| scholarly article | Q13442814 |
| P2093 | author name string | Virginia M-Y Lee | |
| Vytas A Bankaitis | |||
| Christopher G Burd | |||
| James H Soper | |||
| Victoria Kehm | |||
| P2860 | cites work | Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity | Q24293089 |
| Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast | Q24561807 | ||
| Rab GDI: a solubilizing and recycling factor for rab9 protein | Q24622581 | ||
| Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p | Q24677799 | ||
| Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models | Q24683059 | ||
| Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions | Q26269963 | ||
| Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
| alpha-Synuclein locus triplication causes Parkinson's disease | Q27860533 | ||
| α-Synuclein in Lewy bodies | Q27860680 | ||
| Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein | Q27861056 | ||
| A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae | Q27930001 | ||
| An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes | Q27930206 | ||
| Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs | Q27930315 | ||
| Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone | Q27930871 | ||
| The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae | Q27931511 | ||
| A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family | Q27932348 | ||
| Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. | Q27932969 | ||
| Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p) | Q27933262 | ||
| The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis | Q27934654 | ||
| Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition | Q27934729 | ||
| Global mapping of the yeast genetic interaction network | Q27934987 | ||
| Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast | Q27935177 | ||
| Vps51p links the VFT complex to the SNARE Tlg1p | Q27935910 | ||
| Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae. | Q27936151 | ||
| Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p | Q27936497 | ||
| Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p | Q27936691 | ||
| Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p | Q27936869 | ||
| Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae | Q27938337 | ||
| An essential role for a phospholipid transfer protein in yeast Golgi function | Q27938456 | ||
| Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein | Q27938693 | ||
| Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. | Q27939089 | ||
| Isolation and characterization of SYS genes from yeast, multicopy suppressors of the functional loss of the transport GTPase Ypt6p | Q27939917 | ||
| Positive and negative regulation of a SNARE protein by control of intracellular localization | Q27940373 | ||
| Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments | Q28114324 | ||
| Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications | Q28131600 | ||
| Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein | Q28511573 | ||
| Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration | Q28587785 | ||
| Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system | Q28594502 | ||
| Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects | Q28776473 | ||
| The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
| AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease | Q29547175 | ||
| Alpha-synuclein locus duplication as a cause of familial Parkinson's disease | Q29614762 | ||
| Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes | Q29617606 | ||
| Rapid and reliable protein extraction from yeast | Q29617781 | ||
| The E46K mutation in alpha-synuclein increases amyloid fibril formation. | Q30349931 | ||
| Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice | Q30476254 | ||
| Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae | Q30481396 | ||
| Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p | Q30656982 | ||
| Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry | Q33303514 | ||
| The GRIP domain - a novel Golgi-targeting domain found in several coiled-coil proteins | Q33859182 | ||
| Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs | Q33881676 | ||
| A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. | Q33982546 | ||
| Synucleinopathies: clinical and pathological implications | Q34140347 | ||
| Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein | Q34281429 | ||
| The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system | Q34318718 | ||
| Identification of two distinct synucleins from human brain | Q34341909 | ||
| Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling | Q34375103 | ||
| Identification of proteins that interact with a protein of interest: applications of the yeast two-hybrid system | Q34437389 | ||
| Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy | Q34646732 | ||
| A snc1 endocytosis mutant: phenotypic analysis and suppression by overproduction of dihydrosphingosine phosphate lyase | Q34779841 | ||
| The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae | Q34784061 | ||
| Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis | Q35058315 | ||
| An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system | Q35949003 | ||
| The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function | Q36031499 | ||
| Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae | Q36255542 | ||
| The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis | Q36423369 | ||
| Ultrastructure of Lewy bodies in the stellate ganglion | Q39987734 | ||
| Dense core vesicles around the Lewy body in incidental Parkinson's disease: an electron microscopic study | Q40095790 | ||
| Isolation and biochemical characterization of organelles from the yeast, Saccharomyces cerevisiae | Q40465413 | ||
| alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease | Q41676981 | ||
| The 31-kDa polypeptide is an essential subunit of the vacuolar ATPase in Saccharomyces cerevisiae | Q42631021 | ||
| Yeast cells provide insight into alpha-synuclein biology and pathobiology | Q42988614 | ||
| Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease | Q44013447 | ||
| Conformational behavior of human alpha-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T. | Q44214168 | ||
| Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice. | Q44852323 | ||
| Role of alpha-synuclein in presynaptic dopamine recruitment. | Q45182545 | ||
| Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson | Q46478232 | ||
| A combinatorial code for the interaction of alpha-synuclein with membranes | Q46601588 | ||
| An early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism | Q48352469 | ||
| Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease | Q48353748 | ||
| Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. | Q48384247 | ||
| Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein | Q48581887 | ||
| Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. | Q52165843 | ||
| Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains | Q52921597 | ||
| Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast | Q57179731 | ||
| A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease | Q64796863 | ||
| Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro | Q64865343 | ||
| A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans | Q67222567 | ||
| Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein | Q73815124 | ||
| Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis | Q79362817 | ||
| A novel mechanism of interaction between alpha-synuclein and biological membranes | Q83952593 | ||
| P433 | issue | 3 | |
| P921 | main subject | Synuclein | Q24767155 |
| P304 | page(s) | 391-405 | |
| P577 | publication date | 2010-10-02 | |
| P1433 | published in | Journal of Molecular Neuroscience | Q15708870 |
| P1476 | title | Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis | |
| P478 | volume | 43 |
| Q42322220 | Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome |
| Q89619563 | Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles |
| Q26776209 | Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease |
| Q38101508 | Alpha-synuclein and intracellular trafficking: impact on the spreading of Parkinson's disease pathology. |
| Q34774324 | Alpha-synuclein function and dysfunction on cellular membranes |
| Q38028819 | Alpha-synuclein: from secretion to dysfunction and death |
| Q47301116 | Autophagy impairment in Parkinson's disease. |
| Q39097048 | Cell Biology and Pathophysiology of α-Synuclein |
| Q38036519 | Contribution of yeast models to neurodegeneration research |
| Q95841078 | Decreased Vacuolar Ca2+ Storage and Disrupted Vesicle Trafficking Underlie Alpha-Synuclein-Induced Ca2+ Dysregulation in S. cerevisiae |
| Q38041991 | Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson's disease: potential therapeutic targets? |
| Q35691076 | Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity |
| Q30607522 | Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes |
| Q34550197 | Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways |
| Q36072427 | Genome-wide association study of neocortical Lewy-related pathology |
| Q24317509 | Human α-synuclein modulates vesicle trafficking through its interaction with prenylated Rab acceptor protein 1 |
| Q36873680 | Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy |
| Q34073890 | Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein |
| Q38038561 | Lysosome-dependent pathways as a unifying theme in Parkinson's disease. |
| Q37210083 | Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model. |
| Q43752239 | Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice |
| Q91730805 | Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies |
| Q37179079 | Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour |
| Q37857950 | Rabs, SNAREs and α-synuclein — Membrane trafficking defects in synucleinopathies |
| Q41579661 | Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells. |
| Q46241023 | Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers |
| Q38672388 | The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion |
| Q61804251 | The Role of Lipids in Parkinson's Disease |
| Q47071750 | The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals |
| Q51284194 | The Transcellular Propagation and Intracellular Trafficking of α-Synuclein. |
| Q47217972 | The emerging role of Rab GTPases in the pathogenesis of Parkinson's disease |
| Q38489289 | Toward stem cell-based phenotypic screens for neurodegenerative diseases |
| Q42213761 | Traffic jams and the complex role of α-Synuclein aggregation in Parkinson disease |
| Q38341877 | Trafficking and degradation pathways in pathogenic conversion of prions and prion-like proteins in neurodegenerative diseases |
| Q34380191 | Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. |
| Q35102466 | α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding. |
| Q24300131 | α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner |
| Q38099072 | α‐Synuclein: The Long Distance Runner |
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