Expansion, selection and mutation of antigen-specific B cells in germinal centers

scientific article published on April 1, 1992

Expansion, selection and mutation of antigen-specific B cells in germinal centers is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1600-065X.1992.TB00630.X
P698PubMed publication ID1375924

P2093author name stringD. Gray
T. Leanderson
E. Källberg
P2860cites workBcl-2 maintains B cell memoryQ24308796
Most peripheral B cells in mice are ligand selectedQ33387224
The B-cell antigen receptor of the five immunoglobulin classesQ34835910
THE IMMUNOGLOBULINS OF MICE. V. THE METABOLIC (CATABOLIC) PROPERTIES OF FIVE IMMUNOGLOBULIN CLASSESQ36267537
STUDIES ON RABBIT LYMPHOCYTES IN VITRO. I. STIMULATION OF BLAST TRANSFORMATION WITH AN ANTIALLOTYPE SERUMQ36267713
Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouseQ36342237
Population kinetics of rat peripheral B cellsQ36354603
Developmentally regulated and strain-specific expression of murine VH gene familiesQ36355024
The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting?Q37953676
Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathwaysQ38624487
Intraclonal generation of antibody mutants in germinal centresQ41172275
Compartmentalization of MHC class II gene expression in transgenic miceQ41422626
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.Q41423746
The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chainQ41723817
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferationQ41964290
Kinetic maturation of an immune responseQ42018143
Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations.Q45980652
Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responsesQ48348065
A single rearrangement event generates most of the chicken immunoglobulin light chain diversityQ48381680
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversificationQ48397569
Molecular components of the B-cell antigen receptor complex of the IgM classQ50335807
B-cell memory is short-lived in the absence of antigen.Q52120670
Is rapid proliferation in B centroblasts linked to somatic mutation in memory B cell clones?Q52122457
IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice.Q54710076
Somatic mutation and the maturation of immune response to 2-phenyl oxazoloneQ58019387
Mechanism of antigen-driven selection in germinal centresQ59072211
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genesQ59098044
Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D regionQ69235085
P407language of work or nameEnglishQ1860
P304page(s)47-61
P577publication date1992-04-01
P1433published inImmunological ReviewsQ15724582
P1476titleExpansion, selection and mutation of antigen-specific B cells in germinal centers
P478volume126

Reverse relations

cites work (P2860)
Q34505084A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene.
Q52040361An antigen valence theory to explain the evolution and organization of the humoral immune response.
Q71877378Analysis of bcl-2+ lymphocyte subpopulations in inflammatory synovial infiltrates by a double-immunostaining technique
Q37162837Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.
Q34328629Analysis of somatic mutation in five B cell subsets of human tonsil
Q36361955Antigen-driven B cell differentiation in vivo
Q37770981Cellular choreography in the germinal center: new visions from in vivo imaging
Q70567411Cross-linking of surface IgM, but not surface IgD receptors, by soluble monoclonal antibodies primes murine B cells to secrete immunoglobulin in response to lymphokines
Q35851102Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines
Q41522446Differentiation and apoptosis of human germinal center B-lymphocytes
Q72753487Evidence for a stromal cell-dependent, self-renewing B cell population in lymphoid follicles of the ileal Peyer's patch of sheep
Q52058149Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell.
Q84199195Expression of IgA class switching gene in tonsillar mononuclear cells in patients with IgA nephropathy
Q39517304Follicular Dendritic Cells Initiate and Maintain Infection of the Germinal Centers by Human Immunodeficiency Virus
Q28294153Follicular dendritic cells and germinal centers
Q41649525Gamma delta T-cell help in responses to pathogens and in the development of systemic autoimmunity
Q39778902Germinal center B cells latently infected with Epstein-Barr virus proliferate extensively but do not increase in number
Q42114332Germinal center founder cells display propensity for apoptosis before onset of somatic mutation
Q54793851Immunobiology of chicken germinal center: I. Changes in surface Ig class expression in the chicken splenic germinal center after antigenic stimulation.
Q33887344Immunoglobulin production by cultured human lymphocytes
Q36362440In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells
Q73510662Increase in tonsillar germinal centre B-1 cell numbers in IgA nephropathy (IgAN) patients and reduced susceptibility to Fas-mediated apoptosis
Q42122378Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes
Q33897378Isolation of germinal centerlike events from human spleen RNA. Somatic hypermutation of a clonally related VH6DJH rearrangement expressed with IgM, IgG, and IgA
Q48078189Kinetics of somatic mutation in lymph node germinal centres
Q41200046Molecular characterization of an unusual non-Hodgkin's B-lymphoma cell line ("Farage") lacking the ability to produce immunoglobulin polypeptide chains
Q44870111Predicted and inferred waiting times for key mutations in the germinal centre reaction: evidence for stochasticity in selection
Q35554322Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome
Q36596432Telomere lengthening and telomerase activation during human B cell differentiation
Q35796008The Emu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strain
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Q41983676The intersection of Epstein-Barr virus with the germinal center
Q43548521Waiting times to appearance and dominance of advantageous mutants: estimation based on the likelihood

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