| P2093 | author name string | Irving M Shapiro | |
| | Makarand V Risbud | |
| | Cassie M Tran | |
| P2860 | cites work | CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1 | Q24303627 |
| | Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development | Q24616861 |
| | The role of CCN2 in cartilage and bone development | Q24627602 |
| | Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation | Q24649542 |
| | Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this? | Q26995748 |
| | Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model | Q28142724 |
| | Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan | Q28235118 |
| | N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan | Q28238572 |
| | Roles for CCN2 in normal physiological processes | Q28246114 |
| | Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis | Q28252815 |
| | Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets | Q28254386 |
| | Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene | Q28263327 |
| | Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis | Q28275409 |
| | CCN2 is required for bleomycin‐induced skin fibrosis in mice | Q28295283 |
| | Uptake and intracellular transport of the connective tissue growth factor: a potential mode of action | Q28355056 |
| | Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage | Q28571441 |
| | Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc | Q28582270 |
| | Expression and roles of connective tissue growth factor in Meckel's cartilage development | Q28593647 |
| | Ets-1 is essential for connective tissue growth factor (CTGF/CCN2) induction by TGF-β1 in osteoblasts | Q31059602 |
| | Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor | Q33537427 |
| | CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network | Q33961583 |
| | Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis | Q34105198 |
| | Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin | Q34107237 |
| | Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes. | Q34343807 |
| | Structure and function of the notochord: an essential organ for chordate development | Q34418493 |
| | Histology and pathology of the human intervertebral disc | Q34510523 |
| | CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins | Q34537740 |
| | PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc | Q34589291 |
| | Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling | Q34696270 |
| | Temporal and spatial expression of CCN genes in zebrafish | Q35097480 |
| | Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc. | Q35195070 |
| | HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc | Q35678327 |
| | A novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells | Q35760478 |
| | CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes | Q36496112 |
| | Degenerative grade affects the responses of human nucleus pulposus cells to link-N, CTGF, and TGFβ3. | Q36544996 |
| | Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta | Q36663630 |
| | CCN family proteins and angiogenesis: from embryo to adulthood | Q36675209 |
| | Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts | Q36724904 |
| | Role of CCN2/CTGF/Hcs24 in bone growth | Q36729090 |
| | Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression | Q36754492 |
| | Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord | Q36790063 |
| | Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity | Q36812375 |
| | Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma | Q37093118 |
| | Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes | Q37331302 |
| | CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition | Q37384251 |
| | Proteins on the catwalk: modelling the structural domains of the CCN family of proteins | Q37474542 |
| | Connective tissue growth factor: context-dependent functions and mechanisms of regulation | Q37486405 |
| | Hypoxic regulation of nucleus pulposus cell survival: from niche to notch | Q37687706 |
| | The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region | Q38310076 |
| | Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation | Q38313230 |
| | Hypoxic induction of Ctgf is directly mediated by Hif-1. | Q38337618 |
| | Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex | Q38342104 |
| | A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene | Q38359426 |
| | Role of LRP1 in transport of CCN2 protein in chondrocytes. | Q39372835 |
| | Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA. | Q39607818 |
| | Src is a major signaling component for CTGF induction by TGF-beta1 in osteoblasts | Q39708889 |
| | Intrinsic biological activity of the thrombospondin structural homology repeat in connective tissue growth factor | Q40307774 |
| | Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3'-untranslated region interacting with a cellular protein in human chondrosarcoma cells. | Q40358322 |
| | Connective tissue growth factor as a major angiogenic agent that is induced by hypoxia in a human breast cancer cell line | Q40772926 |
| | Regulatory mechanism of human connective tissue growth factor (CTGF/Hcs24) gene expression in a human chondrocytic cell line, HCS-2/8. | Q40795597 |
| | The Relation Between Sox9, TGF-beta1, and Proteoglycan in Human Intervertebral Disc Cells | Q41608641 |
| | The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts | Q41766529 |
| | Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc | Q41781376 |
| | Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1α degradation | Q41821171 |
| | The induction of CCN2 by TGFbeta1 involves Ets-1. | Q41849541 |
| | CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes | Q42013999 |
| | Functional requirement of CCN2 for intramembranous bone formation in embryonic mice | Q42155503 |
| | Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK. | Q42459183 |
| | CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling | Q42498294 |
| | CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. | Q42526004 |
| | Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia | Q43209162 |
| | Expression and role of connective tissue growth factor in painful disc fibrosis and degeneration | Q44046024 |
| | Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen | Q44644827 |
| | Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). | Q44961475 |
| | Hypoxia interferes with connective tissue growth factor (CTGF) gene expression in human proximal tubular cell lines. | Q45956372 |
| | Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases | Q46433518 |
| | Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat. | Q46829108 |
| | Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts. | Q46873529 |
| | Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 |
| | Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid | Q46990448 |
| | Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells | Q47415775 |
| | Evidence for skeletal progenitor cells in the degenerate human intervertebral disc. | Q50872079 |
| | Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes. | Q51099346 |
| | Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts. | Q53594263 |
| | Differential roles of CCN family proteins during osteoblast differentiation: Involvement of Smad and MAPK signaling pathways. | Q54359166 |
| | Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes. | Q54517770 |
| | Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration | Q61699186 |
| | Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage | Q64377854 |
| | MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP | Q79981860 |
| | Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk | Q80177979 |
| | Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites | Q81515834 |
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lessons learned | Q1673259 |
| P304 | page(s) | 298-306 | |
| P577 | publication date | 2013-04-06 | |
| P1433 | published in | Matrix Biology | Q6787851 |
| P1476 | title | Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues | |
| P478 | volume | 32 | |