review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Bruce R Troen | |
P2860 | cites work | The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation | Q22009927 |
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 | ||
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 | ||
RANK is essential for osteoclast and lymph node development | Q24598872 | ||
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 | ||
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families | Q28137631 | ||
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice | Q28140546 | ||
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src | Q28142620 | ||
Expression and localization of estrogen receptor-beta in murine and human bone | Q28144931 | ||
Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man | Q28248505 | ||
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency | Q28284581 | ||
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor | Q28285539 | ||
A nonsense mutation in the cathepsin K gene observed in a family with pycnodysostosis | Q28297820 | ||
Deflazacort increases osteoclast formation in mouse bone marrow culture and the ratio of RANKL/OPG mRNA expression in marrow stromal cells | Q28366694 | ||
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling | Q28513445 | ||
Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones | Q28579975 | ||
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
Estrogen modulation of osteoclast lysosomal enzyme secretion | Q72259946 | ||
Specific binding of estrogen to osteoclast surfaces | Q72412314 | ||
Demonstration of estrogen receptor mRNA in bone using in situ reverse-transcriptase polymerase chain reaction | Q73063008 | ||
Age-related decline in osteoprotegerin expression by human bone marrow cells cultured in three-dimensional collagen sponges | Q73458768 | ||
Effects of age on serum dehydroepiandrosterone sulfate, IGF-I, and IL-6 levels in women | Q73815609 | ||
Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture | Q73853199 | ||
Sex steroids and bone | Q74124341 | ||
Inhibition of bone resorption by 17beta-estradiol in human bone marrow cultures | Q74276885 | ||
Accelerated turnover of metaphyseal trabecular bone in mice overexpressing cathepsin K | Q74354073 | ||
Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells | Q74520565 | ||
Sex steroids, mice, and men: when androgens and estrogens get very close to each other | Q77833163 | ||
Age-related changes in bone turnover in men | Q77995353 | ||
Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice | Q28593712 | ||
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 | ||
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis | Q29619487 | ||
Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation | Q31717820 | ||
Osteoclasts secrete the chemotactic cytokine mim-1. | Q31939533 | ||
Receptor activator of nuclear factor-kappa b ligand activates nuclear factor-kappa b in osteoclast precursors | Q31958046 | ||
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors | Q32024958 | ||
Cathepsin K mRNA detection is restricted to osteoclasts during fetal mouse development | Q32066782 | ||
A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function | Q33542094 | ||
The actions and interactions of sex steroids and growth factors/cytokines on the skeleton | Q33668744 | ||
Cell biology of the osteoclast | Q33700885 | ||
Skeletal effects of estrogens | Q33757719 | ||
Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis. | Q33843319 | ||
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia | Q33853506 | ||
Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells | Q33854310 | ||
The effects of oestrogens on linear bone growth | Q33949996 | ||
Involutional osteoporosis | Q34181888 | ||
Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens | Q34368450 | ||
Effect of Testosterone and Estradiol in a Man with Aromatase Deficiency | Q34431437 | ||
A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. | Q34470260 | ||
Oestrogen, bones and men: when testosterone just isn't enough. | Q34592284 | ||
Regulatory mechanisms of osteoblast and osteoclast differentiation | Q34728971 | ||
Molecular genetics of too much bone | Q34915198 | ||
Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression | Q35169193 | ||
Human giant cell tumors of the bone (osteoclastomas) are estrogen target cells | Q35412006 | ||
Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells | Q36230062 | ||
Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts | Q36380532 | ||
Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD. | Q36736233 | ||
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice | Q36791739 | ||
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice | Q36978306 | ||
Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone | Q37217673 | ||
Avian osteoclasts as estrogen target cells | Q37557847 | ||
Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions. | Q38296222 | ||
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin | Q39116155 | ||
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis | Q39714931 | ||
Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis | Q40565765 | ||
Histamine stimulates production of osteoclast differentiation factor/receptor activator of nuclear factor-kappaB ligand by osteoblasts | Q40696407 | ||
IGF-I regulates osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo. | Q40706159 | ||
Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway | Q40740093 | ||
A novel interaction between thyroid hormones and 1,25(OH)(2)D(3) in osteoclast formation | Q40748154 | ||
Platelet-derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor | Q40754782 | ||
Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling | Q40756889 | ||
Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating fac | Q40770110 | ||
Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin | Q40837367 | ||
Activation of p38 mitogen-activated protein kinase is crucial in osteoclastogenesis induced by tumor necrosis factor | Q40838540 | ||
Cytokines and estrogen in bone: anti-osteoporotic effects | Q40900427 | ||
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells | Q40927574 | ||
Expression of estrogen receptor-alpha in cells of the osteoclastic lineage | Q40965478 | ||
Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells | Q41004339 | ||
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. | Q41121255 | ||
Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor | Q42139985 | ||
In vitro secretion of cytokines by human bone marrow: effects of age and estrogen status | Q42456627 | ||
Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation | Q42475736 | ||
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways | Q42494588 | ||
Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice | Q42519780 | ||
A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function | Q42811314 | ||
Mechanical strain effect on bone-resorbing activity and messenger RNA expressions of marker enzymes in isolated osteoclast culture | Q43584322 | ||
Macrophage colony-stimulating factor suppresses osteoblast formation | Q43667817 | ||
New insights into the regulation of cathepsin K gene expression by osteoprotegerin ligand | Q43667822 | ||
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse | Q43681246 | ||
Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate | Q43755553 | ||
Cathepsin K, osteoclastic resorption, and osteoporosis therapy | Q43755557 | ||
Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-alpha, IL-1, and RANKL. | Q43864464 | ||
Two different pathways for the maintenance of trabecular bone in adult male mice | Q43936237 | ||
Osteoclastogenic potential of bone marrow cells increases with age in elderly women with fracture | Q44151297 | ||
Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. | Q45713487 | ||
Expression of RANKL and OPG correlates with age-related bone loss in male C57BL/6 mice | Q46092958 | ||
Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study | Q46270750 | ||
The role of IL-6 type cytokines and their receptors in bone | Q47966730 | ||
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. | Q52192178 | ||
Osteoprotegerin and its ligand: a new paradigm for regulation of osteoclastogenesis and bone resorption. | Q53897603 | ||
Osteoclasts isolated from membranous bone in children exhibit nuclear estrogen and progesterone receptors. | Q54318356 | ||
Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization | Q57272396 | ||
Tumor necrosis factor-α mediates polymethylmethacrylate particle-induced NF-κB activation in osteoclast precursor cells | Q58085449 | ||
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling | Q58326943 | ||
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ | Q59064307 | ||
Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors | Q71119891 | ||
Mammalian mature osteoclasts as estrogen target cells | Q71209943 | ||
Age-related bone loss in mice is associated with an increased osteoclast progenitor pool | Q72045416 | ||
Osteoclast synthesis and secretion and activation of latent transforming growth factor beta | Q72058811 | ||
P433 | issue | 6 | |
P304 | page(s) | 605-614 | |
P577 | publication date | 2003-06-01 | |
P1433 | published in | Experimental Gerontology | Q15766996 |
P1476 | title | Molecular mechanisms underlying osteoclast formation and activation | |
P478 | volume | 38 |
Q46282244 | Abnormal differentiation of dental pulp cells in cleidocranial dysplasia |
Q34426918 | Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells |
Q38711081 | Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functions |
Q25257354 | An overlooked connection: serotonergic mediation of estrogen-related physiology and pathology |
Q34302274 | Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption |
Q36021020 | Antiosteoporotic activity of phytoestrogen-rich fraction separated from ethanol extract of aerial parts of Cissus quadrangularis in ovariectomized rats |
Q81217157 | Association of depressive symptoms with bone mineral density in older men: a population-based study |
Q38995801 | BMP-2 and titanium particles synergistically activate osteoclast formation |
Q37777066 | Biological Factors Involved in Implant-Anchored Orthodontics and in Prosthetic-Implant Therapy: A Literature Review |
Q37982663 | Bisphosphonates: effects on osteoblast |
Q34613578 | Breast cancer metastasis to the bone: mechanisms of bone loss |
Q39533129 | Brief communication: the effects of disuse on the mechanical properties of bone: what unloading tells us about the adaptive nature of skeletal tissue |
Q28505691 | CD109 plays a role in osteoclastogenesis |
Q54641863 | Characterization of the cytokine pattern of porcine bone marrow-derived cells treated with 1alpha,25(OH)D. |
Q51220391 | Cyclical tensile force on periodontal ligament cells inhibits osteoclastogenesis through OPG induction. |
Q36610276 | Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. |
Q42776710 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting. |
Q80149413 | Effect of rhBMP-2 and osteogenic revulsants on proliferation and differentiation of bone marrow stromal cells in rats |
Q57779127 | Genetic Dissection of Human Stature in a Large Sample of Multiplex Pedigrees |
Q37304461 | HIV and Bone Disease: A Perspective of the Role of microRNAs in Bone Biology upon HIV Infection |
Q45419837 | Human cytomegalovirus, Epstein-Barr virus and bone resorption-inducing cytokines in periapical lesions of deciduous teeth |
Q35129179 | Inflammation and uncoupling as mechanisms of periodontal bone loss |
Q90087784 | Interleukin - 17 and Interleukin-10 as Inflammatory and Prevention Biomarkers in Periimplant Diseases |
Q51627247 | Modeling of bone adaptative behavior based on cells activities. |
Q91700438 | Myeloid-Derived Suppressor Cells at the Intersection of Inflammaging and Bone Fragility |
Q47710981 | Neuropeptide Y Y2 antagonist treated ovariectomized mice exhibit greater bone mineral density. |
Q39162234 | Osteoblasts subjected to mechanical strain inhibit osteoclastic differentiation and bone resorption in a co-culture system |
Q64071144 | Overview of RAW264.7 for osteoclastogensis study: Phenotype and stimuli |
Q28261795 | Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro |
Q38330138 | Reactive oxygen species stimulates receptor activator of NF-kappaB ligand expression in osteoblast |
Q39305575 | Reflections about Osteoarthritis and Curcuma longa |
Q39579627 | Retinoic acid inhibits NFATc1 expression and osteoclast differentiation |
Q37714909 | Small molecules for bone diseases |
Q39367467 | Storage media enhance osteoclastogenic potential of human periodontal ligament cells via RANKL-independent signaling. |
Q37596611 | Targeting subchondral bone for treating osteoarthritis: what is the evidence? |
Q36907683 | The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints |
Q28251189 | The regulation of cathepsin K gene expression |
Q81453343 | The role of dental pulp cells in resorption of deciduous teeth |
Q43164216 | Upregulation of osteopontin by osteocytes deprived of mechanical loading or oxygen |
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