Designing screens: how to make your hits a hit.

scientific article

Designing screens: how to make your hits a hit. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1024843331
P356DOI10.1038/NRD1063
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nrd1063
P698PubMed publication ID12669025

P2093author name stringMark Namchuk
W Patrick Walters
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Current trends in lead discovery: are we looking for the appropriate properties?Q57017035
A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databasesQ28140411
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysQ28145712
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsQ28842973
Finding the molecules to fuel chemogenomicsQ29543531
Drug-like properties and the causes of poor solubility and poor permeabilityQ30660926
Recognizing molecules with drug-like propertiesQ30741925
Molecular scaffold-based design and comparison of combinatorial libraries focused on the ATP-binding site of protein kinasesQ30836871
Property distribution of drug-related chemical databases.Q30855791
High throughput docking for library design and library prioritizationQ30984706
Simple selection criteria for drug-like chemical matterQ30990966
Molecular complexity and its impact on the probability of finding leads for drug discoveryQ30993107
Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferaseQ31001616
Can we learn to distinguish between "drug-like" and "nondrug-like" molecules?Q32032942
Computational methods to predict binding free energy in ligand-receptor complexesQ34369739
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Prediction of intestinal permeabilityQ34581541
P433issue4
P304page(s)259-266
P577publication date2003-04-01
P1433published inNature Reviews Drug DiscoveryQ45998
P1476titleDesigning screens: how to make your hits a hit.
P478volume2

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