| scholarly article | Q13442814 |
| P2093 | author name string | Dessislava Markova | |
| Irving M Shapiro | |||
| D Greg Anderson | |||
| Makarand V Risbud | |||
| Harvey E Smith | |||
| Aviva Symes | |||
| Bala Susarla | |||
| Cassie M Tran | |||
| Ravi Kumar Ponnappan | |||
| P2860 | cites work | Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation | Q24290777 |
| Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation | Q24302554 | ||
| Functions and mechanisms of action of CCN matricellular proteins | Q24642303 | ||
| Mechanisms of TGF-beta signaling from cell membrane to the nucleus | Q27860785 | ||
| The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling | Q28243202 | ||
| Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis | Q28252815 | ||
| Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc | Q28280742 | ||
| Extracellular matrix in disc degeneration | Q33238918 | ||
| Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice | Q33290573 | ||
| Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis | Q34105198 | ||
| Mechanobiology of the intervertebral disc and relevance to disc degeneration | Q34510529 | ||
| Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61). | Q34534934 | ||
| Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. | Q34610548 | ||
| CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes | Q36496112 | ||
| Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta | Q36663630 | ||
| CCN family proteins and angiogenesis: from embryo to adulthood | Q36675209 | ||
| SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc | Q37197284 | ||
| Proteins on the catwalk: modelling the structural domains of the CCN family of proteins | Q37474542 | ||
| Connective tissue growth factor: context-dependent functions and mechanisms of regulation | Q37486405 | ||
| Hypoxic induction of Ctgf is directly mediated by Hif-1. | Q38337618 | ||
| Comparison of growth factor and cytokine expression in patients with degenerated disc disease and herniated nucleus pulposus. | Q38493940 | ||
| Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells | Q40583180 | ||
| Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts | Q41700398 | ||
| Connective tissue growth factor (CTGF) promotes activated mesangial cell survival via up-regulation of mitogen-activated protein kinase phosphatase-1 (MKP-1). | Q41824997 | ||
| Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts | Q42805569 | ||
| Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosis | Q42833987 | ||
| The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation | Q43173820 | ||
| Expression and role of connective tissue growth factor in painful disc fibrosis and degeneration | Q44046024 | ||
| Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 | ||
| Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis | Q47578416 | ||
| Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. | Q50644695 | ||
| Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes. | Q51099346 | ||
| Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. | Q51808840 | ||
| Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts. | Q53594263 | ||
| Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites | Q81515834 | ||
| Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc | Q82735380 | ||
| P433 | issue | 7 | |
| P921 | main subject | connective tissue | Q25615 |
| P304 | page(s) | 1983-1992 | |
| P577 | publication date | 2010-07-01 | |
| P1433 | published in | Arthritis & Rheumatology | Q4797636 |
| P1476 | title | Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling | |
| P478 | volume | 62 |
| Q52615758 | A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis. |
| Q33557188 | Ageing in the musculoskeletal system |
| Q41353200 | Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor β-independent mechanism |
| Q58795684 | CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt-β-catenin signaling in nucleus pulposus cells |
| Q37635765 | CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration |
| Q90431486 | Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging |
| Q36455833 | Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder |
| Q46387742 | Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis |
| Q36544996 | Degenerative grade affects the responses of human nucleus pulposus cells to link-N, CTGF, and TGFβ3. |
| Q28390520 | Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics |
| Q26783031 | Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration |
| Q38651479 | Effects of CCN3 on rat cartilage endplate chondrocytes cultured under serum deprivation in vitro |
| Q35490110 | Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc model |
| Q89846141 | HIF-hypoxia signaling in skeletal muscle physiology and fibrosis |
| Q39475834 | Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease |
| Q36812375 | Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity |
| Q33275485 | Investigating microenvironmental regulation of human chordoma cell behaviour |
| Q92313281 | Ligustrazine Prevents Intervertebral Disc Degeneration via Suppression of Aberrant TGFβ Activation in Nucleus Pulposus Cells |
| Q42314948 | Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis |
| Q90653505 | Mechanotransduction and cell biomechanics of the intervertebral disc |
| Q37728750 | Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus |
| Q38097283 | Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues |
| Q59136098 | NTG-101: A Novel Molecular Therapy that Halts the Progression of Degenerative Disc Disease |
| Q55354005 | Nogo-C regulates post myocardial infarction fibrosis through the interaction with ER Ca2+ leakage channel Sec61α in mouse hearts. |
| Q58800992 | Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage? |
| Q39660878 | Parathyroid hormone-potentiated connective tissue growth factor expression in human renal proximal tubular cells through activating the MAPK and NF- B signalling pathways |
| Q51575900 | Regulation of a disintegrins and metalloproteinase with thrombospondin motifs 7 during inflammation in nucleus pulposus (NP) cells: role of AP-1, Sp1 and NF-κB signaling. |
| Q37111035 | SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc. |
| Q42507600 | Smad3 controls β-1,3-glucuronosyltransferase 1 expression in rat nucleus pulposus cells: implications of dysregulated expression in disc disease |
| Q35587148 | TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways. |
| Q39521876 | TGFβ regulates Galectin-3 expression through canonical Smad3 signaling pathway in nucleus pulposus cells: implications in intervertebral disc degeneration |
| Q35195070 | Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc. |
| Q52727962 | Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling. |
| Q35008504 | Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3. |
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