Breast cancer methylomes establish an epigenomic foundation for metastasis

scientific article

Breast cancer methylomes establish an epigenomic foundation for metastasis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCITRANSLMED.3001875
P932PMC publication ID3146366
P698PubMed publication ID21430268
P5875ResearchGate publication ID50831656

P50authorJoan Massagué SoléQ462775
Stephen B. BaylinQ28113000
Linda T VahdatQ40149511
Sevin TurcanQ42574772
Andreas RimnerQ52313562
Mary Ellen MoynahanQ57518016
Venkatraman E SeshanQ104745215
Larry NortonQ37644083
P2093author name stringFang Fang
Ronglai Shen
Adriana Heguy
Timothy A Chan
Qianxing Mo
Agnes Viale
Nita Ahuja
Andrew Kaufman
Luc G T Morris
Dilip Giri
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PIK3CA mutation associates with improved outcome in breast cancer.Q38420422
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Smad signaling is required to maintain epigenetic silencing during breast cancer progression.Q39750283
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Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesisQ57240066
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Colon cancer: it's CIN or CIMPQ82175754
The epigenomics of cancerQ28289975
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Genome remodelling in a basal-like breast cancer metastasis and xenograftQ28395637
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosisQ28472991
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesQ29547229
Genes that mediate breast cancer metastasis to lungQ29547479
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitionsQ29614512
Gene silencing in cancer in association with promoter hypermethylationQ29617274
Hypomethylation distinguishes genes of some human cancers from their normal counterpartsQ29619217
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancerQ29622925
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingQ33268624
Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patientsQ33540332
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.Q33649722
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancerQ33848195
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.Q33888431
Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancerQ34018681
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.Q34477787
Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumorsQ34573834
DNA methylation markers and early recurrence in stage I lung cancerQ34761286
Basal-like breast cancer displays distinct patterns of promoter methylationQ34982503
DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associationsQ35009790
Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancerQ35605804
Lung metastasis genes couple breast tumor size and metastatic spread.Q35800363
Molecular concepts analysis links tumors, pathways, mechanisms, and drugsQ35812701
High-throughput methylation profiling by MCA coupled to CpG island microarrayQ36004673
Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancerQ36059237
DNA methylation profiles of female steroid hormone-driven human malignancies.Q36566168
Genetic determinants of cancer metastasisQ36794312
The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancerQ37131378
Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylationQ37133978
Agglomerative epigenetic aberrations are a common event in human breast cancerQ37187180
DNA methylation as a biomarker in breast cancerQ37620392
P433issue75
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
P304page(s)75ra25
P577publication date2011-03-01
P1433published inScience Translational MedicineQ1573955
P1476titleBreast cancer methylomes establish an epigenomic foundation for metastasis
P478volume3

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