An early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism

scientific article published in January 1993

An early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00334457
P698PubMed publication ID8480516

P2093author name stringY Mizutani
M Yokochi
K Hayashida
S Oyanagi
P2860cites workIdiopathic Parkinson's disease and the Lewy body disordersQ39503766
Ultrastructure of Lewy bodies in the stellate ganglionQ39987734
Dense core vesicles around the Lewy body in incidental Parkinson's disease: an electron microscopic studyQ40095790
Colloid (hyaline) inclusion bodies in the central nervous system: their presence in the substantia nigra is diagnostic of Parkinson's diseaseQ48169432
The Lewy body in Parkinson's disease.Q48254020
Relationships between Lewy bodies and pale bodies in Parkinson's diseaseQ48600286
Depigmentation in the nerve cells of the substantia nigra and locus ceruleus in ParkinsonismQ48603493
Juvenile parkinsonism--some clinical, pharmacological, and neuropathological aspectsQ48697227
New pathologic observations in juvenile onset parkinsonism with dystoniaQ48710035
Juvenile parkinsonism: a case with first clinical manifestation at the age of six years and with neuropathological findings suggesting a new pathogenesis.Q48772736
Ultrastructural observations in ParkinsonismQ51160729
Neuronal inclusions of Parkinson's diseaseQ67914362
Atypical senile dementia with widespread Lewy type inclusion in the cerebral cortexQ72848189
P433issue4
P921main subjectsubstantia nigraQ753278
Parkinson's diseaseQ11085
autopsyQ41482
P304page(s)445-448
P577publication date1993-01-01
P1433published inActa NeuropathologicaQ343168
P1476titleAn early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism
P478volume85

Reverse relations

cites work (P2860)
Q34989985A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration
Q35138501Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis
Q30481396Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae
Q40262236Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress
Q36329444Autophagy and neuronal cell death in neurological disorders
Q90240136Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
Q64251001Dietary Macronutrient Management to Treat Mitochondrial Dysfunction in Parkinson's Disease
Q92576096Female Sex and Brain-Selective Estrogen Benefit α-Synuclein Tetramerization and the PD-like Motor Syndrome in 3K Transgenic Mice
Q30607522Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes
Q44195128Genetic epidemiology of Parkinson's disease
Q28287237Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies
Q22252807Intraneuronal dopamine-quinone synthesis: A review
Q34478663Lewy bodies
Q35840040Lewy-body formation is an aggresome-related process: a hypothesis
Q47801119Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells
Q34073890Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein
Q35412397Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?
Q64869820Orphan neurones and amine excess: the functional neuropathology of Parkinsonism and neuropsychiatric disease
Q50532472Pale neurites, premature α-synuclein aggregates with centripetal extension from axon collaterals.
Q92465171Parkinson's disease: proteinopathy or lipidopathy?
Q34995015Parkinson's genetics: molecular insights for the new millennium.
Q43940212Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
Q30479870Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.
Q34117600The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein.
Q37003482The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates
Q36423369The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis
Q89790112The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

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