| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.2174/1568011033482378 |
| P698 | PubMed publication ID | 12769773 |
| P50 | author | Yves Pommier | Q28320644 |
| P2093 | author name string | Olivier Sordet | |
| Kurt W Kohn | |||
| Qasim A Khan | |||
| P433 | issue | 4 | |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 271-290 | |
| P577 | publication date | 2003-07-01 | |
| P1433 | published in | Anti-Cancer Agents in Medicinal Chemistry | Q15759240 |
| P1476 | title | Apoptosis induced by topoisomerase inhibitors | |
| P478 | volume | 3 |
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| Q36435596 | A sensitive high performance liquid chromatography assay for the quantification of doxorubicin associated with DNA in tumor and tissues |
| Q28476505 | An integrated Drosophila model system reveals unique properties for F14512, a novel polyamine-containing anticancer drug that targets topoisomerase II |
| Q33793023 | Anti-cancer agents in Saudi Arabian herbals revealed by automated high-content imaging |
| Q35743146 | Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks |
| Q24627367 | Bioflavonoids as poisons of human topoisomerase II alpha and II beta |
| Q45762535 | Biophysical studies of mutated K562 DNA (erythroleukemic cells) binding to adriamycin and daunomycin reveal that mutations induce structural changes influencing binding behavior |
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| Q36625228 | Current and future therapeutic approaches for metastatic pheochromocytoma and paraganglioma: focus on SDHB tumors |
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| Q36897343 | Digitoxin as an anticancer agent with selectivity for cancer cells: possible mechanisms involved |
| Q50425134 | Diphenyl ditelluride-induced cell cycle arrest and apoptosis: a relation with topoisomerase I inhibition |
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| Q39580025 | Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide |
| Q51754682 | Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death. |
| Q35088098 | Identification of differential protein expression associated with development of unstable human carotid plaques |
| Q36525254 | Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I |
| Q36164329 | Inhibitory Effect of the Noncamptothecin Topoisomerase I Inhibitor LMP-400 on Female Mice Models and Human Pheochromocytoma Cells |
| Q34909651 | Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage |
| Q36568915 | Iron chelators with topoisomerase-inhibitory activity and their anticancer applications |
| Q35900943 | JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells |
| Q36054324 | Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide |
| Q40084513 | MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine |
| Q36772203 | Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence |
| Q34565690 | Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides |
| Q35680769 | Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks |
| Q28538507 | Mutation induced conformational changes in genomic DNA from cancerous K562 cells influence drug-DNA binding modes |
| Q33944673 | Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate |
| Q34459467 | NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells |
| Q35221459 | Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot |
| Q58747369 | PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin |
| Q33197915 | Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21. |
| Q36088641 | Prazosin displays anticancer activity against human prostate cancers: targeting DNA and cell cycle |
| Q39996364 | Protein arginine (N)-methyl transferase 7 (PRMT7) as a potential target for the sensitization of tumor cells to camptothecins |
| Q33957966 | Quinone-induced enhancement of DNA cleavage by human topoisomerase IIalpha: adduction of cysteine residues 392 and 405. |
| Q28509174 | RPN2 gene confers docetaxel resistance in breast cancer |
| Q39900172 | RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes. |
| Q39271267 | Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons. |
| Q39435616 | Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II. |
| Q36557533 | Repair of topoisomerase I-mediated DNA damage |
| Q37312057 | Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha-/- mice. |
| Q39670514 | SMT-A07, a 3-(Indol-2-yl) indazole derivative, induces apoptosis of leukemia cells in vitro |
| Q37697041 | Site-specific DNA-doxorubicin conjugates display enhanced cytotoxicity to breast cancer cells. |
| Q37332317 | Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity. |
| Q36149725 | Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors. |
| Q28087343 | Target therapy in metastatic pheochromocytoma: current perspectives and controversies |
| Q36316672 | Targeted drug delivery to mammalian mitochondria in living cells |
| Q33746211 | The binding modes and binding affinities of epipodophyllotoxin derivatives with human topoisomerase IIα |
| Q46529657 | The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA 'degradesome'. |
| Q41717711 | The multifunctional polydnavirus TnBVANK1 protein: impact on host apoptotic pathway |
| Q29614976 | Topoisomerase I inhibitors: camptothecins and beyond |
| Q44922420 | Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis |
| Q33922870 | Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. |
| Q44880264 | Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis |
| Q36624125 | Topoisomerases of kinetoplastid parasites: why so fascinating? |
| Q36040744 | Toxicity of the topoisomerase I inhibitors |
| Q33875792 | Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2). |
| Q37323539 | Using 3'-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIalpha |
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