
p21 is a universal inhibitor of cyclin kinasesQ28257305
p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expressionQ28300071
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray dataQ31109129
Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cellsQ33396804
Gene expression profiles in radiation workers occupationally exposed to ionizing radiation.Q33409388
Expression of pluripotency-associated genes in the surviving fraction of cultured human embryonic stem cells is not significantly affected by ionizing radiation.Q33747678
Radiation-induced bystander effects in cultured human stem cellsQ33769819
Survival responses of human embryonic stem cells to DNA damageQ34078474
Use and application of stem cells in toxicologyQ34304879
Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells.Q34458727
Human embryonic stem cell technologies and drug discoveryQ34960815
Repair of endogenous DNA damageQ35132488
Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cellsQ35915738
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cellsQ35924505
Development of gene expression signatures for practical radiation biodosimetryQ36782351
Parallel human genome analysis: microarray-based expression monitoring of 1000 genesQ36825305
gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communicationQ36946414
Human embryonic stem cells have enhanced repair of multiple forms of DNA damageQ36953410
Functional genomics in radiation biology: a gateway to cellular systems-level studiesQ36987027
Developmentally-poised chromatin of embryonic stem cellsQ36992175
Directing cancer cells to self-destruct with pro-apoptotic receptor agonistsQ37319386
Polo-like kinases mediate cell survival in mitochondrial dysfunctionQ37321107
P407language of work or nameEnglishQ1860
P921main subjecttranscriptomeQ252857
human embryonic stem cellQ59626782
P304page(s)40-48
P577publication date2011-03-03
P1433published inMutation ResearchQ6943732
P1476titleDynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure
P478volume709-710

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cites work (P2860)
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Q33944653High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.
Q36200201Human embryonic stem cell responses to ionizing radiation exposures: current state of knowledge and future challenges
Q37139081Lessons learned about human stem cell responses to ionizing radiation exposures: a long road still ahead of us.
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Q34925126No DNA damage response and negligible genome-wide transcriptional changes in human embryonic stem cells exposed to terahertz radiation
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Q34162661Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells

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