Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc.

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Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc. is …
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scholarly articleQ13442814

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P356DOI10.1002/ART.30468
P8608Fatcat IDrelease_y6vqujqlifbrxepxq4hcoenm7i
P932PMC publication ID3166549
P698PubMed publication ID21618206
P5875ResearchGate publication ID51170550

P50authorAviva J SymesQ40014197
Laure RittiéQ54900363
P2093author name stringBernard Perbal
Irving M Shapiro
Makarand V Risbud
Harvey E Smith
Cassie M Tran
P2860cites workDegeneration of the intervertebral discQ21195247
CCN3 (NOV) interacts with connexin43 in C6 glioma cells: possible mechanism of connexin-mediated growth suppressionQ24297490
CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migrationQ24298699
The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathwayQ24298994
Functions and mechanisms of action of CCN matricellular proteinsQ24642303
The CCN family of proteins: structure-function relationshipsQ24658424
Potential cellular conformations of the CCN3(NOV) proteinQ24795317
N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecanQ28238572
Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulationQ28291719
CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal diseaseQ28568759
Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilageQ28571441
Proviral Rearrangements and Overexpression of a New Cellular Gene (nov) in Myeloblastosis-Associated Virus Type 1-Induced NephroblastomasQ31159804
Extracellular matrix in disc degenerationQ33238918
Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) geneQ33320699
Histology and pathology of the human intervertebral discQ34510523
Mechanobiology of the intervertebral disc and relevance to disc degenerationQ34510529
Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signalingQ34696270
Effects of TGF-beta1 and IGF-1 on proliferation of human nucleus pulposus cells in medium with different serum concentrationsQ35129618
CCN family proteins and angiogenesis: from embryo to adulthoodQ36675209
Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cellsQ37129591
CCN3 and bone marrow cells.Q37289872
Proteins on the catwalk: modelling the structural domains of the CCN family of proteinsQ37474542
Connective tissue growth factor: context-dependent functions and mechanisms of regulationQ37486405
New target genes for NOV/CCN3 in chondrocytes: TGF-beta2 and type X collagen.Q40350041
The expression of novH in adrenocortical cells is down-regulated by TGFbeta 1 through c-Jun in a Smad-independent mannerQ40714383
The Relation Between Sox9, TGF-beta1, and Proteoglycan in Human Intervertebral Disc CellsQ41608641
CCN3: Doctor Jekyll and Mister HydeQ42089546
Domain-specific CCN3 antibodies as unique tools for structural and functional studiesQ42737801
Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironmentQ46891204
Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy.Q51808840
P433issue10
P304page(s)3022-3031
P577publication date2011-10-01
P1433published inArthritis and RheumatismQ23929027
P1476titleTransforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc
P478volume63