BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20141380
P932PMC publication ID4387288
P698PubMed publication ID25824819
P5875ResearchGate publication ID275253040

P50authorShane CrottyQ65508706
P2093author name stringAri Melnick
Marcella Bothwell
Elias K Haddad
Katerina Hatzi
J Philip Nance
Mark A Kroenke
P2860cites workGalaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciencesQ21092859
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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5Q24635387
The AP-1 transcription factor Batf controls T(H)17 differentiationQ24644525
A brief history of T cell help to B cellsQ26825185
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EBI2 mediates B cell segregation between the outer and centre follicleQ28251850
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiationQ28252247
Bcl6 mediates the development of T follicular helper cellsQ28252825
Kruppel-like factor 2 regulates thymocyte and T-cell migrationQ28253004
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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gammaQ28506783
Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiationQ28511315
Control of inflammation, cytokine expression, and germinal center formation by BCL-6Q28585541
A validated regulatory network for Th17 cell specificationQ28586624
Inhibition of Th2 differentiation and GATA-3 expression by BCL-6Q28594529
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Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell developmentQ33576343
In vivo regulation of Bcl6 and T follicular helper cell developmentQ33936471
An integrated ChIP-seq analysis platform with customizable workflowsQ33953905
In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiationQ34160642
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centersQ34175167
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Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes.Q34444243
An atlas of active enhancers across human cell types and tissuesQ34660689
The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cellsQ34901817
ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.Q35064898
ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.Q35101189
The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.Q35537706
Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell DifferentiationQ35884238
Fos/AP-1 proteins in bone and the immune systemQ36324940
STATs shape the active enhancer landscape of T cell populationsQ36431152
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanismsQ36703936
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.Q37636349
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responsesQ37718722
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesisQ38201872
T follicular helper cell differentiation, function, and roles in diseaseQ38264816
ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6Q42136332
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.Q50731194
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitmentQ50736370
GSEA-P: a desktop application for Gene Set Enrichment AnalysisQ51909999
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.Q55034216
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expressionQ79769520
Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responsesQ84250521
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
T follicular helper cellQ5464650
P304page(s)539-553
P577publication date2015-03-30
P1433published inJournal of Experimental MedicineQ3186912
P1476titleBCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
P478volume212

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