Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

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Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1987PNAS...84.9150S
P356DOI10.1073/PNAS.84.24.9150
P932PMC publication ID299710
P698PubMed publication ID3480535
P5875ResearchGate publication ID19674877

P2093author name stringShlomchik MJ
Pisetsky DS
Weigert MG
Aucoin AH
P2860cites workAntigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNAQ71441558
Genetic studies of autoimmunity in New Zealand mice. III. Associations among anti-DNA antibodies, NTA, and renal disease in (NZB x NZW)F1 x NZW backcross miceQ72091589
Amino acid difference formula to help explain protein evolutionQ29614440
Antibodies to Native and Denatured Deoxyribonucleic Acid in Systemic Lupus Erythematosus*Q30501383
Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.Q33880007
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosusQ34224780
Origins of anti-DNA autoantibodiesQ34528072
Sequence-specific recognition of double helical nucleic acids by proteinsQ35987597
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusionsQ36302303
Splenic immunoglobulin-secreting cells and their regulation in autoimmune miceQ36343302
Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipidsQ36344641
Induction of murine autoimmune disease by chronic polyclonal B cell activationQ36347616
Idiotypic cross-reactions of monoclonal human lupus autoantibodiesQ36348083
Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cellsQ36352229
Inter- and intraclonal diversity in the antibody response to influenza hemagglutininQ36355399
Clusters of point mutations are found exclusively around rearranged antibody variable genesQ36593569
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificityQ37568701
Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosusQ37603341
Specificity analysis of monoclonal anti-DNA antibodies from B6-lpr/lpr miceQ38353792
Antibodies to DNA. A perspectiveQ39754022
Autoantibodies to Nuclear Antigens (ANA): Their Immunobiology and MedicineQ40104710
Detection of anti-dsDNA as diagnostic toolQ41121760
Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host diseaseQ41559247
Pathogenesis of immune complex glomerulonephritis of New Zealand miceQ44143288
Anti-DNA autoantibodies in (NZB X NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype.Q53774113
Murine monoclonal anti-DNA autoantibodies bind to endogenous bacteria.Q54794605
The role of clonal selection and somatic mutation in autoimmunityQ59082893
Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expressionQ59085816
Profiles of antinuclear antibodies in systemic rheumatic diseasesQ66879096
Role of the Sm antigen in the generation of anti-Sm autoantibodies in the SLE-prone MRL mouseQ69493132
IgG antinuclear antibodies with cross-reactive rheumatoid factor activityQ69665252
A simple enzyme-linked immunosorbent assay for antibodies to native DNAQ70168709
A high frequency idiotypic marker of anti-DNA autoantibodies in MRL-Ipr/Ipr miceQ70240153
Correlation between clinical activity of systemic lupus erythematosus and the amounts of DNA in DNA/anti-DNA antibody immune complexesQ70454790
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectautoantibodyQ785022
P304page(s)9150-9154
P577publication date1987-12-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStructure and function of anti-DNA autoantibodies derived from a single autoimmune mouse
P478volume84

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Q42015134The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales
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Q35744698The role of autoantigens in the induction and maintenance of autoimmunity
Q36230378The role of clonal selection in the pathogenesis of an autoreactive human B cell lymphoma
Q38062588The role of somatic hypermutation in the generation of pathogenic antibodies in SLE.
Q52210540The site and stage of anti-DNA B-cell deletion.
Q43910570True anti-anionic phospholipid immunoglobulin M antibodies can exert lupus anticoagulant activity
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Q33248975Two closely related ? variable region pseudogenes pose an evolutionary paradox
Q33552573Two distinct populations of H chain-edited B cells show differential surrogate L chain dependence
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Q41500871Unique site of autoantibody production in Fas-deficient mice
Q37297721Use of similar immunoglobulin VH gene segments by MALT lymphomas of the ocular adnexa
Q33491181V gene analysis of anti-cardiolipin antibodies from (NZW x BXSB) F1 mice.
Q41489024VH and V kappa segment structure of anti-insulin IgG autoantibodies in patients with insulin-dependent diabetes mellitus. Evidence for somatic selection.
Q58041799VH gene expression in hairy cell leukaemia
Q36687015VH genes of human autoantibodies
Q42800186Variable region genes of anti-histone autoantibodies from a MRL/Mp-lpr/lpr mouse
Q48113515Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus
Q42800290Variable region sequences of pathogenic anti-mouse red blood cell autoantibodies from autoimmune NZB mice

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