| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1146/ANNUREV.IY.07.040189.002541 |
| P698 | PubMed publication ID | 2653375 |
| P50 | author | Klaus Rajewsky | Q126992 |
| P2093 | author name string | Kocks C | |
| P921 | main subject | antibody | Q79460 |
| P304 | page(s) | 537-559 | |
| P577 | publication date | 1989-01-01 | |
| P1433 | published in | Annual Review of Immunology | Q567362 |
| P1476 | title | Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways | |
| P478 | volume | 7 |
| Q36295519 | A complementarity-determining region synthetic peptide acts as a miniantibody and neutralizes human immunodeficiency virus type 1 in vitro |
| Q42604824 | A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germ-line" natural antibody template. Analysis by V gene segment reassortment and site-directed mutagenesis |
| Q67690200 | A myeloma M104E private idiotope is represented predominantly among anti-dextran, peritoneal cavity Ly-1 precursor B cells |
| Q92550610 | A new look at IgE beyond allergies |
| Q34505084 | A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene. |
| Q44930027 | Abnormalities in peripheral B cell memory of patients with primary Sjögren's syndrome |
| Q48056149 | Accumulation of somatic hypermutation and antigen-driven selection in rapidly cycling surface Ig+ germinal center (GC) B cells which occupy GC at a high frequency during the primary anti-hapten response in mice |
| Q36366097 | Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen. |
| Q36361050 | Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen 1/intercellular adhesion molecule 1 and very late antigen 4/vascular cell adhesion molecule 1 pathways |
| Q36364275 | Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation |
| Q36786969 | An Evolutionarily-Conserved Role for Murine Ly-1 B Cells in Protection Against Bacterial Infections |
| Q36361955 | Antigen-driven B cell differentiation in vivo |
| Q46147419 | Antigen-induced B-cell death and elimination during germinal-centre immune responses |
| Q40806399 | B-1a, B-1b and B-2 B cells display unique VHDJH repertoires formed at different stages of ontogeny and under different selection pressures. |
| Q41225482 | B-cell activation by superstimulatory influenza virus hemagglutinin: a pathogenesis for autoimmunity? |
| Q52019514 | Both CD45R(low) and CD45R(high) "revertant" CD4 memory T cells provide help for memory B cells. |
| Q41828070 | Burkitt's lymphomas express VH genes with a moderate number of antigen-selected somatic mutations. |
| Q71930311 | CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus |
| Q36636718 | CD5+ B cells in autoimmune disease and lymphoid malignancy |
| Q28294678 | Cells in the marginal zone of the spleen |
| Q35533666 | Cellular and molecular mechanisms of B lymphocyte tolerance |
| Q36341119 | Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation |
| Q37120876 | Clonal evolution of a follicular lymphoma: evidence for antigen selection |
| Q37385073 | Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis. |
| Q41002744 | Clonal selection and learning in the antibody system |
| Q33501831 | Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization |
| Q35320786 | Cytokines mediating the proliferation and differentiation of B-1 lymphocytes and their role in ontogeny and phylogeny |
| Q42517634 | Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice |
| Q72087176 | Differential Sensitivity to Interleukins of CDS and CDS Anti-Dna Antibody-Producing B Cells in Murine Lupus |
| Q35851102 | Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines |
| Q40673767 | Differentiation of the secondary B-lymphocyte repertoire: the germinal center reaction |
| Q48049097 | Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression |
| Q72100138 | Direct Agglutination of Weak D Red Cells by Tetramolecular Complexes Containing Monoclonal IgG Anti‐D |
| Q52414521 | Dynamics and topology of idiotypic networks. |
| Q36214093 | Early and late B-cell development in the mouse |
| Q73689109 | Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation |
| Q35320490 | Expansion, selection and mutation of antigen-specific B cells in germinal centers |
| Q24682616 | Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease |
| Q24561494 | Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma |
| Q28255454 | From a dream to reality |
| Q37837345 | From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all. |
| Q35064049 | Functional differences between memory and naive CD8 T cells |
| Q28362341 | Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells |
| Q42996739 | Gastric mucosa as an additional extrahepatic localization of hepatitis C virus: viral detection in gastric low-grade lymphoma associated with autoimmune disease and in chronic gastritis. |
| Q40696086 | Generating the antibody repertoire in rabbit. |
| Q34051992 | Genetic aspects of inherent B-cell abnormalities associated with SLE and B-cell malignancy: lessons from New Zealand mouse models |
| Q34014473 | Genomic organization, molecular diversification, and evolution of antimicrobial peptide myticin-C genes in the mussel (Mytilus galloprovincialis). |
| Q52045271 | Germinal center B cells rescued from apoptosis by CD40 ligation or attachment to follicular dendritic cells, but not by engagement of surface immunoglobulin or adhesion receptors, become resistant to CD95-induced apoptosis. |
| Q53477055 | H-2z homozygous New Zealand mice as a model for B-cell chronic lymphocytic leukemia: elevated bcl-2 expression in CD5 B cells at premalignant and malignant stages. |
| Q36352642 | Heavy-chain class switch does not terminate somatic mutation |
| Q48155343 | High frequency of somatically mutated IgM molecules in the human adult blood B cell repertoire |
| Q41107295 | How adaptive antibodies facilitate the evolution of natural antibodies |
| Q42514540 | IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. |
| Q52048376 | Identification of a novel subpopulation of germinal center B cells characterized by expression of IgD and CD70. |
| Q24680746 | Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells |
| Q45859104 | Immunoglobulin VH and VK genes of the BALB/c anti-foot-and-mouth disease virus (01) VP1 response: Cloning, characterization and transgenic mice |
| Q48073283 | Immunoglobulin variable gene analysis of human autoantibodies reveals antigen-driven immune response to glutamate decarboxylase in type 1 diabetes mellitus |
| Q34114760 | Immunoglobulin variable region hypermutation in hybrids derived from a pre-B- and a myeloma cell line |
| Q30826654 | In situ analysis of the variable heavy chain gene of an IgM/IgG-expressing follicular lymphoma: evidence for interfollicular trafficking of tumor cells. |
| Q31142113 | In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library |
| Q36216492 | Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation |
| Q48004003 | Inherent properties of somatic hypermutation as revealed by human non-productive VH6 immunoglobulin rearrangements |
| Q52904710 | Insight into Burkitt's lymphoma from immunoglobulin variable region gene analysis. |
| Q42942120 | Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells |
| Q41172275 | Intraclonal generation of antibody mutants in germinal centres |
| Q51982625 | Joining-chain (J-chain) negative mice are B cell memory deficient. |
| Q68091654 | Limited number of immunoglobulin VH regions expressed in the mutant rabbit "Alicia" |
| Q44465948 | Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay |
| Q35320913 | Location and function of B-cell lineages |
| Q57198384 | Lymphocyte populations and immune responses in CD5-deficient mice |
| Q43470922 | Maintenance of B-cell memory by long-lived cells generated from proliferating precursors |
| Q52224328 | Maintenance of CD5+B Cells at an Early Developmental Stage by Interleukin-5: Evidence from Immunoglobulin Gene Usage in Interleukin-5 Transgenic Mice |
| Q36713251 | Maintenance of immunological memory: a role for CD5+ B cells? |
| Q44875747 | Major histocompatibility complex controls clonal proliferation of CD5+ B cells in H-2-congenic New Zealand mice: a model for B cell chronic lymphocytic leukemia and autoimmune disease |
| Q37624015 | Man-made antibodies |
| Q52055817 | Maternal immunization modulates the primary immune response to 2-phenyl-oxazolone in BALB/c mice. |
| Q35905551 | Memory B lymphocytes migrate to bone marrow in humans |
| Q44582186 | Memory in helper T cells of minor histocompatibility antigens, revealed in vivo by alloimmunizations in combination with Thy-1 antigen |
| Q33958359 | Modeling and optimization of populations subject to time-dependent mutation |
| Q48061721 | Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enh |
| Q48062586 | Molecular characterization of VDJ transcripts from a newborn piglet |
| Q52099258 | Molecular characterization of single memory B cells. |
| Q33387224 | Most peripheral B cells in mice are ligand selected |
| Q41083928 | Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication |
| Q36231698 | Natural occurrence and origin of somatically mutated memory B cells in mice |
| Q28587370 | Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice |
| Q34562262 | Oral priming with Salmonella Typhi vaccine strain CVD 909 followed by parenteral boost with the S. Typhi Vi capsular polysaccharide vaccine induces CD27+IgD-S. Typhi-specific IgA and IgG B memory cells in humans |
| Q39114604 | Pattern of usage and somatic hypermutation in the V(H)5 gene segments of a patient with asthma: implications for IgE. |
| Q33838611 | Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases |
| Q36563392 | Precursor B cells for autoantibody production in genomically Fas-intact autoimmune disease are not subject to Fas-mediated immune elimination |
| Q67545229 | Proliferation and differentiation of human CD5+ and CD5- B cell subsets activated through their antigen receptors or CD40 antigens |
| Q44830476 | Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1). |
| Q33860729 | Protein evolution on partially correlated landscapes |
| Q36365981 | Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice |
| Q74139589 | Role of BCR affinity in T cell dependent antibody responses in vivo |
| Q40373293 | Self-tolerance checkpoints in B lymphocyte development |
| Q36771498 | Sequence dependent hypermutation of the immunoglobulin heavy chain in cultured B cells. |
| Q33764048 | Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation |
| Q48094934 | Somatic diversification and affinity maturation of IgM and IgG anti-DNA antibodies in murine lupus. |
| Q36361238 | Somatic hypermutation of an immunoglobulin mu heavy chain transgene |
| Q35554322 | Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome |
| Q41697487 | Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus |
| Q41522864 | Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection. |
| Q35321772 | Surface markers, heavy chain sequences and B cell lineages |
| Q36228283 | T-independent type II immune responses generate memory B cells |
| Q35096789 | Targeting the proteome/epitome, implementation of subtractive immunization |
| Q43744211 | Testing the reverse transcriptase model of somatic mutation |
| Q36486837 | The dark side of activation-induced cytidine deaminase: relationship with leukemia and beyond |
| Q35050628 | The double helix and immunology |
| Q35380833 | The dynamics of T cell-dependent B cell responses in vivo |
| Q34461508 | The early history of B cells |
| Q42942101 | The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen |
| Q48119006 | The majority of human tonsillar CD5+ B cells express somatically mutated Vχ4 genes |
| Q36354168 | The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response |
| Q42459578 | The role of interleukin-5 (IL-5) in vivo: studies with IL-5 deficient mice |
| Q38685035 | The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets |
| Q72102073 | The thymus‐independent antigen α(1–3) dextran elicits proliferation of precursors for specific IgM antibody‐producing cells (memory cells), which are revealed by LPS stimulation in soft agar cultures and detected by immunoblot |
| Q40874465 | Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections |
| Q56891639 | Unrestricted usage of immunoglobulin heavy chain genes in B cells infiltrating the wall of atherosclerotic abdominal aortic aneurysms |
| Q48134631 | V kappa gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the V kappa locus and do not show somatic mutation |
| Q41489024 | VH and V kappa segment structure of anti-insulin IgG autoantibodies in patients with insulin-dependent diabetes mellitus. Evidence for somatic selection. |
| Q36404575 | Virus-induced maturation and activation of autoreactive memory B cells |
| Q41544908 | What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants? |
| Q30890412 | With the benefit of hindsight |
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