scholarly article | Q13442814 |
P2093 | author name string | T Manser | |
K A Vora | |||
P2860 | cites work | Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 |
Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten | Q27659808 | ||
Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold | Q33646218 | ||
Stepwise intraclonal maturation of antibody affinity through somatic hypermutation | Q33664973 | ||
Germ line variable regions that match hypermutated sequences in genes encoding murine anti-hapten antibodies | Q33960151 | ||
Protein evolution on rugged landscapes | Q34296709 | ||
Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse | Q34380142 | ||
The molecular and cellular basis of affinity maturation in the antibody response | Q35862643 | ||
Selection of B cell clones and memory B cells | Q36137566 | ||
Germinal centers and antibody production in bone marrow | Q36171770 | ||
Different epitope structures select distinct mutant forms of an antibody variable region for expression during the immune response | Q36229997 | ||
Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin | Q36261566 | ||
The mechanism of antigenic stimulation of primary and secondary clonal precursor cells | Q36271704 | ||
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions | Q36302303 | ||
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene | Q36354162 | ||
The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response | Q36354168 | ||
Evolution of antibody structure during the immune response. The differentiative potential of a single B lymphocyte | Q36356890 | ||
Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice | Q36357540 | ||
Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation | Q36361415 | ||
Antigen-driven B cell differentiation in vivo | Q36361955 | ||
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells | Q36362440 | ||
Sequencing heavy- and light-chain variable genes of single B-hybridoma cells by total enzymatic amplification | Q37156660 | ||
Somatic recombination of heavy chain variable region transgenes with the endogenous immunoglobulin heavy chain locus in mice | Q37275566 | ||
The evolution of B-cell clones | Q37928297 | ||
The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting? | Q37953676 | ||
Structural characterization of idiotopes by using antibody variants generated by site-directed mutagenesis | Q38340444 | ||
Structural characterization of H chain-associated idiotopes of anti-p-azophenylarsonate monoclonal antibodies | Q38340718 | ||
Recurrent somatic mutations in mouse antibodies to p-azophenylarsonate increase affinity for hapten | Q38345434 | ||
Might gene conversion be the mechanism of somatic hypermutation of mammalian immunoglobulin genes? | Q38622353 | ||
Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways | Q38624487 | ||
The dynamic nature of the antibody repertoire | Q39545231 | ||
Evolution of antibody variable region structure during the immune response | Q39658887 | ||
Mutation drift and repertoire shift in the maturation of the immune response | Q39658890 | ||
Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development. | Q39658899 | ||
Evolutionary and somatic selection of the antibody repertoire in the mouse. | Q39682090 | ||
Cell Selection by Antigen in the Immune Response | Q39985236 | ||
The immune response to a simple antigenic determinant | Q40048013 | ||
The maintenance and regulation of the humoral immune response: persisting antigen and the role of follicular antigen-binding dendritic cells as accessory cells | Q40300507 | ||
Differentiation of the secondary B-lymphocyte repertoire: the germinal center reaction | Q40673767 | ||
Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections | Q40874465 | ||
Intraclonal generation of antibody mutants in germinal centres | Q41172275 | ||
The amino acid residues at the VH-D-JH junctions affect the affinity of anti-p-azophenylarsonate antibodies | Q41263547 | ||
Somatic mutation and clonal expansion of B cells in an antigen-driven immune response. | Q41380981 | ||
Somatic generation of hybrid antibody H chain genes in transgenic mice via interchromosomal gene conversion | Q41497161 | ||
Limits on heavy chain junctional diversity contribute to the recurrence of an antibody variable region | Q41951245 | ||
The BALB/c secondary response to the Sb site of influenza virus hemagglutinin. Nonrandom silent mutation and unequal numbers of VH and Vk mutations | Q42812230 | ||
Germinal centers develop oligoclonally | Q43487651 | ||
Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens | Q43603650 | ||
Towards a general theory of adaptive walks on rugged landscapes | Q47593883 | ||
Maturation of the immune response in germinal centers | Q48194763 | ||
Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice | Q48348716 | ||
Influence of Clonal Selection on the Expression of Immunoglobulin Variable Region Genes | Q48384664 | ||
ANTIGENS IN IMMUNITY. IV. CELLULAR LOCALIZATION OF 125-I- AND 131-I-LABELLED FLAGELLA IN LYMPH NODES | Q50267219 | ||
Molecular characterization of single memory B cells. | Q52099258 | ||
Relationship of germinal centers in lymphoid tissue to immunologic memory. VI. Transfer of B cell memory with lymph node cells fractionated according to their receptors for peanut agglutinin. | Q52214183 | ||
Molecular events during maturation of the immune response to oxazolone | Q58019376 | ||
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone | Q58019387 | ||
mIgM:mIgD ratios on B cells: mean mIgD expression exceeds mIgM by 10-fold on most splenic B cells | Q70467070 | ||
Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera | Q71714526 | ||
Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation | Q72117602 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell differentiation | Q210861 |
P304 | page(s) | 271-281 | |
P577 | publication date | 1995-01-01 | |
P1433 | published in | Journal of Experimental Medicine | Q3186912 |
P1476 | title | Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation | |
P478 | volume | 181 |
Q36368499 | Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment |
Q42627701 | Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains |
Q73689109 | Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation |
Q41949877 | In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection. |
Q40983825 | Life and death in germinal centers (redux). |
Q73291744 | Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site |
Q28585021 | Severe attenuation of the B cell immune response in Msh2-deficient mice |
Q33959225 | Silent development of memory progenitor B cells |
Q30435791 | Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3. |
Q42743187 | Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells |
Q52039310 | The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment. |
Q36376764 | The transcriptional promoter regulates hypermutation of the antibody heavy chain locus |
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