Endothelial protein C receptor gene variants not associated with severe malaria in ghanaian children

scientific article published on 26 December 2014

Endothelial protein C receptor gene variants not associated with severe malaria in ghanaian children is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k5770S
P356DOI10.1371/JOURNAL.PONE.0115770
P8608Fatcat IDrelease_pfncbgojpngzjm3rqap2hwk5bu
P932PMC publication ID4277309
P698PubMed publication ID25541704
P5875ResearchGate publication ID270001724

P50authorDaniel AnsongQ56552935
Tsiri AgbenyegaQ80353091
Rolf D HorstmannQ114072590
P2093author name stringKathrin Schuldt
Jennifer Evans
Christa Ehmen
Juergen Sievertsen
Birgit Muntau
Juergen May
Gerd Ruge
P2860cites workHow malaria has affected the human genome and what human genetics can teach us about malariaQ21032480
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Organization and chromosomal localization of the human endothelial protein C receptor geneQ28138390
Structural and functional implications of the intron/exon organization of the human endothelial cell protein C/activated protein C receptor (EPCR) gene: comparison with the structure of CD1/major histocompatibility complex alpha1 and alpha2 domainsQ28139081
The cytoprotective protein C pathwayQ28274500
Pooled association tests for rare variants in exon-resequencing studiesQ28743126
Genome-wide association study indicates two novel resistance loci for severe malariaQ28943391
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studiesQ29614926
Score tests for association between traits and haplotypes when linkage phase is ambiguousQ29616281
Methods for detecting associations with rare variants for common diseases: application to analysis of sequence dataQ33359015
A groupwise association test for rare mutations using a weighted sum statisticQ33408787
Visualizing SNP statistics in the context of linkage disequilibrium using LD-PlusQ33647964
Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk.Q50889046
High levels of protein C are determined byPROCRhaplotype 3Q63359093
A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosisQ79202743
Role of a 5'-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor geneQ83181552
PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study.Q33798215
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumQ33817075
Testing for an unusual distribution of rare variantsQ33847792
A -436C>A polymorphism in the human FAS gene promoter associated with severe childhood malariaQ33916803
Evidence of promiscuous endothelial binding by Plasmodium falciparum-infected erythrocytesQ33967171
Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populationsQ34163026
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in childrenQ34276755
Severe malaria is associated with parasite binding to endothelial protein C receptorQ34348881
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC studyQ34450740
Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: the Athero Gene studyQ34471057
Hemoglobin variants and disease manifestations in severe falciparum malariaQ34630890
Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant toolsQ35708502
The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies.Q35849271
Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African childrenQ37065724
Plasmodium falciparum picks (on) EPCR.Q37464100
Genetic and genomic analyses of host-pathogen interactions in malariaQ37589280
Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malariaQ37731569
The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.Q37942050
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
endotheliumQ111140
P304page(s)e115770
P577publication date2014-12-26
P1433published inPLOS OneQ564954
P1476titleEndothelial protein C receptor gene variants not associated with severe malaria in ghanaian children
P478volume9

Reverse relations

cites work (P2860)
Q90176965Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria
Q36354336Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
Q90341629Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Q36336828Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania
Q50095537Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a PfEMP1 subtype associated specifically with cerebral malaria
Q36965217The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria
Q38861442Triggering receptor expressed on myeloid cells 1 (TREM-1) and cytokine gene variants in complicated and uncomplicated malaria