CD44 and HCELL: preventing hematogenous metastasis at step 1.

scientific article

CD44 and HCELL: preventing hematogenous metastasis at step 1. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2011.07.039
P932PMC publication ID3195965
P698PubMed publication ID21827751
P5875ResearchGate publication ID51558076

P2093author name stringRobert Sackstein
Pieter P Jacobs
P2860cites workEndothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectinsQ24292943
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasisQ24529958
Identification of leukocyte E-selectin ligands, P-selectin glycoprotein ligand-1 and E-selectin ligand-1, on human metastatic prostate tumor cellsQ24546102
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic nicheQ24600542
SelectinsQ24602099
Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasisQ24630993
Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flowQ24644116
Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cellsQ24653465
Phenotypic characterization of human colorectal cancer stem cellsQ24674126
Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cellsQ24677693
CD44 is a major E-selectin ligand on human hematopoietic progenitor cellsQ24679247
Prospective identification of tumorigenic breast cancer cellsQ24683474
Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1Q27628438
Cancer-related inflammationQ27860907
Immunity, Inflammation, and CancerQ27861048
A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activityQ28140610
Two subsets of memory T lymphocytes with distinct homing potentials and effector functionsQ28146072
CD44: from adhesion molecules to signalling regulatorsQ28201701
CD44 in cancerQ28217782
Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140Q28237622
Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophagesQ28249582
Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migrationQ28251644
CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activityQ28259804
Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesisQ28260742
CD44 is the principal cell surface receptor for hyaluronateQ28261336
Death receptor-3, a new E-Selectin counter-receptor that confers migration and survival advantages to colon carcinoma cells by triggering p38 and ERK MAPK activationQ28264303
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to boneQ28264546
The dual role of CD44 as a functional P-selectin ligand and fibrin receptor in colon carcinoma cell adhesionQ28266614
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasisQ28275735
Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cellsQ28286650
Mechanisms that regulate the function of the selectins and their ligandsQ28295581
HCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cellsQ28303879
A perspective on cancer cell metastasisQ28307891
Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometryQ28360826
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cellsQ28578219
IL-1 is required for tumor invasiveness and angiogenesisQ28594748
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisitedQ29547915
The distribution of secondary growths in cancer of the breast. 1889Q29614314
Cancer metastasis: building a frameworkQ29616783
Breast cancer metastasis: markers and modelsQ29618061
Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivoQ30469729
Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivoQ30469918
Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.Q30478953
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftmentQ30484167
Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking.Q30491779
Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditionsQ30492454
Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodesQ30493442
A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophilsQ30504374
Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexityQ30937269
CD44v4 is a major E-selectin ligand that mediates breast cancer cell transendothelial migrationQ33324402
The therapeutic promise of the cancer stem cell conceptQ33559711
Differential effects of cream, glucose, and orange juice on inflammation, endotoxin, and the expression of Toll-like receptor-4 and suppressor of cytokine signaling-3Q33804798
Elevated endotoxin levels in non-alcoholic fatty liver diseaseQ33864406
Metastatic patterns of prostate cancer: an autopsy study of 1,589 patientsQ33904020
Identification and targeting of cancer stem cellsQ33921460
Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tailQ34092493
LPS-induced cytokine production in human dendritic cells is regulated by sialidase activityQ34378741
Divergent fates of P- and E-selectins after their expression on the plasma membraneQ34439087
Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesionQ34451438
Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cellsQ34573227
Involvement of CD44, a molecule with a thousand faces, in cancer dissemination.Q34777492
IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.Q34976406
Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cellsQ35172452
A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cellsQ35578307
Ligands for L-selectin: homing, inflammation, and beyondQ35698423
Expression of endothelial leukocyte adhesion molecule-1 in septic but not traumatic/hypovolemic shock in the baboonQ35830409
Chemokine receptors and melanoma metastasisQ35935290
Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvesselsQ36168394
Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic interventionQ36180251
Inhibition of tumor growth in vivo with a soluble CD44-immunoglobulin fusion proteinQ36231630
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.Q36235481
Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exonsQ36236359
Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronanQ36236582
Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronanQ36254851
P-selectin deficiency attenuates tumor growth and metastasisQ36257237
A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between themQ36322724
Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune responseQ36363335
Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.Q36363467
Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cellsQ36364000
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylationQ36365180
Glycosylation of CD44 negatively regulates its recognition of hyaluronanQ36365225
Redirection of tumor metastasis by expression of E-selectin in vivoQ36366262
Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 functionQ36380973
Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout miceQ36404584
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoidsQ36537945
Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genesQ36719253
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrowQ36735787
Hyaluronan in tissue injury and repairQ36824173
The metastatic niche: adapting the foreign soilQ36928869
Inflammation: a driving force speeds cancer metastasisQ36986448
Branched N-glycans regulate the biological functions of integrins and cadherins.Q37126755
Glycoforms of human endothelial CD34 that bind L-selectin carry sulfated sialyl Lewis x capped O- and N-glycansQ37268934
Relation between stage, grade, proliferation, and expression of p53 and CD44 in adenomas and carcinomas of the colorectumQ37270887
A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculatureQ37368363
Colon cancer metastasis: MACC1 and Met as metastatic pacemakersQ37576722
Glycome profiling using modern glycomics technology: technical aspects and applicationsQ37686527
The CXCR4/SDF-1 chemokine axis: a potential therapeutic target for bone metastases?Q37694721
Selectins promote tumor metastasis.Q37746080
Integrin activation in the immune systemQ37787936
Sialidases in vertebrates: a family of enzymes tailored for several cell functionsQ37788386
The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.Q37830915
Contribution of platelets to tumour metastasis.Q37831798
CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?Q37851351
CD44 expression on activated B cells. Differential capacity for CD44-dependent binding to hyaluronic acidQ38313485
Stimulation of hyaluronan synthesis by tumor necrosis factor-alpha is mediated by the p50/p65 NF-kappa B complex in MRC-5 myofibroblastsQ38328148
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.Q38341433
Benzyl-alpha-GalNAc inhibits sialylation of O-glycosidic sugar chains on CD44 and enhances experimental metastatic capacity in B16BL6 melanoma cells.Q38351597
Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x.Q38352062
In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expressionQ39172853
Differential use of chondroitin sulfate to regulate hyaluronan binding by receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages.Q39563161
Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasisQ40006251
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.Q40017311
Targeting of CD44 eradicates human acute myeloid leukemic stem cellsQ40228130
Monocyte differentiation up-regulates the expression of the lysosomal sialidase, Neu1, and triggers its targeting to the plasma membrane via major histocompatibility complex class II-positive compartmentsQ40256626
Chondroitin sulfate addition to CD44H negatively regulates hyaluronan binding.Q40400787
Physiologic migration of lymphocytes to lymph nodes following bone marrow transplantation: role in immune recoveryQ40491141
TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.Q40702477
Characterization of glycoprotein ligands for P-selectin on a human small cell lung cancer cell line NCI-H345.Q40772774
Role of sulfation in CD44-mediated hyaluronan binding induced by inflammatory mediators in human CD14(+) peripheral blood monocytesQ40773051
differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1.Q40776175
Human neutrophils facilitate tumor cell transendothelial migration.Q40821335
CD44 and its interaction with extracellular matrix.Q40850240
Cutting edge: an inducible sialidase regulates the hyaluronic acid binding ability of CD44-bearing human monocytesQ40956675
Expression of antisense CD44 variant 6 inhibits colorectal tumor metastasis and tumor growth in a wound environment.Q41012070
Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding.Q41012218
P-selectin mediates adhesion of the human melanoma cell line NKI-4: identification of glycoprotein ligandsQ41023766
A hematopoietic cell L-selectin ligand exhibits sulfate-independent binding activity.Q41115859
CD15 expression in human myeloid cell differentiation is regulated by sialidase activityQ41145573
CD44: structure, function, and association with the malignant process.Q41438683
L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectinQ41532547
Tumor necrosis factor stimulates epithelial tumor cell motilityQ41662781
CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell linesQ41663734
Hyaluronan binding by cell surface CD44.Q41743967
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascadeQ42178238
Chylomicrons induce E-selectin and VCAM-1 expression in endothelial cellsQ42443952
Effects in humans of intravenously administered endotoxin on soluble cell-adhesion molecule and inflammatory markers: a model of human diseasesQ42505042
Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues.Q42827719
Inhibition of colon carcinoma cell lung colony formation by a soluble form of E-selectin.Q42840045
Prevention of tumor metastasis formation by anti-variant CD44.Q42941570
A crucial role of sialidase Neu1 in hyaluronan receptor function of CD44 in T helper type 2-mediated airway inflammation of murine acute asthmatic modelQ43057294
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitisQ44049997
Tumor necrosis factor-alpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cellsQ44516197
Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour developmentQ44683813
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.Q44781757
Quantitation of cell shedding into efferent blood of mammary adenocarcinomaQ45073003
L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrestQ46923194
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrowQ47800956
Locomotion of monocytes on endothelium is a critical step during extravasationQ47949622
CD44 and variants in melanocytic skin neoplasmsQ48021465
Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alphaQ48165077
G-CSF induces E-selectin ligand expression on human myeloid cells.Q51803913
Expression of variant CD44-messenger RNA in colorectal adenocarcinomas and adenomatous polyps in humans.Q53457031
Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chainQ60043779
Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factorsQ60673557
Expression of CD44v6 is associated with cellular dysplasia in colorectal epithelial cellsQ70901545
O-linked glycosylation modifies CD44 adhesion to hyaluronate in colon carcinoma cellsQ71657359
Expression of CD44 splice variants in human cutaneous melanoma and melanoma cell lines is related to tumor progression and metastatic potentialQ71702894
CD44 isoforms correlate with cellular differentiation but not with prognosis in human breast cancerQ71805116
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progressionQ72097100
Exhausted platelets in patients with malignant solid tumors without evidence of active consumption coagulopathyQ72819866
Loss of standard type of CD44 expression in invaded area as a good indicator of lymph-node metastasis in colorectal carcinomaQ73003004
Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongueQ73088782
Immunohistochemical expression of the CD44 variant 6 in colorectal adenocarcinomaQ73386116
Expression of CD44, vascular endothelial growth factor, and proliferating cell nuclear antigen in severe venous invasional colorectal cancer and its relationship to liver metastasisQ73745243
Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvesselsQ73998199
Blockade of metastasis formation by CD44-receptor globulinQ74323898
CD44-dependent lymphoma cell dissemination: a cell surface CD44 variant, rather than standard CD44, supports in vitro lymphoma cell rolling on hyaluronic acid substrate and its in vivo accumulation in the peripheral lymph nodesQ77080656
Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasisQ78313520
Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicronsQ78826897
CD44-hyaluronic acid interactions mediate shear-resistant binding of lymphocytes to dermal endothelium in acute cutaneous GVHDQ79077287
Effects of continuous low-dose infusion of lipopolysaccharide on expression of E-selectin and intercellular adhesion molecule-1 messenger RNA and neutrophil accumulation in specific organs in dogsQ81087657
Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokinesQ81657102
The Relationships Between Loss of Standard CD44 Expression and Lymph Node, Liver Metastasis in T3 Colorectal CarcinomaQ84949674
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)3148-3158
P577publication date2011-08-05
P1433published inFEBS LettersQ1388051
P1476titleCD44 and HCELL: preventing hematogenous metastasis at step 1.
P478volume585

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