Central proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models

scientific article

Central proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PLoSO...989229R
P356DOI10.1371/JOURNAL.PONE.0089229
P932PMC publication ID3930705
P698PubMed publication ID24586614
P5875ResearchGate publication ID260447779

P50authorIrene Cózar-CastellanoQ59315250
Margarita Jiménez-PalomaresQ83638064
Sara Molina-GilQ96140506
Oscar Ortiz-BarajasQ114336645
Monica Garcia-AllozaQ42243268
Juan Jose Ramos-RodriguezQ46687294
Alfonso Maria Lechuga-SanchoQ46687316
German PerdomoQ47504458
P2860cites workAssociation of diabetes mellitus and dementia: the Rotterdam Study.Q50989914
Hyperinsulinemia and risk of Alzheimer disease.Q51526824
GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloidQ81242039
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brainQ83396445
Early exposure to a high-fat diet has more drastic consequences on metabolism compared with exposure during adulthood in ratsQ83720231
Brain structure and obesityQ24644378
Therapeutic targets of brain insulin resistance in sporadic Alzheimer's diseaseQ27021700
Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expressionQ30453017
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetesQ33859600
Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome.Q34031315
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neuronsQ34083053
Increased hippocampal neurogenesis in Alzheimer's disease.Q34281877
Insulin metabolism and the risk of Alzheimer disease: the Rotterdam StudyQ34458197
FTY720 normalizes hyperglycemia by stimulating β-cell in vivo regeneration in db/db mice through regulation of cyclin D3 and p57(KIP2).Q35774014
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomersQ35858008
Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesisQ35960169
Insulin resistance in the nervous systemQ36084516
Metabolic and vascular determinants of impaired cognitive performance and abnormalities on brain magnetic resonance imaging in patients with type 2 diabetesQ36087568
Leptin action on nonneuronal cells in the CNS: potential clinical applicationsQ36124118
The insulin regulatory network in adult hippocampus and pancreatic endocrine systemQ36231289
Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's diseaseQ36577266
The adverse impact of type 2 diabetes on brain volume in heart failureQ36786697
Insulin and ghrelin: peripheral hormones modulating memory and hippocampal functionQ37006359
Impaired neurogenesis in adult type-2 diabetic ratsQ37114319
The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads convergedQ37280580
Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic miceQ37295166
Adult hippocampal neurogenesis in aging and Alzheimer's disease.Q37823486
Dementia, diabetes, Alzheimer's disease, and insulin resistance in the brain: progress, dilemmas, new opportunities, and a hypothesis to tackle intersecting epidemics.Q37845040
Insulin resistance in the brain: an old-age or new-age problem?Q38013489
Mechanisms of diabetic complications.Q38072902
Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signalingQ38297889
Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 miceQ39460000
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulinQ41882101
High-fat diet ameliorates neurological deficits caused by defective astrocyte lipid metabolismQ41933641
Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes.Q42668655
Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.Q42950655
Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's diseaseQ43207399
Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and diabetes mellitus type-2.Q43260001
Cortical neurogenesis in adult rats after transient middle cerebral artery occlusionQ43599424
Neuroprotective actions of leptin on central and peripheral neurons in vitro.Q43791966
Cerebral cortical thickness in patients with type 2 diabetesQ46177073
A high fat diet does not exacerbate CA1 injury and cognitive deficits following global ischemia in rats.Q46205478
Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice.Q46396191
Impaired proliferation of non-parenchymal cells participates in an impairment of liver regeneration in db/db miceQ46591524
Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 miceQ48380166
Long-term potentiation enhances neurogenesis in the adult dentate gyrus.Q48515412
Brain magnetic resonance imaging correlates of impaired cognition in patients with type 2 diabetesQ48603149
The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's diseaseQ48615135
Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.Q48616769
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
neurogenesisQ1456827
P304page(s)e89229
P577publication date2014-02-20
P1433published inPLOS OneQ564954
P1476titleCentral proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models
P478volume9