The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer

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The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1078-0432.CCR-10-3265
P932PMC publication ID3152795
P698PubMed publication ID21339307

P2093author name stringXue Xiao
Gong Yang
Jinsong Liu
Xi Cheng
Xiaohua Wu
Imelda Mercado-Uribe
Xiang Du
Daniel G Rosen
Bin Chang
Paul Chiao
Guangzhi Liu
Fengxia Xue
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Addressing reported pro-apoptotic functions of NF-kappaB: targeted inhibition of canonical NF-kappaB enhances the apoptotic effects of doxorubicinQ28476078
Signal-induced degradation of I kappa B alpha requires site-specific ubiquitinationQ28615601
Nuclear factor-kappaB in cancer development and progressionQ29547879
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
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Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancerQ33387721
Control of apoptosis by Rel/NF-kappaB transcription factorsQ33797163
Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancerQ33862932
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesisQ34095143
Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancerQ34159472
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The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesisQ35133880
Nuclear factor-kappaB: the enemy withinQ35893620
NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosisQ35971557
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinomaQ37428076
Nuclear factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cellsQ38308753
Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.Q40396768
NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.Q40431585
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancerQ40438108
Inhibition of inhibitor of nuclear factor-kappaB phosphorylation increases the efficacy of paclitaxel in in vitro and in vivo ovarian cancer modelsQ40486780
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regressionQ40513415
Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.Q40527525
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.Q40571746
Inhibition of NFkappaB increases the efficacy of cisplatin in in vitro and in vivo ovarian cancer modelsQ40577628
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Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A.Q41573546
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signalingQ42475218
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IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell linesQ43830219
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.Q45982548
Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinomaQ46154672
CDK4 coexpression with Ras generates malignant human epidermal tumorigenesisQ46492957
ARF the integrator: linking NF-kappaB, p53 and checkpoint kinasesQ46560525
Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancerQ46681064
NF-kappaB signaling. Many roads lead to madrid.Q52601425
Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old mice.Q53382930
Role of chemotherapy for patients with recurrent platinum-resistant advanced epithelial ovarian cancer: A cost-effectiveness analysis.Q53615123
Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8.Q54033436
Role of NF-κB in p53-mediated programmed cell deathQ57248006
p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor SuppressorQ58287158
Inhibition of Rel/Nuclear Factor-kappaB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras- and p53-independent tumor developmentQ74463183
Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1Q79929599
X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimizationQ80980462
NF-kappaB is required for UV-induced JNK activation via induction of PKCdeltaQ82579230
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
ovarian cancerQ172341
P304page(s)2181-2194
P577publication date2011-02-21
P1433published inClinical Cancer ResearchQ332253
P1476titleThe biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer
P478volume17

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