Severe malaria is associated with parasite binding to endothelial protein C receptor

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Severe malaria is associated with parasite binding to endothelial protein C receptor is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1022255124
P356DOI10.1038/NATURE12216
P932PMC publication ID3870021
P698PubMed publication ID23739325
P5875ResearchGate publication ID237059246

P50authorLouise TurnerQ43240630
Matthew K. HigginsQ43240638
Morten Agertoug NielsenQ44227553
Thor G. TheanderQ54802168
Sanne S BergerQ55176215
Christian W. WangQ55182133
Jakob S JespersenQ56605506
Thomas LavstsenQ80377133
John LusinguQ90228924
Pamela MagistradoQ114320963
P2093author name stringJoseph D Smith
Marion Avril
Jim Freeth
Jens E V Petersen
Andrew J Brazier
P2860cites workGlobal malaria mortality between 1980 and 2010: a systematic analysisQ20905423
Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptorQ24323189
Structural and functional implications of the intron/exon organization of the human endothelial cell protein C/activated protein C receptor (EPCR) gene: comparison with the structure of CD1/major histocompatibility complex alpha1 and alpha2 domainsQ28139081
Metalloproteolytic release of endothelial cell protein C receptorQ28145146
The cytoprotective protein C pathwayQ28274500
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquerQ33700519
Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcomeQ33842019
Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications.Q33884983
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteersQ34103586
Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasitesQ34244920
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in childrenQ34276755
A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cellsQ34276761
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cellsQ34276770
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian childrenQ34290645
Evidence for the involvement of VAR2CSA in pregnancy-associated malariaQ34364093
A family affair: var genes, PfEMP1 binding, and malaria diseaseQ34543611
The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies.Q35849271
Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.Q36124623
The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.Q37331775
The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.Q37942050
The use of drotrecogin alfa in severe falciparum malaria.Q38871998
Expression and function of the endothelial protein C receptor in human neutrophilsQ44417143
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domainsQ44605152
The use of activated protein C in severe Plasmodium falciparum malariaQ47836632
Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genomeQ47923917
Drotrecogin alfa (activated) in severe falciparum malariaQ48034493
Selective expression of adhesion molecules on human brain microvascular endothelial cellsQ48697836
Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.Q51732026
High levels of protein C are determined byPROCRhaplotype 3Q63359093
The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptorQ71144272
P4510describes a project that usesImageQuantQ112270642
P433issue7455
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
endotheliumQ111140
P304page(s)502-505
P577publication date2013-06-05
P1433published inNatureQ180445
P1476titleSevere malaria is associated with parasite binding to endothelial protein C receptor
P478volume498

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