review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0378-4274(02)00508-8 |
P698 | PubMed publication ID | 12676457 |
P2093 | author name string | László Virág | |
Pál Gergely | |||
Csaba Szabó | |||
Eva Szabó | |||
P2860 | cites work | Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death | Q28361255 |
Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation | Q28374864 | ||
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly | Q29547442 | ||
Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations | Q30449094 | ||
Unraveling peroxynitrite formation in biological systems. | Q31969110 | ||
Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure | Q32077774 | ||
Intracellular ATP, a switch in the decision between apoptosis and necrosis. | Q33533984 | ||
Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite | Q71126722 | ||
Peroxynitrite causes apoptosis in rat thymocytes | Q71560699 | ||
The reaction of ebselen with peroxynitrite | Q71790290 | ||
Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages | Q71876441 | ||
Involvement of mitogen-activated protein kinase in peroxynitrite-induced cell death of human neuroblastoma SH-SY5Y cells | Q72989176 | ||
Calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA in U937 cells exposed to tert-butylhydroperoxide: the role of arachidonic acid | Q73492238 | ||
Cytotoxicity of peroxynitrite in rat pancreatic acinar AR4-2J cells | Q73803446 | ||
The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B | Q73909444 | ||
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity | Q73929017 | ||
Nitric oxide synthase activity in mitochondria | Q74038500 | ||
Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells | Q74061127 | ||
Nitrotyrosine causes selective vascular endothelial dysfunction and DNA damage | Q74171059 | ||
Nitrosative stress-induced apoptosis through inhibition of NF-kappa B | Q74389223 | ||
Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease | Q74518169 | ||
The central executioners of apoptosis: caspases or mitochondria? | Q77135310 | ||
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation | Q77394071 | ||
Catalysis by nitric oxide synthase | Q77565785 | ||
Crucial role of apopain in the peroxynitrite-induced apoptotic DNA fragmentation | Q77741334 | ||
Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants | Q77752845 | ||
Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines | Q77794329 | ||
Contrasting effects of NO and peroxynitrites on HSP70 expression and apoptosis in human monocytes | Q33845106 | ||
Serine/threonine protein kinases and apoptosis. | Q33876765 | ||
Energy requirement for caspase activation and neuronal cell death | Q33891338 | ||
Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB. | Q33989830 | ||
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures | Q34032447 | ||
Apoptosis and nuclear factor-kappa B: a tale of association and dissociation | Q34047177 | ||
Nuclear factor-kappa B, cancer, and apoptosis | Q34047210 | ||
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors | Q34838585 | ||
Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure | Q35027134 | ||
Inhibition of poly(ADP-ribose) synthetase (PARS) and protection against peroxynitrite-induced cytotoxicity by zinc chelation | Q35028471 | ||
Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology | Q35933719 | ||
Inducible nitric oxide synthase: what difference does it make? | Q37374566 | ||
Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide | Q37653122 | ||
Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-kappa B DNA binding activity | Q38294793 | ||
NF-kappaB inhibition enhances peroxynitrite-induced enterocyte apoptosis | Q40717021 | ||
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity | Q40794071 | ||
Acidic fibroblast growth factor attenuates the cytotoxic effects of peroxynitrite in primary human osteoblast precursors | Q40818793 | ||
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death | Q40833345 | ||
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis. | Q40958763 | ||
Peroxynitrite modulates MnSOD gene expression in lung epithelial cells | Q41008236 | ||
Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase | Q41102929 | ||
Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis | Q41115305 | ||
Oxidative damage and tyrosine nitration from peroxynitrite | Q41129375 | ||
Melatonin is a scavenger of peroxynitrite | Q41140748 | ||
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger | Q41226484 | ||
The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death. | Q41739739 | ||
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts | Q41776599 | ||
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose | Q41827439 | ||
Peroxynitrite-mediated release of arachidonic acid from PC12 cells | Q41908682 | ||
Insulin-like growth factor-1 protects peroxynitrite-induced cell death by preventing cytochrome c-induced caspase-3 activation | Q42163956 | ||
Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. | Q42486524 | ||
BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death | Q42495204 | ||
Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. | Q42524190 | ||
Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes: potential involvement of G protein and phosphatidylinositol 3-kinase (PI3 kinase). | Q43557316 | ||
Free 3-nitrotyrosine causes striatal neurodegeneration in vivo. | Q43601893 | ||
Mechanisms of peroxynitrite decomposition catalyzed by FeTMPS, a bioactive sulfonated iron porphyrin | Q43616050 | ||
The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal | Q43683788 | ||
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells | Q43856044 | ||
Metabolic consequences of DNA damage: DNA damage induces alterations in glucose metabolism by activation of poly (ADP-ribose) polymerase | Q43884373 | ||
3-Morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: a critical role for p21(ras)-MAPK-p19(ARF) pathway | Q43915344 | ||
Genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells exposed to peroxynitrite generated from SIN-1. | Q43958649 | ||
Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury | Q43964601 | ||
Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite | Q44035300 | ||
Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress | Q44059857 | ||
Peroxynitrite scavenging activity of herb extracts | Q44060274 | ||
Mimosine prevents the death of glucose-deprived immunostimulated astrocytes by scavenging peroxynitrite | Q44060405 | ||
Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2. | Q47774902 | ||
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. | Q48615547 | ||
Essential role of the mitochondrial respiratory chain in peroxynitrite-induced strand scission of genomic DNA. | Q52585216 | ||
Nitric Oxide Is Generated on the Skin Surface by Reduction of Sweat Nitrate | Q56058206 | ||
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation | Q57204875 | ||
Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide | Q68255434 | ||
P921 | main subject | cytotoxicity | Q246181 |
P304 | page(s) | 113-124 | |
P577 | publication date | 2003-04-01 | |
P1433 | published in | Toxicology Letters | Q1796854 |
P1476 | title | Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention | |
P478 | volume | 140-141 |
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