Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats.

scientific article

Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1742-7843.2010.00589.X
P932PMC publication ID3128812
P698PubMed publication ID22545970
P5875ResearchGate publication ID224869640

P50authorJohn R. FalckQ42055496
Bahar TunctanQ59275427
P2093author name stringKafait U Malik
Belma Korkmaz
C Kemal Buharalioglu
Seyhan Sahan-Firat
Tuba Cuez
P2860cites workAnalysis of nitrate, nitrite, and [15N]nitrate in biological fluidsQ29616817
P-450 metabolites of arachidonic acid in the control of cardiovascular functionQ29620578
A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in ratsQ33900988
Septic shock; current pathogenetic concepts from a clinical perspective.Q34398376
Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase. Formation and identification of novel endothelium-dependent vasoconstrictor metabolitesQ34428688
Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular systemQ34463893
Regulation of the expression of inducible nitric oxide synthase.Q35605774
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donorsQ36138113
Nitric oxide synthase inhibition in sepsis? Lessons learned from large-animal studiesQ36203883
Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymesQ36698125
Nitric oxide in shockQ36835542
A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats.Q37041257
Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production.Q37199203
Involvement of COX and NOS induction in the sympatho-activation during sepsisQ40577810
Nitric oxide contributes to 20-HETE-induced relaxation of pulmonary arteriesQ44138643
Cyclooxygenase-2 inhibition attenuates lipopolysaccharide-induced cardiovascular failure.Q44240436
20-HETE-induced contraction of small coronary arteries depends on the activation of Rho-kinaseQ44353853
Regulation of renal CYP4A expression and 20-HETE synthesis by nitric oxide in pregnant ratsQ44396063
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.Q44455934
Activation of the PGI(2)/IP system contributes to the development of circulatory failure in a rat model of endotoxic shock.Q44749320
Role of cyclooxygenase in ventricular effects of adrenomedullin: is adrenomedullin a double-edged sword in sepsis?Q44758290
Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase.Q45819815
Nitric oxide and vascular reactivity in sepsis.Q46428848
Indomethacin and alpha-tocopheral enhanced survival in endotoxic rats.Q46624295
Inhibition by nitric oxide of cytochrome P450 4A activity contributes to endotoxin-induced hypotension in rats.Q46804513
20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenaseQ48493776
Influence of indomethacin on the haemodynamic effects of lipopolysaccharide in rats.Q50754226
Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites.Q54277924
Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteriesQ57220836
Inhibition of 20-HETE production contributes to the vascular responses to nitric oxideQ57221409
20-hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteriesQ70781584
Characterization of inducible nitric oxide synthase expression in endotoxemic rat cardiac myocytes in vivo and following cytokine exposure in vitroQ70792024
20-HETE relaxes bovine coronary arteries through the release of prostacyclinQ74132575
Selective inhibition of cyclooxygenase-2 by NS-398 in endotoxin shock rats in vivoQ74155318
Inhibition of extracellular signal-regulated kinase (ERK1/2) activity reverses endotoxin-induced hypotension via decreased nitric oxide production in ratsQ80380690
P433issue5
P921main subjectendotoxinsQ319997
P304page(s)877-882
P577publication date2010-11-01
P1433published inBasic and Clinical Pharmacology and ToxicologyQ15724438
P1476titleContribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats
P478volume107

Reverse relations

cites work (P2860)
Q3503618920-Hydroxyeicosatetraenoic acid inhibits ATP-induced COX-2 expression via peroxisome proliferator activator receptor-α in vascular smooth muscle cells.
Q36952174An eicosanoid-centric view of atherothrombotic risk factors
Q47348893Bexarotene, a Selective RXRα Agonist, Reverses Hypotension Associated with Inflammation and Tissue Injury in a Rat Model of Septic Shock.
Q37138417Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock
Q41470940Liposomal co-delivered oleanolic acid attenuates doxorubicin-induced multi-organ toxicity in hepatocellular carcinoma
Q37174392NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite
Q35173157Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide
Q55399934Prostaglandins in the pathogenesis of kidney diseases.
Q90355869The renal vasodilatory effect of prostaglandins is ameliorated in isolated-perfused kidneys of endotoxemic mice

Search more.